F-Actin
Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin Integrity in Chlamydomonas
... When F-actin is lost either by ida5 mutation or by treatment of wild-type cells with LatB, Chlamydomonas cells respond by massively upregulating NAP1 (and, to a lesser extent, ...essential ...
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THE EFFECTS OF ELECTRICAL STIMULATION AND LASER RADIATION ON F ACTIN REORGANIZATION IN A549 AND CHO AA8 CELL LINES
... The F-actin organization and morphological changes in Chinese Hamster Ovary Cell Line (CHO AA8) after electrical ...the F-actin. The actin filaments thick bundles and multinucleated ...
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F Actin Distribution Changes Provoked by Acetaminophen in the Proximal Tubule in Kidney of Adult Male Rat
... in F-actin distribution in the proximal tubule of male Wistar ...the F-actin and was ob- served a structure in patches in the basal cytoplasm of epithelial cells of the proximal ...
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Control of tissue growth by Yap relies on cell density and F actin in zebrafish fin regeneration
... whether F-actin is involved in regulating Yap activity in vivo during regeneration, we performed intraperitoneal injections of jasplakinolide (Jasp), an inducer of F-actin polymerization and ...
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<p>TPM4 promotes cell migration by modulating F-actin formation in lung cancer</p>
... on F-actin. As a result, F-actin levels as well as fi lopodia were decreased in TPM4 knockout lung cancer cells while that were increased by overexpression of ...of F-actin was ...
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Downregulation of MYO1C mediated by cepharanthine inhibits autophagosome-lysosome fusion through blockade of the F-actin network
... the actin cytoskeleton is required for membrane fusion [32, ...an actin filament transporter that mediates actin filament movement to the cellular membrane [11, 34], we specu- lated that disruption ...
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Baculovirus VP80 Protein and the F-Actin Cytoskeleton Interact and Connect the Viral Replication Factory with the Nuclear Periphery
... specific end (the cap structure) to envelopes present in the nucleus (21). In infected cells, EGFP-VP80 was observed en- tirely in the nucleus, and the distribution pattern changed over time (Fig. 3). Initially (12 h ...
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The F actin microtubule crosslinker Shot is a platform for Krasavietz mediated translational regulation of midline axon repulsion
... of F-actin and microtubules as well as regulated ...the F-actin–microtubule crosslinker Short stop (Shot) is required for motor and sensory axon extension in the Drosophila ...
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A nanobody targeting the F actin capping protein CapG restrains breast cancer metastasis
... After immunization of a llama with human recombinant CapG, several CapG nanobodies (CAPNb) were obtained (see Materials and Methods). Because CapG regulates cytoskeletal organization through Ca 2+ -dependent inter- ...
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Modulation of F actin dynamics by maternal Mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo
... 8. F-actin cortical trenches and furrow indentations exhibit a directional progression and are associated with germ plasm ...right). F-actin arcs, associated with RNP aggregates, move outwards ...
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A Quantitative Study of Nocodazole’S Effect on HeLa Cells’ Growth Rate and F-actin Structure
... Abstract: HeLa cells were derived from human cervical cancer, which has been widely used as research model to study mammalian cell functions. In this work, nocodazole, a microtubule destabilizer, was used to treat HeLa ...
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Investigating the Role of F-Actin in Human Immunodeficiency Virus Assembly by Live-Cell Microscopy
... filamentous actin (F-actin). Large amounts of actin have been detected in HIV-1 virions, proposed to be incorporated by interac- tions with the nucleocapsid domain of the viral polyprotein ...
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Characterization of novel F actin envelopes surrounding nuclei during cleavage of a polychaete worm
... of F-actin and microtubules around nuclei from interphase to pro-metaphase in 8-cell-stage ...locate F-actin. The nucleus is surrounded by focal accumulations of F-actin ...with ...
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Loss of the F-Actin Binding and Vesicle-Associated Protein Comitin Leads to a Phagocytosis Defect
... an F-actin binding and membrane-associated protein from Dictyostelium discoideum, which is present on Golgi and vesicle membranes and changes its localization in response to agents affecting the ...
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Mcp4, a Meiotic Coiled-Coil Protein, Plays a Role in F-Actin Positioning during Schizosaccharomyces pombe Meiosis
... the F-actin complex, was visualized directly through its GFP-derived ...of F-actin and ectopically expressed ...and F-actin (red), ...of F-actin ...
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Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones
... although F-actin and microtubules together coordinately regulate axon extension/retraction, our results reveal that the early steps of translation (eIF4E-BP1 activation) occur in the absence of intact ...
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Septins Arrange F Actin Containing Fibers on the Chlamydia trachomatis Inclusion and Are Required for Normal Release of the Inclusion by Extrusion
... detect F actin, bisbenzimide Hoechst 33342 trihydrochloride (Sigma) was used to visualize host nuclei and bacterial DNA, and Sytox green nucleic acid stain (Life Technologies) was used to detect extruded ...
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Original Article Anti-tumor activity of chlorogenic acid by regulating the mTORC2 signaling pathway and disrupting F-actin organization
... of F-actin and mTORC2 (Figure 6C, 6D) confirmed CGA treatment disrupted the expression pattern of F-actin and inhibited phosphorylation of ...of F-actin organization and de- ...
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Cofilin 1-Mediated Biphasic F-Actin Dynamics of Neuronal Cells Affect Herpes Simplex Virus 1 Infection and Replication
... with actin dimers to pro- mote disassembly, which can be initiated by the activity of GSN, and cofilin 1 is considered to be primarily responsible for remod- eling the actin cytoskeleton (6, 38, ...in ...
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Original Article DSTYK knockout affects the architecture of F-actin cytoskeleton in mouse renal proximal convoluted tubules
... of F-actin cytoskeleton contributes to the pathogenesis of kidney diseases [8, ...of F-actin cytoskeleton is determined by both the polymerization dynamics of single actin fila- ments ...
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