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CULTURED MAMMALIAN CELLS

MUTATION SYSTEMS IN CULTURED MAMMALIAN CELLS *

MUTATION SYSTEMS IN CULTURED MAMMALIAN CELLS *

... Evidence has been presented that in certain mutator strains of Chinese hamster ovary CHO cells, the spontaneous mutation rates were 5- to 50-fold higher than those in parental cells for [r] ...

10

Persistent infection of cultured mammalian cells by Japanese encephalitis virus.

Persistent infection of cultured mammalian cells by Japanese encephalitis virus.

... We have shown that persistently infected MA111 cells cannot be superinfected with wt JEV and that virus released from persistent infections can interfere with wt infection of normal MATA[r] ...

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56. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (ex vivo) by medicinal plants from western ghats

56. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (ex vivo) by medicinal plants from western ghats

... In cultured mammalian cells such as human fibroblasts, the activity of HMG CoA reductase, and hence, the formation of mevalonate is controlled through a feedback mechanism mediated by cholesterol ...

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Viral Cre-LoxP tools aid genome engineering in mammalian cells

Viral Cre-LoxP tools aid genome engineering in mammalian cells

... core spacer sequence flanked on either side by a 13 bp palindromic sequence [25, 26]. When a DNA element is flanked by two LoxP sites, the Cre recombinase recognizes the lox P sites and cuts it. The DNA element that is ...

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Attenuation of Bunyavirus Replication by Rearrangement of Viral Coding and Noncoding Sequences

Attenuation of Bunyavirus Replication by Rearrangement of Viral Coding and Noncoding Sequences

... in cultured mammalian cells and a slower disease progression in mice, produces small plaques, expresses reduced levels of L mRNA and L (RNA polymerase) protein, synthesizes less L genomic and ...

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Regulation of epithelial morphogenesis by Drosophila Rho GTPase and Abl kinase

Regulation of epithelial morphogenesis by Drosophila Rho GTPase and Abl kinase

... actin. Mammalian Abl-related gene (Arg) can bundle actin filaments in vitro, and expression of Abl or Arg in cultured mammalian cells causes rearrangement of the actin cytoskeleton (reviewed ...

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Evolution of genotoxicity test methods in Japan

Evolution of genotoxicity test methods in Japan

... In 1982, the MHW organized a research group of ex- perts to establish the guidelines for toxicity tests of drugs and undertook a review of the guidelines in Japan, referring to those of other countries [8]. In 1983, ...

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Structural chromosome aberrations cause swelling of the nucleus

Structural chromosome aberrations cause swelling of the nucleus

... the mammalian cell nucleus, a phenomenon first reported by Page ...in cultured mammalian cells (e.g., HeLa S3 cells) by Agrelo ...

10

AP Bio Ch. 12

AP Bio Ch. 12

...  Some of the initial evidence for this hypothesis came from experiments in which cultured mammalian cells at different phases of the cell cycle were fused to form a single cell with tw[r] ...

8

Efficient Single Base Editing in Mouse Using Cytosine Base Editor 4

Efficient Single Base Editing in Mouse Using Cytosine Base Editor 4

... in cultured mammalian cells, but it is barely confirmed and the efficiency is still very ...in cultured mammalian cells but has not been proven in ...in cells to ...

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Hyaluronic acid affects the in vitro induction effects of Synthetic PAMPS and PDMAAm hydrogels on chondrogenic differentiation of ATDC5 cells, depending on the level of concentration

Hyaluronic acid affects the in vitro induction effects of Synthetic PAMPS and PDMAAm hydrogels on chondrogenic differentiation of ATDC5 cells, depending on the level of concentration

... the cells and reduce the sensitivity of these receptors, resulting in a reduction of transduction of important molecules re- lated to cell ...ATDC5 cells, because the mechanical properties of a material ...

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Silk fibroins modify the atmospheric low temperature plasma treated poly (3 hydroxybutyrate co 3 hydroxyhexanoate) film for the application of cardiovascular tissue engineering

Silk fibroins modify the atmospheric low temperature plasma treated poly (3 hydroxybutyrate co 3 hydroxyhexanoate) film for the application of cardiovascular tissue engineering

... Tissue engineered scaffold is one of the hopeful ther- apies for the patients with organ or tissue damages. The key element for a tissue engineered scaffold ma- terial is high biocompatibility. Herein the poly (3- ...

10

The pX region of the bovine leukemia virus is transcribed as a 2.1-kilobase mRNA.

The pX region of the bovine leukemia virus is transcribed as a 2.1-kilobase mRNA.

... The origins of the RNAs were as follows: cultured normal cells 3010c and 3894c, normal corneal cells from enzootic lymphosarcoma cells [3010 and 3894]; cultured normal cells in vitro inf[r] ...

5

A study of vertebrate corticotrophins and related peptides

A study of vertebrate corticotrophins and related peptides

... Sqnalus acanthias. (X-MSII has previously been isolated and characterised from nenrointermodiate lobe extracts of this species (Lowry & Chadwick, 1970a). More recently, (Bennett, Lowry, McMartin and Scott,unpublished ...

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Antimicrobial Peptides: Classification, action and therapeutic potential

Antimicrobial Peptides: Classification, action and therapeutic potential

... Antibiotic resistance has proved to be a global burden. Emergence of antibiotic resistant strains of different pathogens has lead to discovery of antimicrobial peptides.From the last few decades antimicrobial peptides ...

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Immunological properties of a type C retrovirus isolated from cultured human T-lymphoma cells and comparison to other mammalian retroviruses.

Immunological properties of a type C retrovirus isolated from cultured human T-lymphoma cells and comparison to other mammalian retroviruses.

... A rabbit antiserum raised against disrupted HTLVcR precipitated the labeled p24, and the precipitation was competed for by unlabeled HTLVcR and by cytoplasmic proteins from cells produci[r] ...

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Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells

Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells

... in mammalian cells while establishing noncytopathic, persistent infections in mosquito ...fected mammalian cells, the morphological and structural elements of alphavirus replication and ...

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The effect of pathological concentrations of phytanic acid on the fatty acid composition, vitamin E concentration and function of membranes of cultured mammalian retinal cells

The effect of pathological concentrations of phytanic acid on the fatty acid composition, vitamin E concentration and function of membranes of cultured mammalian retinal cells

... The cells were allowed to attach for approximately 1 hour before the addition o f a further 3 ml ...medium. Cells were incubated at 37°C in a 5 %/C 0 2 humidified atmosphere ...

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Ricin trafficking in plant and mammalian cells

Ricin trafficking in plant and mammalian cells

... dendritic cells are thought to traffic in vesicular structures to reach the ER where they unfold to subvert ERAD and subsequently refold after reaching the cytosol ...the mammalian cell ...

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The growth cycle of poliovirus in cultured cells

The growth cycle of poliovirus in cultured cells

... infected cells present. This portion of the curve is determined by the first cells to release virus, and characterizes the extreme and not the most frequent cell ...

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