Growth differentiation factor (GDF9)
Growth differentiation factor 15 contributes to marrow adipocyte remodeling in response to the growth of leukemic cells
... Growth differentiation factor-15 (GDF15), a TGF- β / bone morphogenetic protein (BMP) superfamily mem- ber, is a 40-kDa secretory propeptide that is cleaved in the endoplasmic reticulum to release a ...
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Growth differentiation factor 6 and transforming growth factor beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs
... Growth differentiation factor 5 (GDF5/BMP-14/CDMP- 1) and growth differentiation factor 6 (GDF6/BMP-13/ CDMP-2) are members of the TGF superfamily and are as- sociated with ...
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Quantitative analysis of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) gene expression in calf and adult bovine ovaries
... BMP15, GDF9, and GAPDH cDNAs to quantify the amplified ..., GDF9: 5 ’ - AGCGCCCTCACT GCTTCTATAT-3 ’ and 5 ’ - TTCCTTTTAGGGTG- GAGGGAA-3 ’ , FSHR: 5 ’ -AATCTACCTGCTGCTCA- TAGCCTC-3 ’ and 5 ’ - ...
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Growth differentiation factor 9 and bone morphogenetic protein 15 expression in previtellogenic oocytes and during early embryonic development of Yellow-tail Kingfish Seriola lalandi
... transforming growth factor β super family (TGF-β), GDF9 and BMP15 ...These growth factors stimulate the proliferation of granu- lose cells, but also suppress follicle stimulating hormone ...
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Investigation of polymorphic variation in the growth differentiation factor-9 gene (GDF9) in New Zealand sheep breeds
... sheep GDF9 protein sequence against the mouse, human, cow and dog is given in ...that GDF9 sequences are most similar between mammals that have a similar ...
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The Effect of Growth Differentiation Factor-5, 6, 7 in Chondrogenic Cell Differentiation of ATDC-5
... chondrogenic differentiation marker genes (Sox9, Collagen Type II (Col2), Collagen Type X (ColX), and Aggrecan) were analyzed using real-time quantitative RT-PCR (MX3005P, Agilent Technologies, Tokyo, Japan); ...
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The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review
... a growth factor signalling cascade that highly regulates the proliferation and differentiation of ovarian cells (Figure 1), (Nagashima et ...important growth factors include genes of the TGFB ...
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Identification of mutations in BMP15 and GDF9 genes associated with prolificacy of Markhoz goats
... The growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are attractive candidates expressed by the oocyte and are associated with increased ovulation rate in ...in ...
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Genetic analysis of female infertility with the effect of human bmp15 and gdf9 genes: a review
... the gdf9 and bmp15 genes and diseases such as premature ovarian failure (POF) and polycystic ovary syndrome (POS) had occurred (Laissure et ...and growth differentiation factor 9 (GDF9) ...
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Serum Growth Differentiation Factor 15 in Patients with Ulcerative Colitis
... Increased cytokine levels during inflammation are said to play a major role in the pathogenesis of ACD at various levels. It affects EPO production, erythroid response to EPO, life span of red blood cells and iron ...
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BMP15 and GDF9 Gene Mutations in Premature Ovarian Failure
... Ovarian function is regulated by a combined stimulus of gonadotropins, follicular stimulating hormone (FSH), luteinizing hormone, and local ovarian factors such as inhibins, activins, bone morphogenetic protein 15 ...
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Diclofenac and triamcinolone acetonide impair tenocytic differentiation and promote adipocytic differentiation of mesenchymal stem cells
... tenocytic differentiation of mesenchymal stem cells ...tenocytic differentiation through the treatment with growth differentiation factor-7 (GDF-7), which has been reported to induce ...
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Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth
... Efficient delivery of factors to and from the oocyte at crit- ical stages of development is essential for the coordina- tion of oogenesis and folliculogenesis, and is influenced by the structural features of the ...
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Differentiation induction and growth factor responses of murine myeloid leukemias
... Jetten AM, Jetten MER and Sherman MI 1979 Stimulation of several murine embryonal carcinoma cell lines by retinoic acid Experimental Cell Research 124 381 Jones AL and Millar JL 1989 Gro[r] ...
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Activin signaling as an emerging target for therapeutic interventions
... Activin signals are transmitted through two types of trans- membrane serine/threonine kinase receptors, type I and type II activin receptors in target cells [1,4]. Activin recep- tors are prototypes of single-pass ...
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Developmental tumours, early differentiation and the transforming growth factor beta superfamily
... toderm where, probably under influence of hormones such as PTHrP (van de Stolpe et al., 1993; see also Verheijen and Defize, this issue), they differentiate into parietal endoderm (PE). They eventually line the entire ...
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Increased GDF9 and BMP15 mRNA levels in cumulus granulosa cells correlate with oocyte maturation, fertilization, and embryo quality in humans
... of GDF9 and BMP15 mRNAs were logarithmically transformed into a normal ...between GDF9 and BMP15 expression and oocyte developmental potential after age ...compare GDF9 and BMP15 expression in ...
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Cloning and analysis of the rearranged interleukin-3 gene in the leukaemia cell line WEHI - 3B
... independent of M-CSF for their survival and tumorigenic in T cell deficient mice. These cells did not produce M-CSF as indicated by bioassay of culture medium and Northern analysis of mRNA. These workers have suggested ...
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Human infrapatellar fat pad derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor 2
... of differentiation potential. Fibroblast growth fac- tor-2 (FGF-2) is a potent mitogen for a variety of cell types derived from the mesoderm, including chondrocytes ...and differentiation of bone ...
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Salivary Epidermal Growth Factor in Mice Modulates the Differentiation of CD4CELLS in Thymus
... secreted growth factors on differentiation, activation and cellularity of T cell at peripheral region the flow cytometric analysis of CD4 cell from the blood sample was ...
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