dentate gyrus
Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus
... The intersections of Type III astrocytes were signifi- cantly increased at 10 μm from the cell body at 1 h but not at 24 h (control; 13.036 ± 0.669, 1 h; 15.618 ± 0.473, p < 0.01). At 15 μm, the number of intersec- ...
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Thioperamide-induced Antinociception is Mediated through Endogenous Opioid System in the Dentate Gyrus of Adult Rats
... the dentate gyrus may involve in modulation of ...the dentate gyrus have decreased the discharge frequency of pain- excited neurons, and increased the discharge frequency of pain-inhibited ...
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Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus
... This is the first study to demonstrate a role for CXCR5 in mammalian hippocampal neurobiology. CXCR5 reduces maintenance of immature neural cell populations and enhances proliferation of subgranular zone cells in the ...
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Smad3 is required for the survival of proliferative intermediate progenitor cells in the dentate gyrus of adult mice
... Results: We show that Smad3, an intracellular molecule involved in the transforming growth factor (TGF)- β signaling cascade, is strongly expressed by granule cells in the dentate gyrus (DG) of adult mice, ...
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The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats
... Increasing evidence has shown that diabetes may be associated with learning and memory deficits in humans [4, 5, 14]. Studies examining the effects of streptozotocin-induced diabetes on memory func- tion in mice and rat ...
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The effects of group II mGluR agonists on short term depression and neutral coding in the rat dentate gyrus in vitro
... The findings of this study into activity-dependent synaptic transmission in the medial perforant path of the dentate gyrus are in broad agreement with similar studies in the cortex. (Markram and Tsodyks, ...
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FGF 2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice
... We studied the role of FGF-2 on regulation of neurogenesis and cell loss in the granule cell layer (GCL) of the hippocampal dentate gyrus after experimental traumatic brain injury (TBI). In both FGF-2 –/– ...
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A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation
... Heterogeneity of quiescent RGL activation along the septo-temporal axis of adult mouse dentate gyrus Due to the curvature and orientation of the hippocampus (Fig. 1a), sectioning the brain in one of the ...
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Santoso, Ariane (2009): Cell proliferation and cell survival in the dentate gyrus of adult mice under naturalistic conditions. Dissertation, LMU München: Fakultät für Biologie
... the dentate gyrus (DG) in the hippocampal formation, where new cells are produced that partly become functional neurons in the granule cell layer (GCL) of the DG (van Praag et ...
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Morphological features of microglial cells in the hippocampal dentate gyrus of Gunn rat: a possible schizophrenia animal model
... cells with the processes and phagocytic pouches formed at the ends of the processes (Figure 6). This kind of phagocytic pouch is known as a modification of the pha- gocytosis function of microglial processes [31]. These ...
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Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
... the dentate gyrus of the adult ...which dentate gyrus granule cells fail to mature normally, TDO immunoreactivity was substantially downregulated in the dentate gyrus granule ...
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Functional alpha7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus.
... Using immunohistochemistry we have shown, in both rats and mice, the presence of α 7 nAChR subunits around granule cells close to the germinal layer in the subgranular zone. These fi ndings were con fi rmed with α ...
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The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus
... Measurement of evoked potentials. Signals were filtered between 0.1 Hz and 1 kHz, and then amplified (DAM-50 differential amplifier; World Precision Instruments, Hertfordshire, UK). Recordings were digitized online using ...
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Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus
... hippocampal dentate gyrus by using Tmem108 mutant ...the dentate gyrus and CA3 of the hippocampus. Dentate gyrus is a brain region where adult neurogenesis occurs, and aberrant ...
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Adult neurogenesis modifies excitability of the dentate gyrus
... Adult-born dentate granule neurons contribute to memory encoding functions of the dentate gyrus (DG) such as pattern ...mature dentate granule neurons in the DG of mice with more adult-born ...
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Functional synaptic plasticity in the dentate gyrus of the rat hippocampus
... embedded in gelatine, were frozen and sectioned coron- ally at 40 um intervals. The animals were previously involved in electrophysiological experiments, in which stimulation of both the dorsal and the ventral regions of ...
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Normal And Epilepsy-Associated Pathologic Function Of The Dentate Gyrus
... of dentate granule cells combine to make these neurons fundamentally reluctant to activate, one of their hallmark ...the dentate gyrus is one of the more heavily inhibited regions of the brain, with ...
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How to make a hippocampal dentate gyrus granule neuron
... immature dentate gyrus ’ (iDG) as a conserved pathophysiological alteration that is found in neuropsychiatric disorders, including schizophrenia and bipolar disorder (Reif et ...
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A STEREOLOGICAL ANALYSIS OF THE EFFECT OF EARLY POSTNATAL ETHANOL EXPOSURE ON NEURONAL NUMBERS IN RAT DENTATE GYRUS
... the dentate gyrus ...the dentate gyrus, and the physical disector method was used to estimate the numerical densities of neurons within each ...the dentate gyrus may be ...
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ApoE is required for maintenance of the dentate gyrus neural progenitor pool
... the dentate gyrus were counted (Lagace et al., 2007). For dentate gyrus volume quantification, the sections were stained with Nissl solution and estimated by Cavalieri ...
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