EBNA, Epstein–Barr nuclear antigen
Girls homozygous for an IL 2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV associated lymphoproliferation
... Nonstandard abbreviations used: BTK, Bruton’s tyrosine kinase; CRP, C-reactive protein; EBNA, Epstein-Barr nuclear antigen; Eomes, eomesodermin; FACS, fluorescence-activated cell sorting[r] ...
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Human regulatory proteins associate with non coding RNAs from the EBV IR1 region
... the Epstein–Barr nuclear antigen leader protein (EBNA-LP), and occurs during cancer- associated latency III infection as well as in a rare latency program found in Burkitts lymphomas: ...
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Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.
... In contrast, the cells infected with the P3HR1 Epstein-Barr virus strain, a deletion mutant that cannot encode Epstein-Barr nuclear antigen 2 EBNA2 or a full-length EBNA-LP, expressed EB[r] ...
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Salivary and serum IL-10, TNF-α, TGF-β, VEGF levels in oropharyngeal squamous cell carcinoma and correlation with HPV and EBV infections
... Amplification of EBNA-2 gene: The nested PCR was carried out for amplification of Epstein-Barr nuclear antigen 2 (EBNA-2). The sequence of primers used for PCR was as follows: ...
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Characteristics of viral protein expression by Epstein-Barr virus-infected B cells in peripheral blood of patients with infectious mononucleosis.
... of Epstein-Barr virus (EBV) antigen-positive B cells in the peripheral blood of patients with infectious mononucleosis compared with that for latently EBV-infected individuals was examined by immu- ...
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Maintenance of Serum Immunoglobulin G Antibodies to Epstein-Barr Virus (EBV) Nuclear Antigen 2 in Healthy Individuals from Different Age Groups in a Japanese Population with a High Childhood Incidence of Asymptomatic Primary EBV Infection
... The EBNA-2-expressing vector pKCRE2 was made by subcloning the AccII-DraI fragment from the DNA clone P5 under the control of the SV40 early promoter in ...The EBNA-1-expressing vector pSVEBK was ...
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Identification of multiple Epstein-Barr virus-induced nuclear antigens with sera from patients with rheumatoid arthritis.
... * 88 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest By means of the protein immunoblot technique, the Epstein-Barr virus EBV nuclear antigen EBNA could be identified i[r] ...
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Identification of candidate genes with pro-apoptotic properties by functional screening of randomly fragmented C DNA libraries
... cdna libraries and then treated simultaneously with both the agonistic anti-cd95 antibody cH11 and hy- gromycin. after four weeks, surviving clones stably expressing antisense cdnas were picked manually to purify the ...
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Epstein-Barr virus nuclear antigen forms a complex that binds with high concentration dependence to a single DNA-binding site.
... 465 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A bacterially synthesized 28-kilodalton carboxyl-terminal fragment 28K-EBNA of Epstein-Barr virus nuclear antigen sh[r] ...
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The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies.
... PML-containing nuclear bodies and eventually induces redistribution of the PML pro- tein ...latency-associated nuclear protein of EBV, EBNA-5, also accumulates in the PML bodies at the early phase of ...
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Influence of the Epstein-Barr virus nuclear antigen EBNA 2 on the growth phenotype of virus-transformed B cells.
... Finally, it is interesting to note that the growth rate and saturation densities of the BL cell lines listed in Table 1, and serving as a source of transforming virus for the present exp[r] ...
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Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines.
... 3870-3878 0022-538X/87/123870-09$02.00/0 Copyright C 1987, American Society for Microbiology Monoclonal and Polyclonal Antibodies against Epstein-Barr Virus Nuclear Antigen 5 EBNA-5 Dete[r] ...
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Oncogenic Activity of Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) Is Down-Regulated by Lytic LMP-1
... the Epstein-Barr virus nuclear antigen-2 gene (pSG5-EBNA-2) with clone K at a 10:1 plasmid quantity ratio did not have a significant effect on LMP-1 quantity (lane 6 LMP-1 ⫽ ...
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The signaling pathways of Epstein-Barr virus-encoded latent membrane protein 2A (LMP2A) in latency and cancer
... Abbreviations used: BCR – B-cell receptor; BL – Burkitt’s lymphoma; EBER – EBV- encoded small non-polyadenylated RNA; EBNA – EBV nuclear antigen; EBV – Epstein- Barr virus; ERK – extrace[r] ...
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Interaction of the lymphocyte-derived Epstein-Barr virus nuclear antigen EBNA-1 with its DNA-binding sites.
... DNA filter binding assays and DNase I footprinting experiments showed that the intact Raji EBNA-1 protein recognized the two binding site loci in oriP and the BamHI-Q locus and no other [r] ...
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Conserved Region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain That Mediates Self-Association as well as Nuclear Localization and Nuclear Matrix Association
... activities. Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) contains various numbers of W1W2 repeats and a unique carboxyl-terminal Y1Y2 ...that EBNA-LP ...
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Epstein-Barr virus-specific intrathecal oligoclonal IgG production in relapsing-remitting multiple sclerosis is limited to a subset of patients and is composed of low-affinity antibodies
... for nuclear viral proteins released from dying cells ...continual antigen stimulation without a significant production of specific CSF and serum anti- bodies ...
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Functional domains of Epstein-Barr virus nuclear antigen EBNA-1.
... To identify the EBNA-1 nuclear localization signal, small oligonucleotides representing EBNA-1 sequences that encode clusters of basic peptides were transferred into two different vector[r] ...
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Up regulation of the Epstein-Barr virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection.
... 5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 EBNA-2 through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line Rael.. Activation of B-[r] ...
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5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael.
... American Society for Microbiology 5-Azacytidine Up Regulates the Expression of Epstein-Barr Virus Nuclear Antigen 2 EBNA-2 through EBNA-6 and Latent Membrane Protein in the Burkitt's Lym[r] ...
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