Conserved C-terminal motif
C-terminal domain of SMYD3 serves as a unique HSP90- regulated motif in oncogenesis
... and C-terminal portions of the “split-SET” domain (N-SET and C-SET) adopt a canonical SET domain fold and closely assemble with the MYND (Myeloid translocation protein 8, Nervy, and DEAF-1) zinc- ...
15
Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition
... a C-terminal restriction EN-like EN (Yang et ...the C-terminal EN function was ...and C-terminal) (Kojima and Fujiwara 2005). Further, the CCHC motif is common to both L1 ...
11
A dual-targeted purple acid phosphatase in Arabidopsis thaliana moderates carbon metabolism and its overexpression leads to faster plant growth and higher seed yield
... this C-terminal motif could only be found in plants, not in animals (Supporting Information ...a C-terminal hydrophobic region (AtPAP2 and AtPAP9), only a single PAP-like sequence from ...
15
Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study
... were conserved in all Plas- modium and mammalian sequences, blue colour for only motifs conserved in mammalian species and green col- our for motifs conserved only in Plasmodium sequences (Additional ...
27
The Hypervariable Domain of the Murine Leukemia Virus Surface Protein Tolerates Large Insertions and Deletions, Enabling Development of a Retroviral Particle Display System
... and C-terminal sequences of SU are independent glob- ular domains (20, 35), with receptor-binding activity residing in the N-terminal domain (2–4, 10, 25, ...a conserved core of b sheets in an ...
7
Evolutionary Conservation of Eukaryotic and Archaeal Box C/D Ribonucleoprotein Complex Structure
... on conserved sequence and structural elements ...The conserved features are bound by common core proteins for each snoRNA family to form a ribonucleoprotein particle ...box C/D snoRNAs possess ...
137
Conserved Gene Regulatory Function of the Carboxy-Terminal Domain of Dictyostelid C-Module-Binding Factor
... Preliminary data have suggested that the JmjC/ZF portion of CbfA is sufficient to rescue JH.D cell development in the absence of the CbfA CTD, which would imply that the two domains of the CbfA protein function ...
9
Bemeleit, Derk Julius (2008): Structural Characterization of the DNA Repair Protein Complex SbcC-SbcD of Thermotoga maritima. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... (orange) motif carrying the ATPase activity, two heptad repeats folding into an antiparallel coiled-coil domain and a central Cys-X-X-Cys (CXXC, purple) motif forming a zinc hook that facilitates a ...
138
The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites
... larger C-terminal lobe (C-lobe) with the active site sand- wiched between the N-lobe and C-lobe (Pearce et ...several conserved sites is necessary for their catalytic function. A ...
17
The Highly Conserved C-Terminal Dileucine Motif in the Cytosolic Domain of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Is Critical for Its Association with the AP-1 Clathrin Adapter
... the C-terminal dileucine in combination with a Y712A change leads to increased cell surface expression of ...the C-terminal dileucine in modulation of cell surface ex- pression was gained in ...
12
Autographa californica Multiple Nucleopolyhedrovirus DNA Polymerase C Terminus Is Required for Nuclear Localization and Viral DNA Replication
... highly conserved and are considered func- tional in DNA ...DNApol C terminus has not yet been ...DNApol C-terminal truncations were cloned into a dnapol-null AcMNPV bacmid with a green ...
16
Modeling the Structure of Yeast MATα1: An HMG Box Motif with a C Terminal Helical Extension
... remarkably conserved in α-domains and HMG-box ...the conserved HMG-box motif contains an extended heli- cal region for about 20 - 30 amino ...
12
Adhesins in Human Fungal Pathogens: Glue with Plenty of Stick
... and C) Sequence logos (created at ...purple, conserved tryptophan in the Iff group, cysteines, and prolines; green, amyloid forming (TLVIA); red, positively charged (KRH); blue, negatively charged (DE); ...
12
Regulation of Protein Kinase C function by phosphorylation on conserved and non conserved sites
... Kinase C (PKC) is a family of phospholipid-dependent serine/threonine kinases that play key roles in many of the signalling pathways that control cellular growth, proliferation, differentiation and cell death ...
52
Insights into Chibby's structural elements and their interplay in Wnt signaling protein-protein interactions
... the C-terminal half of Cby alone can bind to β- catenin ...Cby’s C-terminal half contains the coiled-coil region and a disordered C-terminal extension ranging from residues ...
172
Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar
... and C‑terminal non‑repeat regions of Myanmar PfCSP showed limited genetic ...the C‑terminal region of Myanmar and global PfCSP were found in the Th2R and Th3R regions, where natural selection ...
14
Synthesis, Assembly, and Processing of the Env ERVWE1/Syncytin Human Endogenous Retroviral Envelope
... Conclusion. The results presented here provide evidence that the syncytin/HERV-W envelope glycoprotein expressed in placental trophoblastic BeWo cells is synthesized as a gPr73 precursor which is specifically cleaved at ...
9
Page_unc_0153D_15827.pdf
... assessment of enrichment within non-conserved features. For future probing of receiver domains, there are two potentially informative avenues. First, the enrichment of D+2 and T+2 pairs in a subfamily accounted ...
127
Structural insights into the regulation of PLC-[beta]2
... Heterotrimeric G protein subunits of the Gαq family were initially shown to stimulate the phospholipase activity of PLC-β isozymes 26-28 . Further characterization of the interactions of these proteins with PLC-β ...
106
Novel Structure and Unexpected RNA-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21
... The three identical residues in UL21C are Q346, N395, and L521 (Fig. 3). The side chain of L521 is buried and is likely neces- sary for structural integrity. In contrast, the side chains of Q346 and N395 are mostly ...
13