gene specific co-regulation
Discover gene specific local co-regulations using progressive genetic algorithm
... of gene specific co-regulation discovery is that, for a particular gene of interest, identify its closely co- regulated genes and the associated subsets of experimen- tal ...
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Regulation of Dictyostelium prestalk specific gene expression by a SHAQKY family MYB transcription factor
... fusion gene containing the MybE-coding region; linked at its C terminus to GFP and under the control of a semi-constitutive actin ...a co-transformation with the ecmAO:lacZ ...ecmAO:lacZ gene ...
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Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis
... highly co-expressed and interconnected with MAPT and/or GRN (Additional file 2: Table S1a and ...were co-expressed with MAPT and GRN, respectively, in frontal cortex and/or temporal cortex, but also that ...
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Genetic regulation of sex-specific gene expression in mouse liver
... liver gene expression using more than one strains of mice and reported a list of sexually dimorphic genes at comparable threshold ...and co-workers (49) reported that about 17% genes are sexually dimorphic ...
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Regulation of the mouse alfaB crystallin and MKBP/HspB2 promoter activities by shared and gene specific intergenic elements: the importance of context dependency
... In vivo interactions of Sp1 and GR with the intergenic region Mutations in the Sp1 binding element α BE3 selectively lowered α B-crystallin promoter activity (Fig. 2). However, co-transfection experiments ...
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Synergistic regulation of cdc2 and cyclin A gene transcription by co-operating oncogenes
... and co-transfected with pE lA (12S E lA ), ...3). Co-transfection of ras (compare lanes 1 and 2) does not affect the levels of the lacZ protected signal, implying that expression of control lacZ mRNA is not ...
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Alternative splicing: an important mechanism for myometrial gene regulation that can be manipulated to target specific genes associated with preterm labour
... (A) Co-localisation of the antagonistic splicing factors SF2/ASF and hnRNPA1 within the nuclei of human myometrial cells by fluorescence confocal microscopy; Nuclei (blue) were defined by staining with ...DNA; ...
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Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
... our gene network analysis identified a cluster of 18 upregulated lncRNAs co-expressed with protein-coding genes involved in cell cycle ...upregulated gene in colorectal cancers and gliomas, ...
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Control of neurone-specific gene expression: Transcriptional regulation of the M1 muscarinic acetylcholine receptor gene
... conditions. Again, this is the case for Y Y l (review ed in (Shi et a l , 1997; Thomas and Seto, 1999)), which as a default mode acts as a repressor, but under certain situations, such as in the presence o f E lA , an ...
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The Diaphanous-Related Formins : Dynamic Regulators of Smooth Muscle Cell-Specific Gene Transcription
... S1070 to alanine or addition of the Rho-kinase inhibitor, Y-27632, completely eliminated this phosphorylation. The upper band visible in these blots represents Rho-kinase auto- phosphorylation and serves as an excellent ...
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Specific growth rate governs AOX1 gene expression, affecting the production kinetics of Pichia pastoris (Komagataella phaffii) PAOX1-driven recombinant producer strains with different target gene dosage
... the regulation of their expression in presence of methanol must be coupled ...CRL1 gene dosage in fed‑batch (FB) cultivations. a Specific methanol consumption rate (q s ), overall ...
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Metabolic regulation of Escherichia coli cultivated under anaerobic and aerobic conditions in response to the specific pathway gene knockouts
... a co-ordinated ...This regulation pattern clearly demonstrates that the ppc mutant utilizes an al- ternative anaplerotic pathway, the glyoxylate shunt, to replenish OAA in response to the blockage through ...
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In silico analysis of the grapefruit sRNAome, transcriptome and gene regulation in response to CTV CDVd co infection
... often co-infected with CTV and viroids prompted a recent study which investigated the co-infection of CTV and CDVd in their respective indicator plants, Mexican lime and etrog citron ...the ...
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Regulation of cell type-specific gene expression in melanocytes and melanoma
... To ask whether the melanoma-specific octamer-binding protein detected in the melanoma cell extracts was in any way reiated to Brn-2 as suggested by the comparative band shift assays, nuciear extracts from SKfJel28 ...
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Tissue specific regulation of CYP2B gene expression
... CYP2B2 gene expression in transfected rat hepatoma cells (Shaw et ...to co-transfect a CYP2B1 or CYP2B2 promoter-reporter construct together with a plasmid expressing HNF-4 protein and to examine the ...
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Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system
... XRDH10 gene expression, suggesting negative- feedback ...the gene expression of organizer markers, and synergized with XRALDH2 in posteriorizing the developing ...by specific antisense morpholino ...
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Tissue and development specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase
... nNOS gene (3), using Superscript II RNase H- Reverse Transcriptase (GIBCO BRL Life Technologies, ...the gene-specific primers N2 (5 9 -tgtccccgcccccttccttactct-3 9 ) or N3 (5 9 - ...
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A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2.
... To determine whether negative regulation of the MIEP is HCMV specific, the MIEP of human, simian, or murine CMV upstream of the CAT gene was cotransfected with either control plasmid pLi[r] ...
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Skeletal muscle gene expression in response to resistance exercise: sex specific regulation
... of gene transcriptional ...on gene expression such as the influence of different genetic backgrounds, neuro- hormonal states, and other physiological and environ- mental factors that may exist among ...
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Setd5 is essential for mammalian development and the co transcriptional regulation of histone acetylation
... regulating gene expression during development through modifications in chromatin ...PAF1 co-transcriptional complex and other ...perturbed gene expression. SETD5 co-immunoprecipitates with ...
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