genome-wide association
Q&A: Promise and pitfalls of genome-wide association studies
... The odds ratio is simply the probability of having the disease given one genotype at a SNP (or other genetic variant) divided by the probability of having the disease given another genotype at the SNP. In a statistical ...
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Semantically enabling a genome-wide association study database
... “Genome-wide association study identifies eight loci associated with blood pressure” ...“Genome-wide association study of acute post-surgical pain in humans” ...
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Progress of genome wide association study in domestic animals
... the genome-wide level can be traced back to the ...the genome- wide ...The genome wide association study (GWAS) is a new technique for the identification of causal genes ...
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GENOME-WIDE ASSOCIATION STUDIES IN PHARMACOGENOMICS
... The aim of this study is to review the applications of genome-wide association studies (GWAS) in pharmacogenomics. GWAS have matured into a powerful tool to identify single nucleotide polymorphisms ...
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Genome wide association study for multiple phenotype analysis
... The increasing availability of high-density genomic data with thousands of samples enables the identification of single-nucleotide polymorphisms (SNPs) contributing to complex traits on a genome-wide scale. ...
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Genome-Wide Association Studies in Glioma.
... 2009, genome-wide association studies (GWAS) have been successful in identifying germline variants associated with glioma ...assessing association of germline risk SNPs with particular ...
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SNP2GO: Functional Analysis of Genome-Wide Association Studies
... ABSTRACT Genome-wide association studies (GWAS) are designed to identify the portion of single-nucleotide polymorphisms (SNPs) in genome sequences associated with a complex ...
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Genome wide association studies: a primer
... Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, Libioulle C, ...
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Regularized regression method for genome wide association studies
... Genome-wide association studies (GWAS) are a modern approach to genetic ...delineating association sig- nals by achieving smoothness and reducing randomness in single-SNP ...
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Meta analysis of genome wide association studies.pdf
... Genotyping and imputation. Subjects for the stage 1 and 2 analyses were genotyped with high-density SNP typing platforms that covered the entire human genome. In most of the studies, only unrelated samples with ...
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Enrichment of statistical power for genome-wide association studies
... Genome-wide association studies (GWAS) are widely used in human genetics research to identify genes asso- ciated with complex diseases and in agricultural research to identify genes associated with ...
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On Considering Epistasis in genome Wide Association Studies.
... Brinza,D., Schultz,M., Tesler,G., and Bafna,V. (2010). RAPID Detection of gene–gene Interactions in Genome-Wide Association Studies. Bioinformatics 26 (22) 2856-2862. Burton,P. R., Clayton,D. G., ...
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Genome-wide association analysis identifies a meningioma risk locus at 11p15.5.
... a genome-wide association study, which identified a risk locus at chromosome ...two genome-wide association studies and two independent validation series comprising 2,138 cases ...
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Genome wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome wide linkage results
... GWAS: Genome-wide association studies; HDL: High-density lipoprotein; IBD: Identical by descent; LD: Linkage disequilibrium; LDL: Low-density lipoprotein; NARAC: North American Rheumatoid Arthritis ...
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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
... the genome-wide complex trait analysis procedure (GCTA), genome-wide association studies (GWAS) found that ~ 51% (the ...no genome-wide signi fi cant single SNP ...detect ...
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Genetics of migraine in the age of genome-wide association studies
... genetic association studies of variants in genes involved in dopamine metabolism ...the genome for associations with the migraine phenotype or certain migraine ...and genome-wide ...
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Genome-wide association studies with metabolomics
... Genome-wide association studies (GWAS) analyze the genetic component of a phenotype or the etiology of a disease. Despite the success of many GWAS, little progress has been made in uncovering the ...
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Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes.
... a genome-wide association analysis for a set of sampled and imputed SNPs with 16 conformation traits in a population of Mexican Holstein cows, revealed eight significant SNPs: one associated with the ...
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Genome-wide association studies of cancer: current insights and future perspectives.
... from association studies, in particular genome-wide association studies (GWAS), both in terms of understanding the allelic architecture of cancer susceptibility and its functional basis as ...
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A genome-wide association study in multiple system atrophy
... Research Council UK, Well- come Trust, and the Reta Lila Weston Institute for Neurological Studies. B. Traynor was supported in part by the Intramural Research Program of the National Institutes of Health (National ...
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