Conformational switch
Effects of an Early Conformational Switch Defect during ϕX174 Morphogenesis Are Belatedly Manifested Late in the Assembly Pathway
... In contrast, the su(B111)-F H203Y mutation, which is located in the large ␣-helix at the 3-fold axis of symmetry, exhibited some allele specificity. Substitutions in this helix have pleotropic effects. They suppress ...
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Evaluation of the Conformational Switch Model for Alfalfa Mosaic Virus RNA Replication
... the conformational switch model was the observation that replication activity was disrupted by mutating the pseudoknot pairing nucleotides but rescued when compensatory mutations that restore pseudoknot ...
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Conformational Switch-Defective ϕX174 Internal Scaffolding Proteins Kinetically Trap Assembly Intermediates before Procapsid Formation
... The other lethal substitutions appeared to kinetically trap B- protein-containing intermediates. The 9S* particle; which con- tains coat, internal scaffolding, and DNA pilot proteins in a 5:5:1 ratio, was the predominant ...
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A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies
... a conformational switch such that neutralization can occur by the recognition of the different conformations and faces of the largely amphipathic ...
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The Hedgehog induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
... and conformational state of the ...Smo conformational switch assembles active Smo-Cos2-Fu signaling complexes that promote Fu kinase domain dimerization and activation loop phosphorylation, leading ...
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Complete Virion Assembly with Scaffolding Proteins Altered in the Ability To Perform a Critical Conformational Switch
... the conformational switch mediated by glycine residue 61 of the X174 external scaffolding protein is critical for proper ...The switch allows ␣ -helix 3 to assume one of two conformations, straight ...
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In Vitro and In Vivo Studies of the RNA Conformational Switch in Alfalfa Mosaic Virus
... the switch between CPB and TL conformers was further ...this conformational switch in the yeast three-hybrid ...the conformational switch in the 3 ⴕ UTR of AMV ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... Understanding the real economic climate in the South provides us with the tools to challenge the one-dimensional representations of moonshiners in popular culture and also understand how[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... As discussed in Section 2 and Appendix A, the principal input parameters are the intrinsic pK’s of the two carboxylic acid groups of malonic acid, pK1 and pK2, the net number of charge s[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... Jyll Walsh- Preliminary Analysis of HAPI and BCAP Relationship Current Research Because, as noted earlier, childhood injuries can occur as a function of CM, especially child neglect, and[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... scholar Christopher Marsden’s 2010 Net Neutrality: Towards a Co-Regulatory Solution intervenes in the debate by offering an approach to neutrality that reconciles the industrial and poli[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... This means that over the past five years, a discipline that is focused on taking a “user-‐centered approach to providing the right information, in the righ[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... To estimate the occupancy under the assumption that massive number of occupants is involved, a reduced order model has been developed; instead of consider each agent’s position as the st[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... While in Surinam she explains that she relates to the people in Surinam through strange “lines of faith which tied together my own history and theirs, in the form of our mutual connectio[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... After we randomly split the original data into training and test sets, and build and evaluate both models for 200 times, Tables 10.6 and 10.7 show the statistics mean and variance of thr[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... 8 received additional attention, this time from Elizabeth Freudenthal in her work, “Anti-‐ Interiority: Compulsiveness, Objectification, and Identity in Infinite Jes[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... For example, the scarcity of stories in the Englishlanguage press about urban poverty provides a false impression about where the most impoverished are living; and, while the English-lan[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... Description “School discipline and self discipline: A Practical Guide to Promoting Student Prosocial Behavior” "Effective School Interventions; Strategies for Enhancing Social Competence[r] ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... subpopulations of the conformational space of the substrate in the active site of Pin1. The simulations show that the enzyme–substrate interactions are coupled to the state of the prolyl peptide bond during ...
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Molecular Dynamics Simulations Towards The Understanding of the Cis Trans Isomerization of Proline As A Conformational Switch For The Regulation of Biological Processes
... In order to understand this relationship, the evaluation needs to examine the impact of HS program activities on KPGA members’ with diabetes health and economic outcomes.. Since HS is in[r] ...
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