Epstein-Barr
Membrane Anchoring of Epstein Barr Virus gp42 Inhibits Fusion with B Cells Even with Increased Flexibility Allowed by Engineered Spacers
... the Epstein-Barr virus (EBV) fusion-triggering complex consisting of the EBV B cell receptor human leukocyte antigen (HLA) class II and the EBV-encoded proteins gp42 and ...
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The Epstein-Barr virus latent membrane protein 1 regulates gene expression by engaging multiple signaling pathways
... Epstein-Barr virus (EBV) is a ubiquitous human gammaherpesvirus that is associated with a variety of human malignancies of lymphoid and epithelial origins, such as post- transplant lymphoproliferative ...
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Purification of the Epstein-Barr virus-determined nuclear antigen from Epstein-Barr virus-transformed human lymphoid cell lines.
... Purification of the Epstein-Barr Virus-Determined Nuclear Antigen from Epstein-Barr Virus-Transformed Human Lymphoid Cell Lines JANOS LUKA,$ TOMAS LINDAHL,t AND GEORGE KLEIN Departments [r] ...
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Epstein Barr viral microRNAs target caspase 3
... The Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that transforms B cells and causes several malignancies including Burkitt ’ s lymphoma. EBV differentially expresses at least 49 mature microRNAs ...
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The Cytoplasmic Tail Domain of Epstein Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment
... ABSTRACT Epstein-Barr virus (EBV) is associated with infectious mononucleosis and a variety of cancers as well as lymphopro- liferative disorders in immunocompromised ...
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A study of Epstein Barr virus infection in the Chinese tree shrew(Tupaia belangeri chinensis)
... In this study, tree shrews (Tupaia belangeri chinensis) were used to establish an animal model of natural EBV infection. Tree shrews aresmall animals that are closely related to primates and live in tropical and ...
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Valpromide Inhibits Lytic Cycle Reactivation of Epstein Barr Virus
... Valpromide Inhibits Lytic Cycle Reactivation of Epstein Barr Virus Valpromide Inhibits Lytic Cycle Reactivation of Epstein Barr Virus Kelly L Gorres,a* Derek Daigle,a Sudharshan Mohanram,a Grace E McI[.] ...
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Epstein Barr virus infected T lymphocytes in Epstein Barr virus associated hemophagocytic syndrome
... Abbreviations used in this paper: BM, bone marrow; EA, early antigen; EBNA, Epstein-Barr nuclear antigen; EBV-AHS, Epstein-Barr virus-associated hemophagocytic syndrome; MNC, mononuclear[r] ...
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Detection of Epstein-Barr virus (EBV) in human lymphoma tissue by a novel microbial detection array
... the Epstein-Barr virus (EBV), are associated with 10-15% of B-cell lymphomas and are found at a higher frequency in immunosuppressed ...for Epstein-Barr virus-encoded small RNA (EBER+), while ...
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Identification and nucleotide sequences of two similar tandem direct repeats in Epstein-Barr virus DNA.
... 3 Identification and Nucleotide Sequences of Two Similar Tandem Direct Repeats in Epstein-Barr Virus DNA Received 14 June 1982/Accepted 16 August 1982 Epstein-Barr virus DNA is known to [r] ...
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Changes in Expression Induced by Epstein Barr Virus LMP1 CTAR1: Potential Role of bcl3
... The Epstein-Barr virus protein latent membrane protein 1 (LMP1) has two NF-B activating domains within its in- tracellular carboxy terminus (carboxy-terminal activating region 1 [CTAR1] and ...
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First Days in the Life of Naive Human B Lymphocytes Infected with Epstein Barr Virus
... ABSTRACT Epstein-Barr virus (EBV) infects and activates resting human B lympho- cytes, reprograms them, induces their proliferation, and establishes a latent infection in ...only Epstein- Barr ...
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Epstein-Barr Virus Encodes a Novel Homolog of the bcl-2 Oncogene That Inhibits Apoptosis and Associates with Bax and Bak
... Gammaherpesviruses produce Bcl-2 protein homologs (v- Bcl-2s) (9, 13, 29, 33) that are hypothesized to contribute to immune evasion and to promote tumorigenesis by preventing apoptosis in response to either virus ...
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Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.
... In contrast, the cells infected with the P3HR1 Epstein-Barr virus strain, a deletion mutant that cannot encode Epstein-Barr nuclear antigen 2 EBNA2 or a full-length EBNA-LP, expressed EB[r] ...
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Case Report Epstein-Barr virus-associated NK-cell lymphoproliferative disorder treated with haploidentical hematopoietic stem cell transplantation
... Abstract: Epstein-Barr virus (EBV) is a ubiquitous herpes virus whose infection is usually asymptomatic and persists for a lifetime. It often causes symptomatic diseases, such as infectious mononucleosis ...
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Antibody to the Rheumatoid Arthritis Nuclear Antigen: ITS RELATIONSHIP TO IN VIVO EPSTEIN BARR VIRUS INFECTION
... nuclear antigen was present in 26 (50%) of these. In 67 sequential sera from 11 college-age students with infectious mononucleosis who became positive for antibody to rheumatoid arthritis nuclear antigen, only 2 were ...
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Epstein Barr Virus—The Cause of Multiple Sclerosis
... of Epstein- Barr Virus (EBV) infections in the pathogenesis of Multiple Sclerosis ...with Epstein-Barr Virus (EBV) and the occurrence of Mul- tiple Sclerosis (MS) ...
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Epstein Barr virus and cytomegalovirus infections and their clinical relevance in Egyptian leukemic pediatric patients
... It is now known that Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infect about 90% of the popu- lation globally, and that infection continues in a latent phase [1]. Viral infections, particularly ...
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Healthy rabbits are susceptible to Epstein Barr virus infection and infected cells proliferate in immunosuppressed animals
... Background: Epstein-Barr virus (EBV) is an oncogenic virus implicated in the pathogenesis of several human malignancies. However, due to the lack of a suitable animal model, a number of fundamental ...
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Genomic Diversity of Epstein-Barr Virus Genomes Isolated from Primary Nasopharyngeal Carcinoma Biopsy Samples
... Undifferentiated nasopharyngeal carcinoma (NPC) has a 100% association with Epstein-Barr virus (EBV). However, only three EBV genomes isolated from NPC patients have been sequenced to date, and the role of ...
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