fold change
Appendix A Table S1: Genes whose >1.5x absolute fold-change did not meet the individual CUT
... Figure S2: Presence of non-touching precursor oligodendrocytes regulates the Circadian Rhythm (CR) pathway. (a) Regulation of the interconnected genes within CC pathway. (b) Expression ratios and individual ...
12
Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments
... distributional fold change (DFC) test, which is based on the analysis of the distribution of intensities of all fea- tures on a microarray mapped to a three dimensional feature space composed of the average ...
16
Multilaboratory Assessment of Threshold versus Fold-Change Algorithms for Minimizing Analytical Variability in Multiplexed Pneumococcal IgG Measurements
... Multiplex immunoassays are some of the most analytically com- plex techniques in clinical use. As such, they can be prone to sub- stantial analytical variability between laboratories, particularly for LDTs that are ...
7
Moderated estimation of fold change and dispersion for RNA seq data with DESeq2
... of fold change estimates We benchmarked the DESeq2 approach of using an empirical prior to achieve shrinkage of LFC estimates against two compet- ing approaches: the GFOLD method, which can analyze ...
21
Original Article Global gene expression profile of schizosaccharomyces pombe cells to sodium fluoride
... and fold change were used to pick out significant genes among the differ- ent groups, with the False Discovery Rate (FDR) set less than ...and fold change greater than ...
15
EVALUATION OF MICRORNA 21 IN INVASIVE DUCTAL CARCINOMA IN COMPARISON TO CLINICOPATHOLOGICAL STATUS BY STEM LOOP RT PCR PROCEDURE
... Background:- MiR-21 was one of the first oncogenic miRs and as an anti-apoptotic factor, to be characterized, being up-regulated in numerous tumors including BC . A novel miR quantification method has been established ...
11
Age and sex differences in kidney microRNA expression during the life span of F344 rats
... highest fold-change differences between sexes (miR-208*, with 21-fold change F > M) and most pro- longed, sex-biased expression (miR-421*, at 15, 21, 78, and 104 ...
16
GLUT4 expression and glucose transport in human induced pluripotent stem cell-derived cardiomyocytes
... Fold change GLUT4 Maturation Medium Condition 1 0 mM glucose 1x ITS supplement 860 nM insulin 3.6 fold increase 1.4 fold increase Maturation Medium Condition 2 5.5 mM glucose 1 x ITS sup[r] ...
16
Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities
... We then performed time-lapse imaging on CaP arbors over a period of 3 h, a benchmark lifetime for putative synapse stabilization [67] (Fig. 3c) in order to assess if Dynactin1a depletion led to instability at 2dpf which ...
22
Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation
... the physical interactions annotated in the BioGrid database for S. cerevisiae (release 2.0.49) were formatted into an Excel spreadsheet and then uploaded into Cytoscape using the function “Import Network from a table”. ...
15
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response
... The expression of circulating mature miRNAs in rat plasma was analysed with Rat miRBase Profiler HC (Plates 1 and 2) miScript™ miRNA PCR Array, following the manufacturer’s protocol. Briefly, total plasma RNA was used to ...
16
The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis insights for early bactericidal activity?
... Whole genome gene expression analyses were per- formed. Microarray experiments were performed using a custom Agilent tiling array with 180,000 60-mer oligos evenly tiled across the M. tuberculosis H37Rv genome. Features ...
11
The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription
... The ce10/WS220 genome fasta file was obtained from the WormBase ftp server. Sequences for the piRNA sensor transgene and the piRNA sensor transgene with one intron were added as separate chromosomes when required. A GTF ...
22
Effect of sample size and P value filtering techniques on the detection of transcriptional changes induced in rat neuroblastoma (NG108) cells by mefloquine
... The fold-change and P-value filtering methods were com- pared in terms of their ability to detect (not detect) genes differentially modulated by mefloquine (Table ...The fold-change and P < ...
11
A fingerprint pair analysis of hERG inhibition data
... After computing all the transformations in the data, we group the pairs such that those making the same chemical transformation are aggregated together. Each aggregate is summarized by its mean hERG inhibition and the ...
8
Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjects
... drug concentration in plasma; CV, coefficient of variation; FC, fold change; % Δ lDl-c, percentage change in low-density lipoprotein cholesterol from baseline to 48 hours after atorvast[r] ...
12
Validation of Plasmodium falciparum dUTPase as the target of 5′ tritylated deoxyuridine analogues with anti malarial activity
... the fold change in IC50 of the different compounds tested, the action of compounds 3 and 4 was clearly dependent on enzyme ...eight- fold less active against the enzyme than compound 3 although both ...
12
Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity
... relative fold- change from hyperoxia to physioxia (Additional file 2: Figure S2), high-GAG MSCs upregulated a majority (80 %) of oxygen-responsive genes, including those of the HIF regulatory and TGF-β ...
12
Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation.
... between poor prognosis and good prognosis samples of GIIIA or GBM (Fig. 2a-b). Only microRNAs that are significantly differentially expressed between each stage of the OP differentiation pathway and with at least a ...
11
Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat
... Fig 8. RNA-sequencing reveals the role of FGRRES_16221 in coordinating fungal metabolism and virulence factors to promote infection without activating inhibitory wheat defences. Wheat tissues sampled for RNA-sequencing ...
27