Electrospray-ionization
Expanded Newborn Screening for Inborn Errors of Metabolism by Electrospray Ionization-Tandem Mass Spectrometry: Results, Outcome, and Implications
... Methods. During the period of study, 250 000 neo- nates in a German population were investigated for 23 inborn errors of metabolism by electrospray ionization- MS/MS. The overall value of the screening ...
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Enantioselective discrimination of amino acids and hexose monosaccharides in gas phase using electrospray ionization mass spectrometry
... The thesis entitled “ Enantioselective discrimination of amino acids and hexose monosaccharides in gas phase using electrospray ionization mass spectrometry ” is divided into three cha[r] ...
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A Mass Spectrometric Study of Kratom Compounds by Direct Infusion Electrospray Ionization Triple Quadrupole Mass Spectrometry
... With the assistance of direct infusion electrospray ionization mass spectrometry technique, mass spectra and in- formation such as molecular weight and mass fragment were obtained. Possible cleavage and ...
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Reverse Transcription PCR–Electrospray Ionization Mass Spectrometry for Rapid Detection of Biothreat and Common Respiratory Pathogens
... Electrospray ionization mass spectrometry. RT-PCR products were analyzed with the Ibis T5000 universal biosensor platform (Ibis Biosci- ences, Inc., Carlsbad, CA). Each PCR mixture underwent an automated ...
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Fast Detection of Volatile Organic Compounds from Bacterial Cultures by Secondary Electrospray Ionization Mass Spectrometry
... We propose a novel application of secondary electrospray ionization-mass spectrometry (SESI-MS) as a real-time clinical diagnostic tool for bacterial infection. It is known that volatile organic compounds ...
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Advancements in Infrared Matrix Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Instrumentation and Methodology.
... 49 methods, which typically require several minutes of analysis time per sample. 5 In addition, most MS-based methodologies are susceptible to the presence of nonvolatile compounds such as salts, buffers, and detergents ...
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Enhanced Diagnostic Yields of Bacteremia and Candidemia in Blood Specimens by PCR Electrospray Ionization Mass Spectrometry
... tect microbes utilizing PCR do so by directly detecting and ampli- fying microbial nucleic acids that are present in the blood (14, 15). A recently developed molecular detection method analyzes the PCR amplification ...
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Rapid Detection and Molecular Serotyping of Adenovirus by Use of PCR Followed by Electrospray Ionization Mass Spectrometry
... We have developed a PCR/electrospray ionization mass spectrometry (PCR/ESI-MS) assay for the rapid detection, identification, and serotyping of human adenoviruses. The assay employs a high-performance mass ...
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A Hyphenation of Stripping Voltammetry with Electrospray Ionization Mass Spectrometry; an Effect of Sodium Perchlorate on Ferrocene Oxidation
... In order to gain complementary insight into the nature of the complexes formed, electrospray ionization mass spectrometry (ESI-MS) has been used to assess the types of metal complexes [17-22]. In many ...
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Chemical Fingerprinting of Counterfeits of Viagra and Cialis Tablets and Analogues via Electrospray Ionization Mass Spectrometry
... [12] A. C. L. Amorim, A. M. C. Hovell, A. C. Pinto, M. N. Eberlin, N. P. Arruda, E. J. Pereira, H. R. Bizzo, R. R. Catharino, Z. B. M. Filho and C. M. Rezende, “Green and Roasted Arabica Coffees Differentiated by ...
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Quantitative Detection of Trace Malachite Green in Aquiculture Water Samples by Extractive Electrospray Ionization Mass Spectrometry
... extractive electrospray ionization mass spectrometry (EESI-MS) has been extended to the trace detection of MG within lake water and aquiculture water, due to the intensive use of MG as a biocide in ...
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Detection of Oxidized Ferrocenes by LC MS with Electrospray Ionization Using Picric Acid as the Counter Ion
... LC-MS in ESI mode, with picrate as a counterion, was an effective means of in- vestigating the oxidation reactions of ferrocene and several of its derivatives. Oxidized ferrocenes were detected by ESI in positive mode, ...
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Development and Application of Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution Studies.
... Ambient ionization techniques such as desorption electrospray ionization (DESI) [10], liquid extraction surface analysis (LESA) [11], and matrix-assisted laser desorption electrospray ...
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SIMPLE AND ROBUST METHOD FOR THE QUANTIFICATION OF LEVONORGESTREL IN PLASMA BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ELECTROSPRAY IONIZATION MASS SPECTROMETRY
... chromatography electrospray ionization mass spectrometry (LC–ESI–MS) method is developed and validated for the quantification of Levonorgestrel in human ...
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ELECTROSPRAY IONIZATION MASS SPECTROMETRY FRAGMENTATION PATHWAYS OF SALTS OF SOME 1,2,4 TRIAZOLYLTHIOACETATE ACIDS, THE ACTIVE PHARMACEUTICAL INGREDIENTS
... Methods: The study was done in the Electrospray ionization source with single quadrupole mass spectrometer Agilent 6120 after elution through column Zorbax SB-C18, 30 mm × 4.6 mm, 1.8 µm at Agilent 1260 ...
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METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF AMPRENAVIR IN HUMAN PLASMA BY LIQUID CHROMATOGRAPHY–ELECTROSPRAY IONIZATION–TANDEM MASS SPECTROMETRY
... Vol 12, Issue 9, 2019 Online 2455 3891 Print 0974 2441 METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF AMPRENAVIR IN HUMAN PLASMA BY LIQUID CHROMATOGRAPHY?ELECTROSPRAY IONIZATION?TANDEM MASS S[.] ...
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From Solution Into the Gas Phase: Studying Protein Hydrogen Exchange and Electrospray Ionization Using Molecular Dynamics Simulation
... Here, we apply Molecular Dynamics (MD) simulations to investigate fundamental aspects of structural mass spectrometry (MS). We first examine microscopic phenomena underlying Hydrogen/Deuterium exchange (HDX). HDX ...
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Identification of Mycobacterium Species and Mycobacterium tuberculosis Complex Resistance Determinants by Use of PCR Electrospray Ionization Mass Spectrometry
... Sample analysis. Sample analysis was performed following PCR am- plification by loading the plate onto the Plex-ID system (Abbott Molecu- lar, Des Plaines, IL), where the PCR product was desalted and analyzed using ...
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Pathogen Profiling: Rapid Molecular Characterization of Staphylococcus aureus by PCR/Electrospray Ionization Mass Spectrometry and Correlation with Phenotype
... There are few diagnostic methods that readily distinguish among community-acquired methicillin (meticil- lin)-resistant Staphylococcus aureus strains, now frequently transmitted within hospitals. We describe a rapid and ...
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Matrix-Assisted Laser Desorption Electrospray Ionization: Fundamental Principles and Applications Toward Direct Analysis and Molecular Imaging.
... inception, electrospray ionization (ESI) has evolved to become one of the most widely utilized ionization techniques for the mass spectrometric analysis of ...of electrospray as a means of ...
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