endothelin-1 (1–31)
Plasmatic Biochemical Variables Associated with Polymorphisms in the Endothelin-1 and Endothelin-1 Receptor a Genes in Hypertensive Patients: Pilot Study
... Results: For the polymorphisms of Receptor A from Endothelin -1 studied the presence of cytosine homozygous genotype was less frequent in males (P = .02). For both genders, the same genotype was associated ...
8
Prevention of Inflammation-Associated Preterm Birth by Knockdown of the Endothelin-1-Matrix Metalloproteinase-1 Pathway
... of endothelin-1 (ET-1) ac- tion through the use of an endothelin-converting enzyme-1 (ECE-1) inhibitor, an established commercially available endothelin receptor ...
8
Endothelin 1/endothelin B receptor–mediated increases in NHE3 activity in chronic metabolic acidosis
... the endothelin-B (ET B ) receptor increases NHE3 ...M endothelin-1 (ET-1) increased NHE3 activity, but this treatment had no effect on tubules from Tg/Tg:ET B –/– ...
8
Neural peptidase endothelin converting enzyme 1 regulates endothelin 1–induced pruritus
... diseases. Endothelin 1 (ET-1) evokes histamine-independent pruritus in mammals through activation of its cognate G protein–coupled receptor endothelin A receptor ...enzyme 1 ...
14
Role of Endothelin 1/Endothelin A receptor mediated signaling pathway in the aortic arch patterning in mice
... derivatives. Endothelin-1 (ET-1) is proteolytically generated from its inactive precursor by endothelin-converting enzyme-1 (ECE-1) and acts on the endothelin-A (ETA) ...
13
Endothelin 3 induces hypertrophy of cardiomyocytes by the endogenous endothelin 1 mediated mechanism
... that endothelin-1 (ET-1) mediates angiotensin II-induced hypertrophy of cardiomyocytes as an autocrine/paracrine ...whether endothelin-3 (ET-3) induces hypertrophy of cultured neonatal rat ...
8
Expression and localization of endothelin 1 and endothelin receptors in human meningiomas Evidence for a role in tumoral growth
... antagonist of ET-Br, did not block the proliferative effect of ET-1. In conclusion, our data provide evidence that ET-1 constitutes an important growth factor for meningiomas acting via ET-Ar. We can ...
10
Modulation of the Cardiomyocyte Hypertrophic Responses to Endothelin-1 by Adipocytes
... It has been two decades since studies linked cardiac hypertrophy and heart failure. Cardiac hypertrophy is an independent risk factor for myocardial infarction, angina pectoris, arrhythmia and cardiac sudden death (Levy ...
158
Role of endothelin-1 in lung disease
... The cellular source of ET-1 in lung allografts is unknown. The expression of ET-1 in nontransplanted human lungs is low and found primarily in the vascular endothelium [114]. Transbronchial biopsy specimens ...
12
Endogenous endothelins mediate increased distal tubule acidification induced by dietary acid in rats
... higher endothelin-1 addition to renal interstitial fluid than those given distilled H2O (480+/-51 ...B-type endothelin receptors had higher HCO3 secretion than baseline (NH4)2SO4 animals ...A-type ...
10
Verotoxin and ricin have novel effects on preproendothelin 1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium
... (VTs) 1 and 2 (Shiga toxin 1 and 2) with vascular en- dothelium is believed to play a central role in the pathogen- esis of the thrombotic microangiopathy and ischemic lesions characteristic of hemolytic ...
12
Endothelin-Converting Enzyme-1 (ECE-1) Is Post-Transcriptionally Regulated by Alternative Polyadenylation
... active endothelin-1 (ET-1), a mitogenic peptide implicated in the aetiology of a number of diseases, including ...the endothelin axis. Here we provide evidence that the expression of ...
8
Changes in vasoactive pathways in congenital diaphragmatic hernia associated pulmonary hypertension explain unresponsiveness to pharmacotherapy
... the endothelin A (ETA) and B (ETB) receptors in human CDH as well as in the nitrofen rat model [6, ...7]. Endothelin-1 (ET-1) is a potent vasoconstrictor [8] and is increased in lung tissue of ...
12
Ontogeny of endothelins 1 and 3, their receptors, and endothelin converting enzyme 1 in the early human embryo
... deficient migration/proliferation/differentiation of neural crest cells, i.e., neurocristopathies. To bring new insight about the exact roles of ETs in development and the involvement of neural crest cells in these ...
12
LANGUAGE DEVELOPMENT. 31 1boks ,.1)!
... French taught at Culham as L3 is introduced in Year 2 and is assessed via a combination of formative and summative tests which focus upon vocabulary acquisition and grammatical knowled[r] ...
274
Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure
... this study reproduced some of the findings that led to its initial hypothesis. as previously described in similar models [3-5], the Et system was strongly acti- vated, and a significant correlation between plasma ...
5
Volume 31 - Article 1 | Pages 1–26
... The binary regressions for the main variables indicated that, after other factors are controlled for, mothers who were older and whose youngest child was older were less likely to report the intention to have another ...
28
Endothelin and endothelin converting enzyme 1 in the fish gill: evolutionary and physiological perspectives
... While searching the completed genome projects, we were unable to find EDN orthologues in any organism basal to the teleost fishes. From the maximum likelihood analyses presented in Fig.·1, there are three distinct ...
12