Ehrlichia chaffeensis
Isolation and characterization of Ehrlichia chaffeensis strains from patients with fatal ehrlichiosis
... Two new isolates of Ehrlichia chaffeensis (designated Jax and St. Vincent) were obtained from patients with fatal ehrlichial infections. Patients developed characteristic manifestations of severe disease ...
7
Genetic Diversity of the 28 Kilodalton Outer Membrane Protein Gene in Human Isolates of Ehrlichia chaffeensis
... The Ehrlichia chaffeensis 28-kDa outer membrane protein (p28) gene was sequenced completely by genomic walking with adapter ...E. chaffeensis (Arkansas strain) including the 25-, 26-, 27-, and 29-kDa ...
7
Detection of Antibodies to Anaplasma phagocytophilum and Ehrlichia chaffeensis Antigens in Sera of Korean Patients by Western Immunoblotting and Indirect Immunofluorescence Assays
... Because of South Korean agricultural practices and Korean geography, various types of ticks and arthropod vectors are commonly present and every year transmit the agents of sev- eral vector-borne diseases, such as scrub ...
6
Molecular Cloning and Characterization of the Ehrlichia chaffeensis Variable Length PCR Target: an Antigen Expressing Gene That Exhibits Interstrain Variation
... an Ehrlichia chaffeensis Arkansas genomic library by probing with ...anti-E. chaffeensis hyperimmune mouse ascitic ...E. chaffeensis, blood samples from seven patients with monocytic ...
7
Western and Dot Blotting Analyses of Ehrlichia chaffeensis Indirect Fluorescent Antibody Assay Positive and Negative Human Sera by Using Native and Recombinant E chaffeensis and E canis Antigens
... Ehrlichia chaffeensis, a gram-negative obligatory intracellular bacterium of monocytes and macrophages, is the causative agent of human monocytic ehrlichiosis (HME), a tick-borne zoonosis ...E. ...
8
Expression of a Gene Encoding the Major Antigenic Protein 2 Homolog of Ehrlichia chaffeensis and Potential Application for Serodiagnosis
... with Ehrlichia chaffeensis infec- tion (human monocytic ehrlichiosis [HME]) and infection with the human granulocytic ehrlichiosis agent are similar, consist- ing of fever, headache, and ...whole ...
5
Western immunoblotting analysis of the antibody responses of patients with human monocytotropic ehrlichiosis to different strains of Ehrlichia chaffeensis and Ehrlichia canis.
... Ehrlichia chaffeensis has been isolated from the blood of three patients with human monocytotropic ehrlichiosis (HME) (6, 7, ...1991, Ehrlichia canis, the etiologic agent of canine tropical pancyto- ...
5
Sequential Evaluation of Dogs Naturally Infected withEhrlichia canis, Ehrlichia chaffeensis,Ehrlichia equi, Ehrlichia ewingii, orBartonella vinsonii
... to Ehrlichia canis antigens by indirect immunoflu- orescent antibody testing have been attributed to infection with either ...four Ehrlichia species: E. canis, E. chaffeensis, ...three ...
7
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection
... ABSTRACT Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear ...E. chaffeensis in- fection of the host cell and evasion of host defenses are not fully ...
14
Isolation and characterization of a new strain of Ehrlichia chaffeensis from a patient with nearly fatal monocytic ehrlichiosis
... Ehrlichia chaffeensis is the causative agent of human monocytic ehrlichiosis, a disease that ranges in severity from asymptomatic infection to ...E. chaffeensis has been made, the Arkansas strain, ...
8
Molecular Characterization of Antibody Epitopes of Ehrlichia chaffeensis Ankyrin Protein 200 and Tandem Repeat Protein 47 and Evaluation of Synthetic Immunodeterminants for Serodiagnosis of Human Monocytotropic Ehrlichiosis
... of Ehrlichia chaffeensis, TRP32, TRP47, and TRP120, have been identified and molecularly characterized within tandem repeat (TR) ...E. chaffeensis 200-kDa ankyrin protein (Ank200) and the minor ...
11
Serological responses to Ehrlichia equi, Ehrlichia chaffeensis, and Borrelia burgdorferi in patients from New York State
... The Ehrlichia equi-like agent of HGE is transmitted by the black-legged tick (Ixodes scapularis; also called the deer tick), which may also transmit Borrelia burgdorferi and Babesia microti (19, 20, 23, 27, ...for ...
8
Characterization of the Major Antigenic Protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and Its Application for Serodiagnosis of Ehrlichiosis
... by Ehrlichia canis or Ehrlichia chaffeensis, can result in clinical disease in naturally infected ...E. chaffeensis and ...E. chaffeensis would cross-react with ...E. chaffeensis ...
5
Isolation of Ehrlichia chaffeensis from wild white tailed deer (Odocoileus virginianus) confirms their role as natural reservoir hosts
... Ehrlichia chaffeensis was isolated from the blood of five deer in DH82 cell cultures, including two deer that were PCR neg- ...E. chaffeensis antiserum, (iv) generation of expected 389-bp PCR ...
6
Ehrlichia chaffeensis and Its Invasin EtpE Block Reactive Oxygen Species Generation by Macrophages in a DNase X Dependent Manner
... pathogen Ehrlichia chaffeensis lacks most genes that confer resistance to oxidative stress but can block reactive oxygen species (ROS) generation by host ...cells, Ehrlichia uses the C ter- minus of ...
14
Ehrlichia chaffeensis Proliferation Begins with NtrY/NtrX and PutA/GlnA Upregulation and CtrA Degradation Induced by Proline and Glutamine Uptake
... bacterium Ehrlichia chaffeensis begins to replicate upon entry into human mono- cytes is poorly ...E. chaffeensis PutA and GlnA complemented Escherichia coli putA and glnA ...E. chaffeensis ...
11
Use of Peptide Based Enzyme Linked Immunosorbent Assay followed by Immunofluorescence Assay To Document Ehrlichia chaffeensis as a Cause of Febrile Illness in Nicaragua
... Ehrlichia chaffeensis, the etiologic agent of human monocytic ehrlichiosis (HME), has been extensively studied as a cause of acute febrile illness and an emerging tick-borne zoonosis in the United ...E. ...
5
Ehrlichia chaffeensis TRP120 Activates Canonical Notch Signaling To Downregulate TLR2/4 Expression and Promote Intracellular Survival
... ABSTRACT Ehrlichia chaffeensis preferentially targets mononuclear phagocytes and survives through a strategy of subverting innate immune defenses, but the mechanisms are ...E. chaffeensis type 1 ...
15
Major Species-Specific Antibody Epitopes of the Ehrlichia chaffeensis p120 and E. canis p140 Orthologs in Surface-Exposed Tandem Repeat Regions
... E. chaffeensis p120 repeat unit by ...E. chaffeensis p120 repeat unit. (B) E. chaffeensis p120 peptides reacted with the ...anti-E. chaffeensis dog serum derived from an experimentally ...
9
Molecular Variation in the Variable Length PCR Target and 120 Kilodalton Antigen Genes of Ehrlichia chaffeensis from White Tailed Deer (Odocoileus virginianus)
... E. chaffeensis having the four-repeat variant and none were infected with the six-repeat variant; however, we detected a WTD infected with the six-repeat variant in Florence County, ...
5