Guanine-nucleotide binding proteins
Activation of Escherichia coli heat labile enterotoxins by native and recombinant adenosine diphosphate ribosylation factors, 20 kD guanine nucleotide binding proteins
... 20-kD guanine nucleotide-binding proteins, known as ADP- ribosylation factors or ...These proteins directly activate the CTA1 catalytic unit and stimulate its ADP ribosylation of Gs ...
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The role of the guanine nucleotide binding proteins p21ras in T cell activation and growth
... To express m utant Ras proteins, a CMV expression vector w as constructed to drive expression of viral Harvey ras. Both sense(CMVras+ = CMVv-Ha- ras) and antisense(CMVras-) constructs were isolated. In figure 3.7, ...
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Differential expression of guanine nucleotide binding proteins enhances cAMP synthesis in regenerating rat liver
... Fluctuations in cyclase activity were not explained by variations in glucagon receptor kinetics, but reflected altered G-protein expression. Membrane levels of the stimulatory G- protein, Gs alpha, increased early after ...
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Hobbs_unc_0153D_14172.pdf
... 21-kDa guanine nucleotide binding proteins that function as molecular switches to modulate signaling pathways that control cell growth, differentiation, and apoptosis ...its nucleotide ...
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Guanine nucleotide binding regulatory proteins and dual control of adenylate cyclase
... When the resolved subunits of G0 were tested for their ability to inhibit adenylate cyclase activity in platelet membranes, the inhibitory activity of the "activated" dimer was found to [r] ...
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9-24-2014 12:00 AM The Role Of The RNA-Binding Protein Rho Guanine Nucleotide Exchange Factor In The Cellular Stress Response
... RNA-binding proteins involved in ALS, specifically TDP-43 and FUS, as having stress protective properties through a mechanism of stress granule formation (Higashi et ...
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Hepatitis B virus X protein interacts with β5 subunit of heterotrimeric guanine nucleotide binding protein
... Positive Yeast Colonies with Potential HBX Interacting Proteins. Comparison between control yeast colonies and positive colonies from the library screening that developed blue colour over a 5-day incubation period ...
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Bradykinin activated membrane associated phospholipase C in Madin Darby canine kidney cells
... a guanine nucleotide-binding protein in receptor-mediated activation of PLC, we evaluated the role of guanine nucleotide proteins in receptor-mediated (bradykinin-stimulated) ...
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Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells
... actin-binding proteins like Eplin, vinculin, formin-1 or α-actinin ...a guanine nucleotide exchange factor, as well as the Rac1 effector IQGAP1 has been documented ...eukaryotic ...
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A potential role for guanine nucleotide binding protein in the regulation of endosomal proton transport
... The effects of guanosine 5'-triphosphate (GTP) and GTP-gamma-S, known activators of GTP binding proteins, on proton transport were investigated in endosome-enriched vesicles (endosomes). Endosomes were ...
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Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin and BB/Wor diabetic rats Immunodetection of Gs and Gi with antisera prepared against synthetic peptides
... Adenylate cyclase in liver plasma membranes from streptozotocin-diabetic STZ or BB/Wor spontaneously diabetic rats showed increased responsiveness to GTP, glucagon, fluoroaluminate, and [r] ...
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Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
... eIF2␥ proteins Once bound, the ribosome traverses the mRNA in a 5⬘- is further suggested by genetic and biochemical data to-3⬘ direction and locates the AUG codon representing that indicate the ␥-subunit plays a ...
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Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter.
... The rate of decay of p78 levels in diploid cells after a 24-h treatment with IFN-a was much slower than the rate of decay of the antiviral state against influenza A virus and vesicular s[r] ...
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Mechanism of Nucleotide Exchange by Guanine Nucleotide Exchange Factors on the Ras Superfamily of Small G-Proteins
... A diverse collection of extracellular ligands can stimulate Ras by activating their receptors, such as neurotransmitters, hormones and growth factors causing a transient increase in Ras.GTP levels. Upon stimulation, the ...
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umi-unc-2103.pdf
... My VprBP data are similar, yet not completely overlapping, with these results. Loss of VprBP in p53 wildtype cells did result in p53 accumulation and inhibition of proliferation (Figure 3.8 and 3.9), but we see no ...
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Sirtuins regulate proteomic responses near thermal tolerance limits in the blue mussels Mytilus galloprovincialis and Mytilus trossulus
... metabolic proteins that showed an interaction effect but without a general trend of how HS+suramin affected protein abundance ...trossulus, proteins with decreased abundance under HS +suramin (cluster I) ...
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Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling
... GPR116 proteins within the GAIN domain generates a mature protein, consisting of an N-terminal fragment (NTF) that is noncova- lently linked to the C-terminal fragment (CTF), consisting of a 7 transmembrane (7TM) ...
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Targeting phosphoinositide 3-kinase (PI3K) in head and neck squamous cell carcinoma (HNSCC)
... combination with radiotherapy [27]. Cetuximab is cur- rently used with platinum-based chemotherapy as the first line treatment for HNSCC or for recurrent or metastatic (R/M) disease [28, 29]. However, efforts to develop ...
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RNA binding proteins co-localize with small tau inclusions in tauopathy
... RNA binding proteins (RBPs) that are known markers for stress granules ...tau binding proteins changes with disease in the rTg4510 mouse, and then followed up with immunohistochemistry to ...
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SGK and disrupted renal sodium handling in diabetes
... Foetal cal f serum FMRFamide-gated sodium channel Fura-2 acetyoxymethylderivative Gamma Guanine nucleotide-binding protein Glyceraldehyde 3 phosphate dehyrdogenase Glucose transporter Ga[r] ...
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