fatty acid binding proteins
Adipocyte/macrophage fatty acid–binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice
... adipocyte/macrophage fatty acid–binding proteins (FABPs) aP2 (FABP4) and mal1 (FABP5) to examine the contribution of these lipid chaperones in macrophages and adipocytes to local and systemic ...
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Fatty acid binding proteins in brain development and disease
... polyunsaturated fatty acids (PUFAs) are critical structural components of the brain and essential for normal brain ...by fatty acid binding proteins (FABPs) which are encoded by the ...
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Adipose tissue FABP deficiency promotes metabolic reprogramming and positively impacts healthspan
... of fatty acid binding proteins to influence multiple levels of systemic regulation, we sought to provide a comprehensive profile of metabolites altered in FABP deficiency using ...amino ...
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Review: Omega-3 fatty acids transport through the placenta
... the fatty acid composition delivered to the fetus is largely determined by maternal circulating levels, the placenta preferentially transfers physiologically important long-chain polyunsaturated ...
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Phyletic distribution of fatty acid binding protein genes
... different fatty acids ...lipid-binding proteins from nematodes [26–28] have been shown to be ...contained fatty acid binding-related key residues except Val-Asp instead of ...
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Fatty acid binding protein Role in esterification of absorbed long chain fatty acid in rat intestine
... Fatty acid binding protein (FABP) is a protein of 12,000 mol wt found in cytosol of intestinal mucosa and other tissues, which exhibits high affinity for long chain fatty ...related ...
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Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells
... lipogenic proteins: ACC (acetyl-CoA carboxylase), FASN (fatty acid synthase) and SREBP1c (sterol regulatory element binding protein-1c), whereas there is no modification in DU145 and PC3 ...
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Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats
... of fatty acid metabolism, and the present results showed a higher hepatic content of TG and Tch after maternal butyrate ...related proteins in the offspring ...the fatty ...
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The changes in biomarkers for necrotising enterocolitis in premature calves with respiratory distress syndrome
... The fatty acid binding protein (FABP) family con- tains a number of cytoplasmic small size proteins with high organ ...extracellular proteins, including Claudin-3, an important sealing ...
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Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl phosphatidylinositol
... Purified membrane and soluble folate binding proteins from cultured KB cells have similar amino acid compositions and molecular weights but differ in fatty acylation.. Promoter-regulator[r] ...
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Exploring and Expanding the Fatty Acid Binding Protein superfamily in Fasciola species.
... large binding pocket, ligands of L-FABPs bind at a 2:1 molar stoichiometry ratio as opposed to 1:1 in all others examined ...of binding FAs as well as bulky ligands such as bile salts, cholesterol and haem ...
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Fatty Acid Binding Protein in Small Intestine IDENTIFICATION, ISOLATION, AND EVIDENCE FOR ITS ROLE IN CELLULAR FATTY ACID TRANSPORT
... FABP was isolated from rat intestine by gel filtration and isoelectric focusing. It showed a reaction of complete immunochemical identity with proteins in the 12,000 mol wt fatty acid- binding ...
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Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome
... element binding proteins (SREBPs) in ...cholesterol, fatty acids and triglycer- ides ...free fatty acid flux via fatty acid transport proteins ...
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Fatty acid distribution in systems modeling the normal and diabetic human circulation A 13C nuclear magnetic resonance study
... albumin, and phospholipid vesicles or native lipoproteins (all samples at pH 7.4, 37 degrees C) exhibited up to six carboxyl NMR resonances corresponding to FA bound to distinct binding sites on albumin and ...
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The adipokine fatty-acid binding protein 4 and cardiac remodeling
... Furthermore, we observed the potential beneficial correlation between FABP4 and LVMI only in patients with lower FABP4 levels but the potential harmful correlation between FABP4 and N[r] ...
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Sex Differences in Long Chain Fatty Acid Utilization and Fatty Acid Binding Protein Concentration in Rat Liver
... incorporated significantly more 14 C into glycerolipids, especially triglycerides, and into oxidation products than did male cells, per milligram cell protein. At 0.44 mM oleate, incorporation into triglycerides in ...
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Increasing medium chain fatty acids production in Yarrowia lipolytica by metabolic engineering
... In order to confirm that ELO use saturated sub- strates, we analyzed the elongation products of the strains ∆pox ∆fas and ∆pox ∆fas ∆elo1 grown with mC16:0 (Fig. 3a). Elongation of C16:0 will lead to C18:0, further ...
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System-level network analysis of nitrogen starvation and recovery in Chlamydomonas reinhardtii reveals potential new targets for increased lipid accumulation
... the fatty acid biosynthetic pathway was, in general, not present but two Acetyl-CoA-Synthetases ...of fatty acids and forming part of lipid droplets [62] were significantly accu- ...the ...
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Investigating The Regulation Of A Fatty Acid Efflux Pump In Methicillin Resistant Staphylococcus Aureus
... strain MW2 halves the MIC of palmitoleic acid, while over-expression of this gene doubles the MIC of linoleic acid (103). When we generated a deletion mutant of this gene in USA300 during this study ...
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A STUDY ON PROXIMATE CONTENT, FATTY ACID AND AMINO ACID PROFILE OF SEA CUCUMBER STICHOPUS NOCTIVAGUS
... Nevertheless, some of them have been over exploited, which may result in a population collapse and also loss of significant potential source of anticancer drug for the future [4]. In spite of the fact that there are many ...
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