foam cells
Original Article Expression of PD-L1 in mononuclear cells, multinucleated cells, and foam cells in tenosynovial giant cell tumors
... ma cells against T-cell-mediated cytotoxicity via upregulating expression of PD-L1, Galectin-9, and HVEM ...multinucleated cells expressing PD-L1 may have important roles in the immune escapes in TGCT ...
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VPO1 mediates oxidation of LDL and formation of foam cells
... and foam cell formation in atherosclerosis remains to be ...monocyte-like cells and promoted formation of foam ...formation foam cells, indicating VPO1 as a novel potential mediator of ...
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Autophagy is associated with cell fate in the process of macrophage-derived foam cells formation and progress
... staged foam cells, with prolonged oxLDL incubation time, autophagosomes continued to increase, and the autophagic flux intensity was gradually enhanced, char- acterized by an increased proportion of LC3II/I ...
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Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells
... A variety of HDL subclasses have been implicated in cellu- lar cholesterol efflux. Small, phospholipid-rich particles, char- acterized as pre b -HDL, have been proposed as the initial ac- ceptors of cholesterol (5), ...
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Control of growth and inflammatory response of macrophages and foam cells with nanotopography
... whereas foam cells displayed an inconsistent pattern of increase of PAI-1 (Figure ...while foam cells demonstrated a significant in- crease at the 50-nm topography (Figure ...the foam ...
9
Lipoprotein lipase is synthesized by macrophage derived foam cells in human coronary atherosclerotic plaques
... atherosclerosis, since it is secreted in vitro by both of the predominant cell types of the atherosclerotic plaque, i.e., macrophages and smooth muscle cells. Because of uncertainty concerning the primary cellular ...
8
Reactive oxygen species produced by macrophage derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro Implications for atherosclerotic plaque stability
... macrophage-derived foam cells were isolated from aortic atheromas and subcutaneous ...and cells were collected in sterile tubes. Foam cells were then isolated by metrizamide density ...
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Macrophage derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low density lipoproteins, and contain oxidation specific lipid protein adducts
... Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of lowdensity lipoproteins, and contain oxidationspeci[r] ...
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Lipoprotein proteoglycan complexes induce continued cholesteryl ester accumulation in foam cells from rabbit atherosclerotic lesions
... macrophage-derived foam cells. Foam cells were isolated from atherosclerotic rabbit ...in foam cells by a dose-dependent, saturable process ...
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7,8 Dihydroneopterin and its effect on the formation of foam cells
... The existence of this signalling pathway is beneficial when considering the other binding site ligands. As well as apoptotic cells the amino acid 155-183 binding site binds Plasmodium falciparum, AGEs and oxLDL ...
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Original Article Clinicopathological characteristics and intrarenal angiotensin II expression in X-linked Alport syndrome
... of foam cell ...and foam cell infiltration were not parallel with obvious glomerular lesions and clinical presen- tation ...epithelial cells [17, ...
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Biological Characteristics of Foam Cell Formation in Smooth Muscle Cells Derived from Bone Marrow Stem Cells
... in cells leads to the formation of foam cells, a pathological feature of atherosclerosis [23, ...vascular cells, can specifically mediate the uptake of ox-LDL ...muscle cells of the ...
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Chymase in exocytosed rat mast cell granules effectively proteolyzes apolipoprotein AI containing lipoproteins, so reducing the cholesterol efflux inducing ability of serum and aortic intimal fluid
... terol from the cells into the medium was measured (Fig. 2 A). With increasing amounts of serum, the rate of cholesterol ef- flux from the foam cells increased rapidly to a steady level at a serum ...
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Original Article Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway
... of foam cells and increase the risk of developing ...of foam cells formation in atherosclerosis. We treated foam cells derived from oxLDL induced THP-1 cells with ...
7
Human apoA-I increases macrophage foam cell derived PLTP activity without affecting the PLTP mass
... macrophage foam cells (MFCs) essential con- stituents of human atherosclerotic lesions ...lesion foam cells and lead to regression of the atherosclerotic process ...
7
<p>Isoborneol Attenuates Low-Density Lipoprotein Accumulation and Foam Cell Formation in Macrophages</p>
... Mono-nuclear cells migrate to the sub-endothelial to be activated and differentiated into macrophages, and macro- phages can phagocytose modi fi ed low-density lipoprotein to form early foam cells ...
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Terminalia Arjuna bark extract impedes foam cell formation and promotes apoptosis in ox-LDL-stimulated macrophages by enhancing UPR-CHOP pathway
... THP1 cells were initially differentiated into macrophages with phorbol-12-myristate-13-acetate (PMA) (100 ng/ml) for 24 h, followed by ox-LDL (100 μ g/ml) treatment for another 24 h to induce foam cell ...
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Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation
... macrophage foam cells are tightly regulated by a complex mechanism that involves internalization of oxidized low-density lipoprotein (oxLDL) and efflux of excess cholesterol ...macrophage foam ...
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Mathematical modelling of the atherosclerotic plaque formation
... This equation reflects the conversion of macrophages into foam cells when they ingest oxydized LDL molecules. The law of mass action is questionable, but we choose it in a first step. We use the product of ...
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Interferon gamma inhibits scavenger receptor expression and foam cell formation in human monocyte derived macrophages
... important mechanism for intracellular cholesterol accumulation in atherosclerosis is supported by the finding of ScR expression in foam cells of atherosclerotic plaques. T lymphocytes are also present in ...
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