Germline Stem Cells
Ovarian germline stem cells
... Germline stem cells (GSCs) are a unique cell population committed to producing gametes for the propagation of the ...self-renewing cells must be present in the testis which could produce ...
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Germline stem cells and sex determination in Hydra
... of germline stem cells (GSCs) in Hydra is determined in a cell-autonomous ...sperm-restricted stem cells (SpSCs), while females have egg-restricted stem cells ...
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Mei P26 regulates the maintenance of ovarian germline stem cells by promoting BMP signaling
... maintain germline stem cells (GSCs) in an undifferentiated ...promoting germline cyst development. Within undifferentiated germ cells, Mei-P26 associates with miRNA pathway components ...
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Previously claimed male germline stem cells from porcine testis are actually progenitor Leydig cells
... Male germline stem cells (mGSCs), localized to the basal lamina of seminiferous tubules, are a special kind of adult stem cell because they have the capacity to main- tain self-renewal and to ...
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Effete mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila
... It has been shown that APC/C activity is required for the asymmetric localization of Miranda and its cargo proteins during neuroblast division (Slack et al., 2007). In Drosophila ovary, previous studies have demonstrated ...
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Ovarian Germline Stem Cells in the Teleost Fish, Medaka (Oryzias latipes)
... We study the mechanism underlying the for- mation of ovary and testes using teleost fish, medaka (Oryzias latipes) as a model. Medaka spawns several dozens of eggs every day for about one year in artifi- cial ...
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Rab11 maintains connections between germline stem cells and niche cells in the Drosophila ovary
... All stem cells have the ability to balance their production of self-renewing and differentiating daughter ...The germline stem cells (GSCs) of the Drosophila ovary maintain such balance ...
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The Posterior Determinant Gene nanos Is Required for the Maintenance of the Adult Germline Stem Cells During Drosophila Oogenesis
... multipotential stem cells are responsible for maintaining a germinal population and generating a differentiated ...Drosophila germline is one such tissue where a continuous supply of eggs or sperm ...
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Male germline stem cells in non-human primates
... mammalian germline stem cells ...human germline development and ...vitro germline stem cell terminology from primordial to differentiating germ ...germ cells (PGCs) are ...
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The glypican Dally is required in the niche for the maintenance of germline stem cells and short range BMP signaling in the Drosophila ovary
... GSC-like cells accumulate Fig. 2. dally is required in the somatic niche cells for ovarian GSC ...a germline-specific marker; Spectrin, a fusome component used to distinguish GSC and the ...
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Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad
... Pole cells were isolated from donor embryos at the cellular blastoderm stage and injected into the posterior pole of same stage host ...pole cells (average 2.2 pole cells) from a single embryo were ...
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PAX7 expression defines germline stem cells in the adult testis
... testis stem cell ...a stem cell in the assay. However, other investigators in the stem cell field have challenged the assumption that transplan- tation assays recapitulate stem cell function ...
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Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis
... red cells) and somatic stem cells (also known as cyst progenitor cells; red elliptical cells) directly contact the hub cells (gray ...cyst cells, moves away from the hub ...
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An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivo
... matogenic cells when lentiviral vector-mediated cells were xeno-transplanted into the seminiferous tubules of immunodeficient mice, and microinsemination of these transgenic germ cells resulted in ...
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Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure
... germ cells and the surrounding somatic cells, however, chemother- apy could destruct the ovarian niches, decrease granu- losa cell function and induce ovarian toxicity ...transplanted stem ...
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Without children is required for Stat mediated zfh1 transcription and for germline stem cell differentiation
... cap cells (CC) are at the anterior (left). Germline stem cells (GSCs) and their daughters (cystoblasts, CBs) carry spherical fusomes ...(yellow). Germline cysts contain branched fusomes ...
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The control of sexual identity in the Drosophila germline
... discuss germline sexual identity within the context of the different stages of germline sexual development and the decisions that germ cells face along the way (see Box 1 for a discussion of ...of ...
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Rapid population wide declines in stem cell number and activity during reproductive aging in C elegans
... the germline declines early in adult life, we applied state-of-the-art techniques to characterize the cellular and molecular changes that underlie age-related functional decline using sperm- replete animals before ...
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The centrosome orientation checkpoint is germline stem cell specific and operates prior to the spindle assembly checkpoint in Drosophila testis
... male germline stem cells (GSCs) possess a checkpoint mechanism that coordinates cell polarity and cell division (Cheng et ...hub cells, which constitute the major component of the stem ...
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Reinterpretation of evidence advanced for neo- oogenesis in mammals, in terms of a finite oocyte reserve
... germ cells, in the light of data presented [7,10], countermands the existence of neo-oogenesis and female germline stem ...of germline stem cells in the ovary [7,12,15]; but ...
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