Germ layer
Lin28 proteins are required for germ layer specification in Xenopus
... regulate germ layer specification, and that this early function is probably independent of the recognised role of Lin28 proteins in negatively regulating let-7 miRNA ...
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Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo
... into germ layers during gastrulation; however, the cellular and molecular details are not well defined due to intrauterine ...of germ-layer formation, using immunohistochemistry and time-lapse ...
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The zebrafish tailbud contains two independent populations of midline progenitor cells that maintain long term germ layer plasticity and differentiate in response to local signaling cues
... different germ layer derivatives form from a single pool of MPCs, whereas in mouse embryos the notochord and floor plate progenitors are spatially distinct (Catala et ...post-gastrula germ ...
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A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions
... Methods: Human peripheral blood buffy coat cells and mobilized CD34 + cells from human blood and from blood from C57Bl/6 J mice were cultured in hybridoma medium or neural stem cell induction medium supplemented with ...
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A thrombomodulin-like gene is crucial to the collective migration of epibolic blastomeres during germ layer formation and organogenesis in zebrafish
... enveloping layer (EVL) retains the external yolk syncytial nuclear (YSN) within the margin of ...ial layer and extending from animal pole to vegetal pole in yolk cytoplasmic layer ...with germ ...
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The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation
... In a direct screen for secreted proteins in early Xenopus embryos, we identified Protease nexin-1 (PN1) (Pera et al., 2005). PN1, which is also known as Glial-derived nexin or SerpinE2, is a serine protease inhibitor ...
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Klf4 is required for germ layer differentiation and body axis patterning during Xenopus embryogenesis
... In congruence with the phenotypes above, injection of Klf4 or dnXAR1 RNA alone resulted in ectopic expression of XAG2, an anterior marker gene. When they were injected together, much stronger XAG2 expression was observed ...
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Mechanical cell properties in germ layer progenitor migration during zebrafish gastrulation
... Various hypotheses explain cell sorting and tissue organization on the basis of the adhesive and mechanical properties of the constituent cells (Tepass et al., 2002) (Fig.1.17). One of the most prevalent hypotheses, the ...
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Regulation of germ layer formation by pluripotency factors during embryogenesis
... ectodermal cells to BMP signaling, thus playing a role in the fate choice of ectoderm. Studies by Cao et al. [36] and by Snir et al. [41] have demonstrated that Xenopus POU-V factors promotes neuroectoderm formation but ...
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SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)
... Fig. 1. Identification of TFs that efficiently differentiate ESCs into three germ layers by analyzing the NIA mouse ESC bank. (A) Schematic diagram of TF- inducible ESCs: each ESC line in the NIA mouse ESC bank ...
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Spiralian gastrulation: germ layer formation, morphogenesis, and fate of the blastopore in the slipper snail Crepidula fornicata
... Some might view the behavior of cells at the posterior blastopore lip in Crepidula as an example of the pro- posed transition from amphistomy to protostomy (see [3, 5]), At the beginning[r] ...
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How to make a primordial germ cell
... mouse germ cell biology, which will provide the basis for studies on germ cells of other mammalian species, including ...the germ cell genes and in the initiation of epigenetic modifications in early ...
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The early development of germ cells in chicken
... Among aves, the long-term culture system of chicken PGC has been successfully established (van de Lavoir et al., 2006). It has been shown that bFGF plays an essential role in the proliferation and survival of chicken ...
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Neuroimaging of disseminated germ cell neoplasms
... Involvement of a solitary vertebral level was not TABLE 1: Neuroimaging Findings in Patients with Germ Cell Neoplasms Finding CNS metastases Intracranial Supratentorial lnfratentorial Bo[r] ...
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On the number of founding germ cells in humans
... the germ cell population ...the germ-cell development in human females, we show that the large variance observed in counts of human oocytes is consistent with the initial origin of these cells from a much ...
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Poised chromatin in the mammalian germ line
... mammalian germ line at the promoters of genes required for differentiation of all somatic lineages across multiple stages of germ cell ...the germ line is to regulate somatic developmental gene ...
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Germ line polysomy in Atractomorpha similis
... 168 individuals of this species contain a large number of heterochromatic segments on their standard chromosomes, while others carry a large amount of heterochromatin as B chromosomes, a[r] ...
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Application of the International Germ Cell Consensus Classification to the Nova Scotia population of patients with germ cell tumours
... (International Germ Cell Consensus Classifica- tion) est un système de classification pronostique mondialement reconnu, basé sur les données cliniques et utilisé pour faciliter la prise en charge des tumeurs ...
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Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors
... gonadal germ cells, which, instead of differentiating into spermatogonia, develop as pre-invasive CIS (Skakkebaek ...fetal germ cells and pluripotency ...by germ cell-like gene expression and are the ...
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Imaging of testicular germ cell tumours.
... Testicular germ cell tumours (GCT) are an increasingly common group of tumours, particularly in young males. The success of current management strategies is such that the majority of patients can expect to be ...
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