Desorption ionization
Fatal Nocardia farcinica Bacteremia Diagnosed by Matrix-Assisted Laser Desorption-Ionization Time of Flight Mass Spectrometry in a Patient with Myelodysplastic Syndrome Treated with Corticosteroids
... Laser Desorption-Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) has been developed for rapid identification of the majority of human pathogens, but hitherto it has been rarely used for Nocardia ...
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Evaluation of Two Protein Extraction Protocols Based on Freezing and Mechanical Disruption for Identifying Nontuberculous Mycobacteria by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry from Liquid and Solid Cultures
... laser desorption ionization–time of flight mass spectrometry (MALDI- TOF MS) has proven to be a rapid, cost-effective, and accurate technique for conven- tional bacterium and yeast identification (12, ...
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Utility of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry following Introduction for Routine Laboratory Bacterial Identification
... Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) was evaluated prospectively in a diagnostic laboratory. Nine hundred twenty-seven organisms were tested in ...
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Prospective Evaluation of a Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry System in a Hospital Clinical Microbiology Laboratory for Identification of Bacteria and Yeasts: a Bench by Bench Study for Assessing the Impact on Time to Identification and Cost Effectiveness
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has been found to be an accu- rate, rapid, and inexpensive method for the identification of bacteria and ...
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Differentiation of Streptococcus pneumoniae from Nonpneumococcal Streptococci of the Streptococcus mitis Group by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) fingerprinting has been introduced as a routine microbial identification tool and found widespread acceptance thanks to its broad ...
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Identification of Rare Pathogenic Bacteria in a Clinical Microbiology Laboratory: Impact of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry (MS) has become a powerful tool for routine identification in many clinical ...
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Advances in Identification of Clinical Yeast Isolates by Use of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) is a soft ionization technique that generates a protein-based spectral profile or “fingerprint” that is unique to a given ...
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Rapid metabolic profiling of Nicotiana tabacum defence responses against Phytophthora nicotianae using direct infrared laser desorption ionization mass spectrometry and principal component analysis
... (Laser desorption/ionization); LOX: (Lipoxygenase); MALDI: (Matrix assisted laser desorption/ionization); MRM: (Multiple reaction monitoring); MS: (Mass spec- trometry); MS/MS: (Tandem mass ...
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Implementation of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry in Routine Clinical Laboratories Improves Identification of Coagulase Negative Staphylococci and Reveals the Pathogenic Role of Staphylococcus lugdunensis
... laser desorption ionization–time of flight mass spec- trometry (MALDI-TOF MS) has emerged as a reliable, fast, and cost-effective alternative for bacterial species identification and is now widely used in ...
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Identification of clinical dermatophyte isolates obtained from Iran by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
... laser desorption/ionization-time-of-flight (MALDI-TOF) mass spectrometry (MS)-based strategy has facilitated the effective identification of clinical dermatophyte ...
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Comparison of Two Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry Methods with Conventional Phenotypic Identification for Routine Identification of Bacteria to the Species Level
... Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) is another molecular analytic tool which may prove helpful diagnostically. MALDI- TOF MS has been used extensively ...
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Dermatophyte Identification Using Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... laser desorption ionization–time of flight (MALDI- TOF) mass spectrometer (MS) for the identification of dermatophytes from clinical cultures was compared to that of dermatophyte identification using 28S ...
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Improved Identification of Yeast Species Directly from Positive Blood Culture Media by Combining Sepsityper Specimen Processing and Microflex Analysis with the Matrix Assisted Laser Desorption Ionization Biotyper System
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and powerful tool for microbial species identification (1, 3, 6, 12, ...
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Evaluation of a Simple Protein Extraction Method for Species Identification of Clinically Relevant Staphylococci by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has been used to identify various microorganisms in clinical laboratories, includ- ing Gram-positive bacteria, Gram-negative ...
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Evaluation of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Identification of Nontuberculous Mycobacteria from Clinical Isolates
... laser desorption ionization– time of flight (MALDI-TOF) has been recently applied to the identification of a wide range of microorganisms (2), mainly clin- ically significant bacteria and ...
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Antifungal Susceptibility Testing of Aspergillus spp by Using a Composite Correlation Index (CCI) Based Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Method Appears To Not Offer Benefit over Traditional Broth Microdilution Testing
... laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS)-based method for the differentiation between wild-type and non-wild-type isolates of 20 Aspergillus ...
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Evaluation of blood culture broths with lysis buffer to directly identify specific pathogens by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry methods
... Usefulness of matrix-assisted laser desorption ionization time-of-flight mass spectrometry to identify pathogens, including polymicrobial samples, directly from blood culture broths. [r] ...
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Identification of Highly Pathogenic Microorganisms by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: Results of an Interlaboratory Ring Trial
... Identification of Highly Pathogenic Microorganisms by MatrixAssisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: Results of an Interlaboratory Ring Trial Peter Lasch,a [r] ...
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Mass determination of major plasma proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
... any detectable spectra. The high protein con- tent of serum probably did not allow a high enough ratio of matrix to protein to provide for efficient ionization of undiluted specimens. Matrix usually needs to be in ...
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Impact of matrix assisted laser desorption/ionization time of flight mass spectrometric evaluation on the clinical outcomes of patients with bacteremia and fungemia in clinical settings lacking an antimicrobial stewardship program: a pre post quasi experimental study
... laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) combined with antimicrobial stewardship in patients with positive blood cultures; clinical outcomes ...
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