germ cell specification
Dynamic redistribution of vasa homolog and exclusion of somatic cell determinants during germ cell specification in Ciona intestinalis
... somatic cell differentiation during the cleavage stages, can be detected in the presumed ...somatic cell development may have additional roles in germ cell ...regulate germ cell ...
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Mechanisms of germ cell specification across the metazoans: epigenesis and preformation
... before germ layer separation; after germ layer separation but before gonadogenesis; or after gonadogenesis and continuously throughout adult ...of germ cells with those based on molecular techniques ...
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The Dr nanos gene is essential for germ cell specification in the planarian Dugesia ryukyuensis
... stem cell (GSC) systems and for gametogenesis in many ...of germ cells in the ovaries and testes and may have a function in the early stages of germ cell specification, but not in the ...
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A polymorphic, thrombospondin domain containing lectin is an oocyte marker in Hydractinia: implications for germ cell specification and sex determination
... ABSTRACT We have identified a novel, multidomain, polymorphic lectin in the marine cnidarian Hydractinia echinata. The gene is expressed in oocytes and was therefore named CEL for cnidarian egg lectin. The predicted ...
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Nodal induces sequential restriction of germ cell factors during primordial germ cell specification
... precursor germ cells have low transcriptional activity (Seydoux and Dunn, 1997; Swartz et ...urchin germ cell precursors, for example, have marked quiescence that includes nearly undetectable ...
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Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells
... thereafter, thousands of pre-induced cells were cultured under a floating condition in the presence of similar sig- naling molecules (BMP2 or BMP4, SCF, EGF, and LIF) to form embryoid bodies. After 6–8 days, hPGCLCs ...
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Germ cell specification and ovary structure in the rotifer Brachionus plicatilis
... of cell types by light ...conserved germ cell markers during embryo- ...specific cell types within the oocyte throughout embryonic development - despite the the ubiquitous mRNA distribution of ...
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DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
... Drosophila germ plasm, and are highly conserved in germ cell ...determined germ line inherit these gene products as maternal factors, Dazl and Mvh are expressed in postmigratory germ ...
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Delayed male germ cell sex specification permits transition into embryonal carcinoma cells with features of primed pluripotency
... embryonic germ cells harbor features of naïve pluripotency prior to sex-specific differentiation, they lack one characteristic of this cell type, ...inner cell mass of blastocysts (Le Bin et ...
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The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse
... for specification of the mammalian germ ...during germ-cell ...both germ cell and posterior mesoderm/allantoic fates in a dose-dependent ...during germ-cell ...
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Developmental fates of the mouse germ cell line
... programmed cell death, and degeneration of type A2-A4 spermatogonia has been observed in ...spermatocytes, germ cell apoptosis detected by the terminal deoxynucleotide transferase-mediated ...
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Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin
... of germ line specification in this phylum are not known, their eggs do not have obvious preformed germ line components (Ransick et ...its germ line is considered to be conditionally specified ...
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EFFECTIVENESS OF CHEMOTHERAPY AMONG CHILDREN WITH SOLID TUMORS: A STUDY
... nerve cells. Astrocytomas are brain tumors that shape in astrocyte cells, which are an explicit kind of glial cell. About portion of brain tumors in children are astrocytomas. As most gliomas start from ...
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Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors
... ES cell and germ cell marker Stella, presumably due to their epigenetic ...ES cell maintenance only requires the cytokine LIF, a member of interleukin-6 family that signals via the gp130 ...
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Primordial germ cell migration
... 2003), cell-cell adhesion (E-cadherin and foi) (Bendel-Stenzel et ...mouse, germ cell adhesion may be controlled via a PGC intrinsic clock as PGCs in culture cluster and become non-motile at ...
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Application of the International Germ Cell Consensus Classification to the Nova Scotia population of patients with germ cell tumours
... app murphy la CUAJ ? April 2009 ? Volume 3, Issue 2 ? 2009 Canadian Urological Association 120 ORIGINAL RESEARCH Application of the International Germ Cell Consensus Classification to the Nova Scotia[.] ...
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fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans.
... can continue to make sperm even in the presence of only one functional copy of fog-I. There- fore, the fog-1 defects associated with mutations that were isolated by s[r] ...
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In vitro anticancer activity of wheat germ extract on human breast cancer cell line (MCF-7) and human immortalized myelogenous leukemia cell line (K562)
... leukemia cell line was obtained from (Faculty of Medicine, The University of Jordan) and was cultured in RPMI while the MCF-7 breast cancer cells were obtained from American Type culture collections (ATCC) and ...
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Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling
... To identify specific Coco-regulated TGFβ ligands, CocoMO injections were coupled with injection of MOs targeting specific TGFβ ligands (ActivinMO or Xnr5/6MO + β-Gal tracer) in order to test whether we could inhibit this ...
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Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non- coding RNAs
... In order to manipulate Wnt signalling more precisely without the influence of paracrine signals that are operational in vivo, we utilized a well-studied in vitro model of spermatogonial cells (GC1 cells, [32]) to ...
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