DNA BINDING AND IN VITRO CYTOTOXICITY STUDIES
DNA Binding, DNA Cleavage, BSA Binding, Antioxidant, Antibacterial Activity and Cytotoxicity Studies of Cu(II), Co(II) Complexes
... geometry. DNA binding ability was explored by different techniques which suggest that the complex bind to CT-DNA through intercalative mode and also studied the BSA binding ...The DNA ...
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Multifaceted studies of the DNA interactions and in vitro cytotoxicity of anticancer polyaromatic platinum(II) complexes
... higher cytotoxicity of all PCs in the “normal” MCF10A breast cell line relative to the MCF-7 breast cancer ...previous studies: for P L s, 56Me 2 phen > phen ≥ 44Me 2 bpy > dpq > bpy ≅ 23Me 2 dpq, and for A ...
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DNA BINDING AND CYTOTOXICITY STUDIES OF TERNARY COPPER(II) COMPLEXES CONTAINING HETEROCYCLIC BASES AND THIOUREA
... The binding behaviors of these complexes to cal thymus DNA (CT-DNA) were explored by spectroscopic titrations, emissions, viscosity measurements, and cyclic ...The binding constant value of ...
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In vitro cytotoxicity and molecular docking studies on Acanthophora spicifera
... _____________________________________________________________________________________________ ABSTRACT Acanthophora spicifera, the red algae which is used as fresh vegetables in some parts of Vietnam and the Philippines ...
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In Vitro Cytotoxicity Studies and Antioxidant activities of two wild yams
... the cytotoxicity and antioxidant properties of tuber ...expressed cytotoxicity against human lung carcinoma cell line (A-549) which was ascertained by MTT ...
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Studies of the Silencing of Baculovirus DNA Binding Protein
... Baculovirus DNA binding protein (DBP) binds preferentially single-stranded DNA in vitro and colocalizes with viral DNA replication ...viral DNA replication sites were formed, ...
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In vitro antioxidant and cytotoxicity studies of Curcuma amada Roxb. (Mango ginger)
... In fact, there are many medicinal plants, which are being consumed traditionally for the prevention of cancer because of their antioxidant property. Recently spices have been very much attracted by the scientists to ...
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SOAR Research Proposal Summer 2018 DNA Binding Rates and Cytotoxicity of Rhodium Compounds
... the DNA-binding rates of a series of these new rhodium compounds has begun in the Dunham laboratories with a SOAR summer ’17 project by Lauren Caronia, independent studies in Spring ’17 and Fall ‘17 ...
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Effect of Phyllanthus polyphyllus extract on DNA binding studies
... CT DNA within 0-400 M and the voltammetric responses were ...of DNA and absence of CT DNA are shown in Fig 3 and the electrochemical data are summarised in the Table ...CT DNA, the methanolic ...
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Role of the Adenovirus DNA-Binding Protein in In Vitro Adeno-Associated Virus DNA Replication
... single-stranded binding activity which promotes more efficient replication was already present in the extract from Ad-infected cells, we added RPA to this extract and saw no ...Ad DNA replica- tion takes ...
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Metal-free Synthesis of Mesoionic Imidazo[1,5-a]pyridines under μ-Wave Irradiation: Antibacterial Potentiality, Cytotoxicity and DNA Binding Studies
... uptake studies were also performed to ensure whether the cytotoxicity results correlated with the cellular ...their DNA binding studies have been ...future studies on these ...
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Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity
... Previous studies on neuronal cells with commercially avail- able cationic lipid formulations have shown low transfec- tion efficiency. 5 Herein, we have reported the preparation of cationic liposomes from the ...
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Synthesis, Characterization and Antimicrobial Activity of some Metal Complexes Derived from Thiazole Schiff Bases with In-vitro Cytotoxicity and DNA Cleavage Studies
... circular DNA into linear form and this shows that the control DNA alone does not show any apparent cleavage, whereas the ligand and its metal complexes do ...pBR322 DNA were tested with newly ...
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Phytochemical Studies And In Vitro Cytotoxicity Screening Of Piper Betle Leaf (Pbl) Extract
... to cytotoxicity studies on Hep-2 cell line using MTT and SRB ...potent cytotoxicity and hence, the probable anticancer property of the selected ...
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Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA
... previous studies using retro-indolicidin (43) and our structural approach indicate that plasticity in structure and interactions is critical for the action of ...to DNA, gel retardation and fluorescence ...
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STUDIES ON THE DNA BINDING ACTIVITY OF SCHIFF BASE DERIVED COMPOUNDS
... of DNA and RNA has received considerable attention in the field of recombinant DNA technology and medicinal ...in DNA) play an important role in gene regulation and disease/pathogen ...acid ...
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Spectroscopic and Molecular Docking Studies on DNA Binding Interaction of Podophyllotoxin
... The binding interaction of novel podophyllotoxin derivative, (3R,4R)-4- ((benzo[d][1,3]dioxol-5-yl)methyl)-dihydro-3-(hydroxy(3,4-dimethoxyphenyl) methyl) furan-2(3H)-one (PPT), with calf thymus DNA (ctDNA) ...
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Effect of Silk Strength by Dietary Supplementation of Silk Worm with 1,3,4 Thiadiazoles, In Silico and In Vitro Bombyx mori DNA Binding Studies
... mori, DNA binding assay, Tensile strength INTRODUCTION Silk biopolymer is a strongest natural fibre with low density, high resistance, good insulator, shimmers, shines and good affinity to ...
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In vitro anti microbial and DNA cleavage studies of benzimidazole derivatives
... The increase in bacterial resistance has attracted considerable interest in the discovery and development of new classes of antibacterial agents [1]. The new agents should preferably consist of chemical characteristics ...
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DNA fragments binding CTCF in vitro and in vivo are capable of blocking enhancer activity
... CTCF binding sequences selection, we pooled together three constructs, namely pPNT/EmP with the CTCF7 frag- ment inserted between the promoter and enhancer, and two controls-pPNT/EmPS with the CTCF7 fragment ...
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