ESCRT-I
Role of ESCRT-I in Retroviral Budding
... an ESCRT-I subunit, Tsg101, a component of the class E vacuolar protein sorting (VPS) machinery, is required for the budding of viruses, such as human immunodeficiency virus type 1 (HIV-1) and Ebola virus, ...
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Role of Viral RNA and Co-opted Cellular ESCRT-I and ESCRT-III Factors in Formation of Tombusvirus Spherules Harboring the Tombusvirus Replicase
... mammals) ESCRT-I in combination with Bro1p in tombusvirus ...recruits ESCRT-III factors to facilitate formation of ILVs in the late endosomes as well as HIV budding out of the infected cells ...of ...
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A Unique N-Terminal Sequence in the Carnation Italian ringspot virus p36 Replicase-Associated Protein Interacts with the Host Cell ESCRT-I Component Vps23
... (ESCRT). ESCRT is comprised of a series of protein subcomplexes (i.e., ESCRT-0 -I, -II, and -III) that normally participate in late endosome biogene- sis and some of which are also hijacked by ...
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Distinct Roles of Cellular ESCRT-I and ESCRT-III Proteins in Efficient Entry and Egress of Budded Virions of Autographa californica Multiple Nucleopolyhedrovirus
... of ESCRT-III in efficient egress of ...of ESCRT-I and ESCRT-III components in AcMNPV entry, we could not use the same viral complementation system to study the role of these ESCRT ...
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Nonstructural Protein 3 of Bluetongue Virus Assists Virus Release by Recruiting ESCRT-I Protein Tsg101
... protein (5, 71, 78). Using yeast two-hybrid technology, we have recently identified the p11 subunit of the cellular calpactin complex as a cellular binding partner of NS3 (6). Even though the exact physiological role of ...
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Ubiquitin conjugation to Gag is essential for ESCRT mediated HIV 1 budding
... The ESCRT-I component TSG101 binds directly to PTAP motifs within the HIV-1 Gag protein and eliminating the PTAP motif or the ability of TSG101 to bind Gag reduces viral release by ...other ...
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ESCRT requirements for EIAV budding
... the ESCRT-I complex through a direct interaction with the Vps23p/ TSG101 sub- unit ...[15]. ESCRT-I recruits ESCRT-II, and the ESCRT-I-II supercomplex helps stabilize the ...
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The Interferon-Induced Gene ISG15 Blocks Retrovirus Release from Cells Late in the Budding Process
... linking ESCRT proteins to the C terminus of ASLV Gag/ ⌬ p2b did not negate ISG15 ...the ESCRT-I protein, Vps37C, or the ESCRT-III protein, CHMP6, to the C terminus of HIV-1 Gag/P7L did not ...
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Aspergillus nidulans Ambient pH Signaling Does Not Require Endocytosis
... of ESCRT complexes, which have a key role in multivesicular body (MVB) sorting in endo- somes, led to a model in which the pH-sensing module and the ESCRT-associated proteins would be spatially separated, ...
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Sprouty 2 Binds ESCRT-II Factor Eap20 and Facilitates HIV-1 Gag Release
... overall ESCRT-III function. Such disruption of overall ESCRT-III function would negatively impact HIV release and possibly offset any detectable effects of Eap20 ...of ESCRT-I is bypassed with ...
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ESCRT function in cytokinesis : location, dynamics and regulation by mitotic kinases
... of ESCRT proteins in plants is restricted to only a few ...all ESCRT components across tissues and stages of plant development ...of ESCRT function in cytokinesis in plants have been limited to the ...
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The Structural Biology of HIV Budding and Maturation
... the ESCRT pathway in MVB biogenesis and viral budding are also likely driven by a "dome" ...to ESCRT-0, -I, or –II, but CdvA performs the same function of recruiting ESCRT-III to the ...
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Treptow, Till (2009): Identifizierung und Charakterisierung zweier neuer Proteine, die mit dem HIV-Rev-Protein interagieren. Dissertation, LMU München: Fakultät für Biologie
... im ESCRT-I Komplex und die Kontaktierung von ESCRT-II über VPS 28, siehe ...der ESCRT-Maschinerie erfüllen kann ...des ESCRT-I Komplexes durch den ESCRT-II Komplex ...
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Ubpy controls the stability of the ESCRT 0 subunit Hrs in development
... Hrs was stable (supplementary material Fig. S5B). However, Hrs accumulation was greatly reduced when Ubpy was depleted by RNAi (Fig. 3K). Interestingly, this Ubpy RNAi-mediated Hrs degradation is independent of Hrs ...
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Human Cytomegalovirus Exploits ESCRT Machinery in the Process of Virion Maturation
... with ESCRT machinery, with different pathways important in different ...HCMV- ESCRT interactions. A model of exploitation of ESCRT ma- chinery by HCMV is proposed ...in ESCRT recruitment. ...
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A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe
... that ESCRT genes are required for cytokinesis and cell separation in fission ...individual ESCRT gene deletions, and a deletion mutant of clp1 (clp1D) and temperature sensitive mutants of plo1 and ark1 ...
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The Candida albicans ESCRT Pathway Makes Rim101-Dependent and -Independent Contributions to Pathogenesis
... Since ESCRT-I, ESCRT-II, and ESCRT-III mutants have more severe growth defects than do ESCRT-0 and ESCRT-DS mutants, this suggests that the ESCRT pathway contributes to ...
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The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis
... the ESCRT I-III protein sorting ...the ESCRT I-III complexes are found in the Arabidopsis genome, indicating that the mono- ubiquitin-dependent vacuolar protein degradation pathway is ...
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Intervention of Bro1 in pH-Responsive Rim20 Localization in Saccharomyces cerevisiae
... for ESCRT subunits, localizations of Bro1 and Rim20 have distinct genetic require- ...of ESCRT-I with endosomes but is not required for Rim101 processing (4, 9, ...
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The Ancient Small GTPase Rab21 Functions in Intermediate Endocytic Steps in Trypanosomes
... of ESCRT-I (endosomal sorting complex required for transport-I) and is required for the recognition and sorting of ubiquitinated cargo ...and ESCRT-mediated pathways (18), we assessed whether ...
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