endothelial cell function
Abnormal endothelial cell function in scleroderma and related conditions
... abnormal endothelial cell function in scleroderma and suggest that the endothelium may be abnormal well before the development of skin changes or internal organ ...
146
Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function
... that endothelial Tpl2 is required for multiple aspects of endothelial cell function, homeostasis and angiogenesis, therapeutic strategies based on pharmacological inhibition of Tpl2 need ...
14
Docosahexaenoic acid regulates vascular endothelial cell function and prevents cardiovascular disease
... vascular endothelial dysfunc- tion and enhance atherosclerosis [31, ...to endothelial dysfunction, including LOX-1 ...controlling cell signal transduction and altering gene ex- pression in the ...
13
Endothelial Cell Function and Dysfunction in Critically Ill Children
... lung function and modulate vascular tone, locally match perfusion to ventilation, and maintain alveolar ...EC function have been observed in ARDS, and a prevailing theory is that pulmonary microvascular ...
13
The interplay between TGF-β and VEGF signalling in endothelial cell function
... the function of ECs and vascular SMCs, affecting ...concentration, cell density, cell type, media and matrix coating may determine specific cellular responses to TGF-β family ...
177
Rapamycin impairs endothelial cell function in human internal thoracic arteries
... CPI). Cell debris was removed by centrifugation, and superna- tants were quantified by the protein assay, Precision Plus Protein Standards ...(1:500, Cell Signalling Tech- nology) for 2 h at room ...
8
Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis
... of endothelial nitric oxide synthase, increased basal and VEGF-induced cell migration and enhanced endothelial tube formation on growth factor reduced ...
8
Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition
... and endothelial cells that is likely to involve much more complex interactions than merely hypoxic tumor cell-derived VEGF acting on endothelial ...
16
NF κB regulation of endothelial cell function during LPS induced toxemia and cancer
... 1 Department of Microbiology, 2 Department of Medicine, and 3 Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York, USA. The transcription factor NF-κB is an important ...
10
A Stromal Cell-Derived Factor 1α Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome
... barrier function were ...vascular endothelial (VE)-cadherin cell surface expression and expansion of the intercellular ...improves endothelial barrier integrity through increased ex- pression ...
9
Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function
... islet function associated with the develop- ment of ...islet endothelial cells (ECs) and (ii) islet mesenchymal stromal cells (MSCs) ...anti-angiogenic function of Eng expressing MSCs in islets but ...
6
Original Article Effect of miR-200b on retinal endothelial cell function under high glucose environment
... retinal endothelial cell, resulting in retinal structure and function ...specific function and mechanism have not been eluci- ...retinal endothelial cells (hRECs) under high glucose ...
6
Taurine Protects Gut Barrier Function and Prevents Endothelial Cell Injury Induced by Ischaemia Reperfusion
... on endothelial cell function and ...I/R-induced endothelial cell injury by reduced anti-oxidant activ- ity and modulation of eNOS expression and intracellular calcium ...
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Effects of Niacin and Vitamin D on Endothelial Cell Angiogenic Function and Vascular Regeneration During Lipotoxicity
... improve endothelial functions and vascular regeneration following vascular injury, however, it appears vitamin D may promote or inhibit neovascularization in a context-dependent ...improve endothelial ...
119
Endothelial function in migraine: a cross-sectional study
... i.e endothelial-independent vasodila- tion, was impaired while acetylcholine-induced release of NO was intact, the authors hypothesized that vascular smooth muscle cell, but not endothelial ...
8
Inhibition of platelet function by an aspirin insensitive endothelial cell ADPase Thromboregulation by endothelial cells
... J Clin Invest. 1991;88(5):1690-1696. https://doi.org/10.1172/JCI115485. We previously reported that platelets become unresponsive to agonists when stimulated in combined suspension with aspirin-treated human umbilical ...
8
Endothelial transplantation rejuvenates aged hematopoietic stem cell function
... sickle cell disease, that could ben- efit from autologous transplantation of the patient’s own gene-cor- rected ...BM cell numbers that are suboptimal for achieving robust ...HSCT cell dose could ...
17
Homocysteine and endothelial function
... on endothelial function, thrombomodulin surface expression* protein C activation*tissue factor activity*^* and on susceptibility of low-density lipoproteins to oxidation*^® have all been described as ...
178
Effects of Ebola Virus Glycoproteins on Endothelial Cell Activation and Barrier Function
... cause endothelial cell destruction, the role of the soluble glycoproteins in pathogenesis is largely unknown; however, they are hypothesized to be of biological relevance in terms of target cell ...
9
The endothelial cell ecto ADPase responsible for inhibition of platelet function is CD39
... to endothelial cells, they become unresponsive to agonists (Marcus, ...of endothelial cells which metabolizes ADP released from activated platelets, resulting in blockade of the aggregation ...vein ...
11