cytotoxic agent
One pot Multicomponent Synthesis of Some Pyridine 3 carbonitrile Derivatives and Their Biological Evaluation as Cytotoxic Agent
... their cytotoxic activity. Ten compounds exhibited cytotoxic potential against a panel of three human tumor cell ...of cytotoxic activity. Analog 35 was considered as the most active cytotoxic ...
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Pharmacological evaluation of ethnomedicinal Glycosmis pentaphylla Lour. as antidiabetic, antioxidant and cytotoxic agent
... In this study, we have investigated the methanol extract of a widely used ethnomedicinal plant G. pentaphylla to determine its usefulness as antidiabetic, antioxidant, and cytotoxic agent. The methanol ...
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TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A
... potent cytotoxic agent against some cancer cell lines developed from patients with these cancers ...of agent which are effective against certain types of cancer for which innovative treatment ...
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SYNTHESIS OF MANNICH BASES OF DESLORATADINE USING DIFFERENT TYPES OF ACTIVATED METHYLENE AROMATIC COMPOUNDS AS CYTOTOXIC AGENT
... toxic agent and against human cancer cell ...as cytotoxic agent, we planned to convert Desloratadine (1) into Mannich bases 2a, 2b, 2c & 3 [ Scheme 2] with activated methylene aromatic compounds ...
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A recombinant scFv-FasLext as a targeting cytotoxic agent against human Jurkat-Ras cancer
... Targeted therapy of human cancers has been considered by many investigators and remains an attractive ap- proach to avoid side effects of cancer treatment. Anti- CD95 (Fas) Ab that induces Fas + tumor apoptosis in vitro ...
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PHARMACOLOGICAL OVERVIEW OF PROANTHOCYANIDINS FROM THE BARK OF THESPESIA POPULNEA (L ) AS AN ANTIOXIDANT AND CYTOTOXIC AGENT
... In the present study, ethyl acetate and aqueous soluble proanthocyanidin fractions EASPA and AQSPA respectively were extracted and purified by chromatography on Sephadex LH-20.. Prussian[r] ...
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Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines
... Extraction, isolation and preparation of juglone analogs In this study, the different extracts of Juglans regia bark were prepared using hexane, chloroform, ethyl acetate and methanol separately and subjected to ...
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Synthesis and Preclinical Evaluation of a Highly Improved Anticancer Prodrug Activated by Histone Deacetylases and Cathepsin L
... masked cytotoxic agent puromycin [Boc-Lys(Ac)-Puromycin], which can be sequentially activated by histone deacetylases (HDACs) and cathepsin L (CTSL) to kill cancer cells expressing high levels of both ...
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Therapeutic treatment of New Zealand mouse disease by a limited number of anti idiotypic antibodies conjugated with neocarzinostatin
... conjugated with a cytotoxic agent, neocarzinostatin (NCS). In vivo administration of anti-Id antibodies conjugated with NCS brought about an improvement in the survival rate of female NZB/W F1 mice. It also ...
9
SCREENING OF ANTIDIABETIC (HYPOGLYCEMIC/ANTIHYPERGLYCEMIC) ACTIVITY OF EXTRACTS OF SPIRULINA AGAINST ALLOXAN INDUCED DIABETES IN RATS
... a cytotoxic agent induces chemical diabetes (alloxan diabetes) in various animal species through destruction of islets of langerhans of the pancreas, following which there is a formation of redox cycle for ...
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EBAG9 tempers lymphocyte killing activity
... Rüder and colleagues used various approaches to determine which step of cytotoxic granule biogenesis is regulated by EBAG9 expression (11). Their findings provide compelling evidence that EBAG9 does not directly ...
6
The phytochemical investigation and biological activity of Nepeta clarkei
... On basis of the results obtained in the present study, it is concluded that chloroform and n-hexane fractions of N. clarkei have shown potent antiglycation, anticancer, antiplatelet, phytotoxic, and cytotoxic ...
6
Game Based Multi Agent Equilibrium in Intelligent City Transportation System Design
... The new ways to solve the problem of the intelligent urban traffic using system theory and method are explored in the paper. Combining with multi-agent and game theory technology advantages, new thought and method ...
5
Synthesis, Characterization and in vitro Cytotoxic Evaluation of Some Novel Heterocyclic Compounds Bearing the Indole Ring
... Thiosemicarbazones has been used as intermediates for the preparation of many heterocyclic compounds. In the literature, manyresearchers have reported the S/N regioselective nucleophilic completion in the synthesis of ...
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Multiagent systems a modern approach to distributed artificial intelligence Gerhard Weiss pdf
... second agent, where each of the two agents now represents the goal it is to achieve as well as a parallel node in the network that represents a model of the other agent's ...an agent does so, it can ...
585
Formulation and Evaluation of Montelukast Sodium Chewabletablets by Direct Compression Method
... Dept. of Pharmaceutics 19 J.K.K.Nattraja college of pharmacy dissolution may become slower. In this case we can use soluble filler (Lactose) with a superdisintegrant.) When we use more than one compactable agent ...
80
Path Finding and Collision Avoidance in Crowd Simulation
... In each frame of the simulation, every agent needs to check for future collisions with all other agents in the scene. If a collision has been pre- dicted, the type of collision must be determined. Every pedestrian ...
12
Cytotoxic activity screening of ethyl acetate fungal extracts derived from the marine sponge Neopetrosia chaliniformis AR-01
... This research explored the potential of fungi derived from the marine sponge Neopetrosia chaliniformis as producers of cytotoxic compounds. Fungi derived from N. chaliniformis were isolated by cultivating on ...
5
Towards an Intelligent and Deeply Automated Shopping Bot
... In this paper we present a new intelligent shopping bot (iShopBot), based on multi-agent system, that address most important issues that hinder widespread shopping bots efficiency namely, accuracy, availability ...
7
A Trustable Software Agent Framework for the Examination Paper Preparation and Moderation Process (EPMP)
... In order to sustain the interactions between software agents, trust and trustworthiness is a crucial requirement. Several research in psychology, sociology, economics and computer science viewed it as relevance. This ...
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