eukaryotic translation initiation
Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
... and eukaryotic initiation factor 2 in heme-deficient or double- residues within the ε-subunit of eukaryotic translation initiation stranded RNA-inhibited reticulocyte ...
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Insights into Eukaryotic Translation Initiation from Mass Spectrometry of Macromolecular Protein Assemblies
... of Eukaryotic Translation Initiation In the last decade, MS techniques have success- fully contributed to provide insights into the structures of eIFs, their interactions with other proteins and ...
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Functional role of eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) in NSCLC
... Received: January 26, 2016 Accepted: March 02, 2016 Published: March 18, 2016 ABSTRACT Eukaryotic translation initiation factor 4 gamma 1(EIF4G1) is related to tumorigenesis and tumor progression. ...
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Recent insights into eukaryotic translation initiation factors 5A1 and 5A2 and their roles in human health and disease
... The eukaryotic translation initiation factor 5A1 (eIF5A1) and its homolog eIF5A2 are the only two human proteins containing the unique post‑translational modification–hypusination, which is essential ...
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Efficient Translation of Rotavirus mRNA Requires Simultaneous Interaction of NSP3 with the Eukaryotic Translation Initiation Factor eIF4G and the mRNA 3′ End
... the eukaryotic translation initiation factor ...efficient translation of virus-like ...mRNA translation by NSP3 was also observed in a rabbit reticulocyte lysate translation ...
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Eukaryotic translation initiation factor 4All contributes to microRNA 122 regulation of hepatitis C virus replication
... HCV RNA interaction. Finally, we show that eIF4AI deple- tion relieves the inhibition of HCV replication by eIF4AII or CNOT1 knockdown, suggesting eIF4AII and CNOT1 are only required for HCV replication when eIF4AI is ...
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Incorporation of Eukaryotic Translation Initiation Factor eIF4E into Viral Nucleocapsids via Interaction with Hepatitis B Virus Polymerase
... The DNA genome of hepatitis B virus (HBV) replicates via reverse transcription within capsids following the encapsidation of an RNA template, the pregenomic RNA (pgRNA). We previously demonstrated that the 5 ⴕ cap ...
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Eukaryotic translation initiation factor 5A2 (eIF5A2) regulates chemoresistance in colorectal cancer through epithelial mesenchymal transition
... cancer. Eukaryotic translation initiation factor 5A2 (eIF5A2), one of the two isoforms in the eIF5A family, has been reported to be a new oncogene in many types of human ...
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Upregulation of a novel eukaryotic translation initiation factor 5A (eIF5A) in dengue 2 virus infected mosquito cells
... novel eukaryotic translation initiation factor 5A (eIF5A) which is upregulated in Aedes albopictus-derived C6/36 cells infected by the type 2 dengue (Den-2) ...
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Eukaryotic translation initiation factor 2B beta (eIF2B β), a new class of plant virus resistance gene
... Publisher’s statement: "This is the peer reviewed version of the following article: Jannat, Shopan, Mou, Haipeng, Zhang, Lili, Zhang, Changtong, Ma, Weiwei, Walsh, John A., Hu, Zhongyuan, Yang, Jinghua and Zhang, ...
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Elevated expression of eukaryotic translation initiation factor 3H is associated with proliferation, invasion and tumorigenicity in human hepatocellular carcinoma
... Aim: We studied the role of eukaryotic translation initiation factor 3 subunit H (EIF3H) in hepatocellular carcinoma (HCC) progression. Results: High EIF3H expression was observed in 50.23% patients. ...
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Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes
... SUMMARY The ENU-induced repro8 mutation was identified in a screen to uncover genes that control mouse gametogenesis. repro8 causes male-limited infertility, with failure of spermatocytes to exit meiotic prophase via the ...
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Review Article Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eif5a) for Prognosis and Treatment of Hepatocellular Carcinoma
... eukaryotes, translation of messenger RNA (mRNA) to protein is a key process in protein biosynthesis in which initiation of translation involves interaction of different eukaryotic ...
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Influenza A Virus-Induced Degradation of Eukaryotic Translation Initiation Factor 4B Contributes to Viral Replication by Suppressing IFITM3 Protein Expression
... mRNA translation/protein expression by eukaryotic translation initiation factors may enhance our understanding of innate immune re- sponse to influenza virus ...
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Eukaryotic translation initiation factor 3B accelerates the progression of esophageal squamous cell carcinoma by activating β-catenin signaling pathway
... carcinoma, eukaryotic translation initiation factors 3B, β-catenin signaling pathway Received: October 22, 2015 Accepted: April 28, 2016 Published: May 30, 2016 AbstrAct Introduction: Esophageal ...
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Investigating the role of SUMOylation of eukaryotic translation initiation factors
... 4E-BP Family The eIF4E binding proteins (4E-BPs) are key regulators of protein synthesis. 1-3 As their name suggests, they function by interacting with eIF4E. This inhibits eIF4E function by prevent- ing it from ...
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The Eukaryotic Translation Initiation Factor 4GI Is Cleaved by Different Retroviral Proteases
... cap-dependent translation through cleav- age of the translation initiation factor eIF4G without affecting IRES-driven translation with mRNAs having the 5⬘ leader of ...cap-dependent ...
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Collybistin and gephyrin are novel components of the eukaryotic translation initiation factor 3 complex
... local translation and synaptic plasti- city in dendrite ...synaptic translation and in the pathophysiology of diseases associated with mutations in these ...
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Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation.
... translation approximately sevenfold (Fig. 6C). Overexpression of Paip1 isoforms had no effect on Renilla mRNA levels (Fig. 6D). Thus, the p45 isoform of Paip1 is a more potent transla- tional enhancer than the p65 ...
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Visualising ribosome profiling and using it for reading frame detection and exploration of eukaryotic translation initiation
... to initiation of transcription at alternative starts (see Supplemental Table 1 in Appendix ...the translation of additional transcripts whose sequences are not included in the RefSeq ...
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