expression signatures
Systematic analysis of expression signatures of neuronal subpopulations in the VTA
... Gene expression profiling across various brain areas at the single-cell resolution enables the identification of molecular markers of neuronal subpopulations and comprehensive characterization of their functional ...
9
Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis
... gene expression of specific immune regulatory cytokines in peripheral blood mononuclear cells (PBMC) and the presence of severe sepsis in patients with infection ...differential expression were most closely ...
9
Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells
... experimental systemic lupus erythematosus (SLE) [10]. In human autoimmunity, biopsy samples from tissues such as rheumatoid synovium [6,9] and skin [7] have yielded disease insights. Other groups of investigators have ...
9
Autoantibodies to the NY-ESO-1 Tumor Antigen in Metastatic Melanoma: Sialylation of the Fc Region of Immunoglobulin G Induces Differential Expression Signatures of Inflammatory Molecules During Dendritic Cell Differentiation and Maturation
... protein expression in human DC differentiation and maturation induced by the unique glycan structure within populations of IgG antibodies from patients with metastatic ...unique signatures will be useful in ...
18
Expression signatures and roles of microRNAs in inflammatory breast cancer
... the expression of some miRNAs is related to many diseases closely, especially in tumors, and the expression is also restricted to specific tissues or biological stages of ...their expression [36, ...
15
An integration of complementary strategies for gene expression analysis to reveal novel therapeutic opportunities for breast cancer
... the expression signatures and the patient data were based on multiple platforms, all these signatures were consol- idated to the Affymetrix HG-U133A platform by using Chip- ...metagene ...
10
Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients
... protein expression and compositional differences between microenvironment ...TWIST-overexpression signatures and shares features of claudin-low breast ...with expression of TGF-b induced fibroblast ...
12
Immature cell populations and an erythropoiesis gene expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis
... gene-expression signatures that allowed the dis- tinction between patients with new-onset sJIA and healthy controls ...several signatures were apparent, the most robust gene-expression ...
13
Original Article Using gene set enrichment analysis to identify new genes involved in sepsis-induced myopathy
... gene expression signatures and gene expression signatures from 107 siRNA- mediated knockdowns were analyzed using a rank-based algorithm to evaluate the ...PSIP1 expression was ...
10
Discovering Pathway And Cell Type Signatures In Transcriptomic Compendia With Machine Learning
... Machine learning applied to transcriptomic compendia reveals interesting substructures in high-dimensional data that often represent cell type and pathway signatures. Both supervised and unsupervised machine ...
208
A miRNA expression signature that separates between normal and malignant prostate tissues
... as expression signatures to correctly separate between the normal and malignant ...larger expression signature, including 30 miRNAs, and the analysis revealed that 16 out of 19 malignant sam- ples ...
10
Forced swim test induces divergent global transcriptomic alterations in the hippocampus of high versus low novelty-seeker rats
... depressive-like status in the second FST session. At 24 h following the second FST session, HR and LR rats (stressed and unstressed controls) were sacrificed and hippocampal samples were independently analyzed on whole ...
13
Quantitative Assessment of WT1 Expression by Real Time Quantitative PCR in Pediatric Patients with Acute Myeloblastic Leukemia
... microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B ...
7
Next generation sequencing based expression profiling identifies signatures from benign stromal proliferations that define stromal components of breast cancer
... gene expression profiling on a spectrum of fi- broblastic ...the expression profiling of archival, FFPE tissue, termed 3SEQ (3′end RNA sequencing), which we have previously ...gene expression ...
11
Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells
... gene expression signatures that differentiate the dis- ease state from healthy controls are the availability of samples, sample size, heterogeneous data sets, and ...gene expression signature derived ...
10
Brain trauma elicits non-canonical macrophage activation states
... heterogeneous expression of both inflammatory M1 and wound healing M2 markers [6–8, 17, ...gene expression could also be an average of microglia, macrophages, neutrophils, and other cells) or a more ...
12
Efficient Fully Structure-Preserving Signatures for Large Messages
... Structure-preserving signatures are pairing-based signatures where verification keys, messages and signatures all consist solely of group elements and the ver- ification algorithm relies on generic ...
22
The genetic mechanism of selfishness and altruism in parent-offspring coadaptation
... The double-stranded RNA was injected in the abdomen of mothers and offspring on day 4 after the nymphs hatched. The knockdown effects were initially validated with RT-qPCR after injection using three technical replicates ...
12
MicroRNA expression profiling of male breast cancer
... Although our tumor samples were partially microdissected, contamination with surrounding stromal tissue is inevitable. For this reason we performed an enrichment analysis of our data considering the amount of tumor ...
10
Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse model
... epigenetic signatures might be also at least partly responsible for the later development of pulmon- ary hypertension and the increased susceptibility to re- spiratory tract ...epigenetic signatures at NOS3 ...
12