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foamy virus

Replacement of feline foamy virus bet by feline immunodeficiency virus vif yields replicative virus with novel vaccine candidate potential

Replacement of feline foamy virus bet by feline immunodeficiency virus vif yields replicative virus with novel vaccine candidate potential

... contain virus spread before adaptive immunity is fully initi‑ ...the virus and host which often provides a barrier against interspecies transmission ...feline foamy virus (FFV) Bet and ...

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Heparan Sulfate Is an Attachment Factor for Foamy Virus Entry

Heparan Sulfate Is an Attachment Factor for Foamy Virus Entry

... a foamy appearance that they induce in adher- ent cell ...simian foamy viruses (SFVs), bovine foamy viruses (BFVs), equine foamy virus (EFV), and feline foamy viruses (FFVs) (34, ...

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Foamy Virus Bet Proteins Function as Novel Inhibitors of the APOBEC3 Family of Innate Antiretroviral Defense Factors

Foamy Virus Bet Proteins Function as Novel Inhibitors of the APOBEC3 Family of Innate Antiretroviral Defense Factors

... simian foamy viruses even though these viruses establish productive infections of a wide range of primate species, including chim- panzees, and are in fact common in both captive and wild simians (16, 33, ...

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Carrier Cultures of Simian Foamy Virus

Carrier Cultures of Simian Foamy Virus

... Effect of foamy virus neutralizing antiserum on the percentage of positive cells in carrier cultures which contained detectable virus antigen Carrier-cell type' Time weeks 3 4 9 HEp-2 BH[r] ...

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Isolation and Characterization of an Equine Foamy Virus

Isolation and Characterization of an Equine Foamy Virus

... Immunological reactivity of horse sera against HFV anti- gens. While several distinct primate FV isolates have been characterized, reflecting their widespread distribution among primate species, only BFV and the recently ...

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Insights into the structure and activity of prototype foamy virus RNase H

Insights into the structure and activity of prototype foamy virus RNase H

... Background: RNase H is an endonuclease that hydrolyzes the RNA strand in RNA/DNA hybrids. Retroviral reverse transcriptases harbor a C-terminal RNase H domain whose activity is essential for viral replication. The RNase ...

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Foamy virus zoonotic infections

Foamy virus zoonotic infections

... bovine foamy virus (BFV) transmis- sion in herds of cattle ...and virus from their mothers, but did not produce significant amounts of virus before ...from virus spread by maternal ...

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Further Characterization of Equine Foamy Virus Reveals Unusual Features among the Foamy Viruses

Further Characterization of Equine Foamy Virus Reveals Unusual Features among the Foamy Viruses

... nonprimate FVs have been isolated to date: the bovine foamy virus (BFV), the feline foamy virus (FFV), and the equine foamy virus (EFV). This latter was recently isolated from ...

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Tetherin inhibits prototypic foamy virus release

Tetherin inhibits prototypic foamy virus release

... simian foamy virus (SFV) and feline foamy virus (FFV), and this restriction was counteracted by the Bet protein ...paramyxoviral virus-like particles (VLPs) ...sarcoma virus ...

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Basic Residues in the Foamy Virus Gag Protein

Basic Residues in the Foamy Virus Gag Protein

... Foamy virus (FV) capsid proteins have few ...(wt) virus and were genetically stable in gag upon 10 cell-free ...generate virus-like particles (VLPs) or to undergo pseudotyping by a ...

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Evidence that the Human Foamy Virus Genome Is DNA

Evidence that the Human Foamy Virus Genome Is DNA

... Human foamy virus (HFV) is the prototype virus of the Spumavirus genus of ...human virus because the first isolation was from a human cancer-derived cell line (1); however, recent analyses ...

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Foamy Virus Particle Formation

Foamy Virus Particle Formation

... human foamy virus (HFV) structural gag, gag/pol, and env genes were constructed and used to analyze foamy virus particle formation by electron ...

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Active foamy virus proteinase is essential for virus infectivity but not for formation of a Pol polyprotein.

Active foamy virus proteinase is essential for virus infectivity but not for formation of a Pol polyprotein.

... of virus particles harvested after transient transfection of BHK21 or BHK FAB cells (34) with plasmids pHSRV13, pHSRV-D/A, and pHSRV-S/T, respectively (Table ...infectious virus particles were recovered in ...

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Persistent Infection with Primate Foamy Virus Type 1 Increases Human Immunodeficiency Virus Type 1 Cell Binding via a Bet-Independent Mechanism

Persistent Infection with Primate Foamy Virus Type 1 Increases Human Immunodeficiency Virus Type 1 Cell Binding via a Bet-Independent Mechanism

... the virus cycle in dually infected ...leukemia virus types 1 and 2) (31), human herpesviruses (human herpesvirus type 6 [HHV-6], HHV-7, and HHV-8) (4, 7, 9, 12, 32), or nonpathogenic flavivirus GB ...

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Relationship of the env genes and the endonuclease domain of the pol genes of simian foamy virus type 1 and human foamy virus.

Relationship of the env genes and the endonuclease domain of the pol genes of simian foamy virus type 1 and human foamy virus.

... Relatedness of human foamy virus and simian foamy virus type 1 Amino acid sequences Conserved Similar % Similarity' pol gene endonuclease External Transmembrane env domain env domain 73 [r] ...

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Foamy virus vectors.

Foamy virus vectors.

... HFV has been cloned as an infectious provirus (22, 39), and a recent report describes the construction of replicating foamy virus vectors with deletions in the bel2-3 region (45). We have constructed ...

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Nonintegrating Foamy Virus Vectors

Nonintegrating Foamy Virus Vectors

... nonintegrating foamy virus (NIFV) vectors by introducing point mutations into the highly conserved DD35E catalytic core motif of the foamy virus integrase ...

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The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding

The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding

... coli: Escherichia coli; FV: Foamy virus; GB1: Immunoglobulin binding domain B1 of streptococcal protein G; HIV-1: Human immunodeficiency virus type 1; PFV: Prototype foamy virus; MoMLV: [r] ...

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Molecular Characterization of Proteolytic Processing of the Pol Proteins of Human Foamy Virus Reveals Novel Features of the Viral Protease

Molecular Characterization of Proteolytic Processing of the Pol Proteins of Human Foamy Virus Reveals Novel Features of the Viral Protease

... Human foamy virus (HFV) is the prototypic spumavirus that has distinct features of gene expression different from those of other known ...retroviruses. Foamy viruses (FVs) as complex retroviruses ...

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Subviral Particle Release Determinants of Prototype Foamy Virus

Subviral Particle Release Determinants of Prototype Foamy Virus

... 1D, SVP release analysis normalized for cellular expression levels revealed the following: i partial or complete deletion of the CyD of the TM subunit ⌬C981 and ⌬C975 in the wild-type ba[r] ...

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