Contact Inhibition
Michael Abercrombie: contact inhibition of locomotion and more
... of contact inhibition of locomotion in vivo Upon identifying CIL between chick heart embryonic fibro- blasts, Abercrombie, speculated on its importance within living ...cell-cell contact and creates ...
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PDGF A suppresses contact inhibition during directional collective cell migration
... The control of lamellipodial stability by PDGF-A is linked to the directionality of LEM migration (Nagel et al., 2004). Previously, a PDGF-A gradient in the BCR matrix had been proposed to orient LEM cells (Nagel et al., ...
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State Diagram for Contact Inhibition of Proliferation: A Quantitative Framework for Modulating Growth Patterns in Epithelial Cell Clusters
... between contact and GFs is that the underlying mechanisms are arranged into a complex physiochemical ...regulate contact-inhibition through mechanotransduction ...cell-cell contact and GFs to ...
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Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion
... that contact inhibition of locomotion (CIL) is essential for morphogenesis and its failure is thought to be responsible for cancer invasion; however, the molecular bases of this phenomenon are poorly ...
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Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
... The Hippo signaling pathway appears to be conserved in mammals. Mammals have multiple Hippo pathway-component counterparts, and some of them rescued fly mutants and/or showed similar activities in flies (Lai et al., ...
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Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial mesenchymal transition in human hepatocarcinoma
... ates contact inhibition ...by contact inhibition (Figure 7A, ...lost contact inhibition by virtue of inability to sense neighboring ...
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RhoE is required for contact inhibition and negatively regulates tumor initiation and progression
... of contact inhibition; b) cooperates with oncogenes in cellular transformation; c) increases susceptibility to chemical carcinogens in vivo; and d) increases the metastatic potential of cancer ...
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Emergence of embryonic pattern through contact inhibition of locomotion
... In order to quantify the spacing of the haemocyte domains, a contour plot was taken of the domain map and the distance between contour peaks measured. Interestingly, the domains showed an even spacing of ~34 m (Fig. ...
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Cellular Deoxyribonucleic Acid Synthesis and Loss of Contact Inhibition in Irradiated and Contact-Inhibited Cell Cultures Infected with Fibroma Virus
... Infection appears to initiate in tures of DRK cells undergo characteristic changes irradiated or contact-inhibited cultures the same in cell morphology and then multiply in an ab- sequen[r] ...
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Shape meets polarity in Japan
... ‘contact inhibition of locomotion’, a term coined many years ago to describe a behavior of fibroblast cells in culture: some cells stop crawling or change direction upon contact with other cells ...
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Integrin linked kinase regulates p38 MAPK dependent cell cycle arrest in ureteric bud development
... The integrin-linked kinase (ILK), pinch and parvin ternary complex connects the cytoplasmic tails of 1 integrins to the actin cytoskeleton. We recently showed that constitutive expression of ILK and alpha parvin in ...
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Locust Wind Receptors
... In summary, the results of this section suggest that in locusts, neither release from tarsal contact inhibition nor onset of the jump wind detected by the facial setae initiates reflexiv[r] ...
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In silico characterization of cell–cell interactions using a cellular automata model of cell culture
... times and initial cell numbers, with cell–cell interac- tion properties as variables. The proliferation could be simulated and we could determine their cell–cell inter- action properties. HOS and HeLa cancer cells ...
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A global sensitivity analysis approach for morphogenesis models.
... Morphogenesis is a complex biological process in which cells organize into shapes and patterns. Computational modeling is used to get insights in the mechanisms of morphogenesis. These models are often multi-scale, non- ...
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Respiratory Syncytial Virus Fusion Protein Mediates Inhibition of Mitogen-Induced T-Cell Proliferation by Contact
... after contact with RSV-infected and UV-inactivated cells or with cells expressing RSV envelope proteins on the cell ...direct contact with RSV F is necessary and sufficient to inhibit proliferation of ...
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Perault_unc_0153D_19293.pdf
... encode Contact-Dependent growth Inhibition (CDI) ...growth inhibition or death unless the target cells produce a cognate immunity ...but Contact-Dependent Signaling (CDS) phenotypes were not ...
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Use of HPHT Autoclave to Determine Corrosion Inhibition by Berberine extract on Carbon Steels in 3.5% NaCl Solution Saturated with CO2
... Thus, in aqueous solutions, berberine exists either as neutral molecules or in the form of cations (protonated berberine). The neutral berberine may be adsorbed on the metal surface involving the displacement of water ...
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Within a Day Detection and Rapid Characterization of Carbapenemase by Use of a New Carbapenem Inactivation Method Based Test, CIMplus
... At the same time, to characterize the type of carbapenemase, 2 other suspensions were prepared, using the same protocol as for carbapenemase detection, to which were added inhibitors, i.e., either 0.05 M EDTA ...
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PubMedCentral-PMC5063142.pdf
... We further characterized the binding of the compounds over the production runs, looking at the statistical distribution of the direct interactions (H-bonds and hydrophobic contacts) between each ligand (AA, FLP, and ...
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Osmotic stress in colony and planktonic cells of Pseudomonas putida mt-2 revealed significant differences in adaptive response mechanisms
... water contact angles lower 20° represent hydrophilic surfaces, values between 20° and 70° mean intermediate hydrophilic/hydrophobic, whereas hydrophobic surfaces show contact angles >70° (van Loosdrecht ...
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