FGF-R
FGF receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9
... that FGF-receptor signalling in hindbrain progenitors controls olig2 expression and consequently the generation of both SMNs and OLPs, thereby providing the first evidence for a role of FGF in this ...
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Wnt/β catenin signaling promotes expansion of Isl 1–positive cardiac progenitor cells through regulation of FGF signaling
... on FGF signaling, AHF explants were treated with Wnt3a, SU5402 (a potent FGF receptor inhibitor), or ...of FGF signaling, some of which are positively regulated by both Wnt and FGF signaling ...
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Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos
... adhesion. FGF binds to the receptor tyrosine kinase FGF receptor family (FGFR1- 4), and induces its dimerization and ...2001). FGF functions in the mesoderm and neural induction and their ...
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FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression
... 2013). FGF-2, one of the earliest members identified in the FGF polypeptide family, signals through FGF receptors that have intrinsic tyrosine kinase activity (Powers, Mcleskey, & Wellstein, ...
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Fibroblast surface-associated FGF-2 promotes contact- dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin
... of FGF-2 or FGF receptors (FGFRs) signaling abolishes these ...surface-associated FGF-2, FGF receptor-mediated SRC activation and α v β 5 integrin- dependent cancer cell adhesion to ...The ...
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Fgf signaling instructs position dependent growth rate during zebrafish fin regeneration
... for Fgf signaling during fin regeneration (Poss et ...of Fgf signaling among proximal and distal regenerates might underlie position-dependent blastemal properties and regenerative ...of Fgf ...
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A Screen for Genes That Influence Fibroblast Growth Factor Signal Transduction in Drosophila
... both FGF receptors nases (RTKs) (Karim et ...1991). FGF signal- Biochemical analysis and protein interaction experi- ing is not required for eye development (Casci et ...the FGF receptors via an ...
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FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction
... four FGF receptors at gastrula ...2. FGF signaling is required during gastrulation for proper neural crest ...of FGF signaling during early gastrulation stages (stage 3/3+) causes an inhibition of ...
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Evaluation of the effect of oral taurine supplementation on fasting levels of fibroblast growth factors, β Klotho co receptor, some biochemical indices and body composition in obese women on a weight loss diet: a study protocol for a double blind, randomized controlled trial
... Fibroblast growth factors (FGFs) 19 and 21 as members of FGFs are different from canonical FGFs. FGF19 and FGF21 could circulate in vessels as hormones. They in- crease total energy expenditure. Furthermore, they may ...
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A bi modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain
... requires FGF activity, and loss of FGF activity or Hes1/Hes3 function results in premature differentiation of ventricular zone progenitor cells (Hirata et ...which FGF activity can direct the spatial ...
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A BMP Shh negative feedback loop restricts Shh expression during limb development
... that FGF-MAPK signals oppose BMP-SMAD1 in many developmental organs (De Robertis and Kuroda, ...normal FGF gene transcription in the ...with FGF binding to its receptor, and we show that BMP ...
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Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230
... and grown in AIMC media for 6 days prior to being harvested for RNA. Cells were collected and lysed in HTG Molecular lysis buffer (Tucson, AZ) according the manufacturer’s instructions prior to being shipped to HTG ...
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Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center
... Our experimental approach allowed us to visualize com- prehensive progenitor and neuronal fate maps of Fgf8 + and Fgf17 + RPC progenitors. Importantly, we demon- strated that Fgf8 and Fgf17 mark closely apposed yet ...
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Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants
... Although the secreted molecule Fgf8 is a key player of the isthmic organiser function, the mechanisms by which it acts remain unclear. Here, we present evidence indicating that Fgf8 is not instructive in establishing ...
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Regulation of vascular signalling by nuclear Sprouty2 in fetal lung epithelial cells : implications for co ordinated airway and vascular branching in lung development
... the FGF-10 signal and the duration of this event, a determinant of branch length in the fractal patterning of the airway tree, is antagonised by Spry2 (Tefft et ...that FGF-10 induces direct interac- tion ...
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Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes
... The fossil record indicates that cypriniform fishes, a group including the zebrafish, lost oral teeth over 50 million years ago. Despite subsequent diversification of feeding modes, no cypriniform has regained oral teeth, ...
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Original Article Elevated serum levels of fibroblast growth factor 21 from patients with nephrolithiasis
... ing FGF-21 serum levels among the sick who suffer from type 2 diabetes mellitus while com- paring with healthy people ...together, FGF-21 is likely to be a very important adipo- ...of FGF-21 ...
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FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study
... In this cross-sectional case series, we report for the first time that critically ill patients with AKI due to causes other than rhabdomyolysis have elevated FGF-23 levels compared with critically ill controls. ...
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Acute Sprint Interval Exercise Induces a Greater FGF-21 Response in Comparison to Work-Matched Continuous Exercise
... and FGF-21 analyses, but additional steps for sample preparation should be taken including: 1) pre- chilling EDTA tubes with ice baths before taking blood samples and 2) consistent freezer storage at ...
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In Vitro Effects of the Phytocomplex TrichoTechTM on Human Fibroblasts: Proliferative Potential and Effects on Gene Expression of FGF 7 and FGF 10
... [16] Savio, M., Coppa, T., Bianchi, L., Vannini, V., Maga, G., Forti, L., Cazzalini, O., Lazzè, M.C., Perucca, P., Prosperi, E. and Stivala, L.A. (2009) The Resveratrol Ana- logue 4,4’-Dihydroxy-Trans-Stilbene Inhibits ...
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