Haplotype and nucleotide diversity
Evolutionary Factors Shaping Haplotype and Nucleotide Diversity in Humans and Malaria
... 76 ABSTRACT Recombination acts to create new combinations of alleles and to break up existing associations, and therefore plays an important role in shaping genetic variation and patterns of haplotype structure or ...
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A Soybean Transcript Map: Gene Distribution, Haplotype and Single-Nucleotide Polymorphism Analysis
... Single- nucleotide polymorphisms (SNPs) were discovered via the resequencing of sequence-tagged sites (STSs) developed from expressed sequence tag (EST) ...average nucleotide diversity of u ¼ ...
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Distribution and haplotype diversity of WKS resistance genes in wild emmer wheat natural populations
... paralogue WKS2 are present only in the southern distribu- tion range of wild emmer in the Fertile Crescent, support- ing the idea that wheat domestication occurred in the north- ern populations. An analysis of ...
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Nucleotide Variation and Haplotype Diversity in a 10-kb Noncoding Region in Three Continental Human Populations
... Noncoding regions are usually less subject to natural selection than coding regions and so may be more useful for studying human evolution. The recent surveys of worldwide DNA variation in four 10-kb noncoding regions ...
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Casein haplotype diversity in seven dairy goat breeds
... single nucleotide polymorphisms (SNPs) located within the casein gene cluster were used to characterize the haplotype variability of six southern Italian goat breeds (Girgentana, Maltese, Rossa ...
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Haplotype Diversity in 11 Candidate Genes Across Four Populations
... in haplotype frequencies within and across populations, as both ...Such diversity will influence the choice of ‘‘tagging’’ SNPs for candidate gene or whole-genome association studies because some markers ...
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Methods for Human Demographic Inference Using Haplotype Patterns From Genomewide Single-Nucleotide Polymorphism Data
... the haplotype information ...use haplotype information exclusively to fit a population split followed by growth model, their model is quite restrictive and allows inference only of one free parameter, the ...
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Linkage Disequilibrium Grouping of Single Nucleotide Polymorphisms (SNPs) Reflecting Haplotype Phylogeny for Efficient Selection of Tag SNPs
... Single nucleotide polymorphisms (SNPs) have been proposed to be grouped into haplotype blocks harboring a limited number of ...ethnic diversity by characteriz- ing 979 SNPs distributed throughout the ...
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Mechanisms of haplotype divergence at the RGA08 nucleotide-binding leucine-rich repeat gene locus in wild banana (Musa balbisiana)
... Two clades of genes coexist on the RGA08 cluster with one clade showing a particularly large expansion on one DNA strand. The two types of RGA08 genes likely originated from the same ancestral sequence and followed two ...
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Mechanisms of haplotype divergence at the RGA08 nucleotide-binding leucine-rich repeat gene locus in wild banana (Musa balbisiana)
... Two clades of genes coexist on the RGA08 cluster with one clade showing a particularly large expansion on one DNA strand. The two types of RGA08 genes likely originated from the same ancestral sequence and followed two ...
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A Primary Assembly of a Bovine Haplotype Block Map Based on a 15,036-Single-Nucleotide Polymorphism Panel Genotyped in Holstein–Friesian Cattle
... DISCUSSION This is the first extensive study defining haplotype blocks and haplotype diversity in the bovine genome. We have also identified a set of tag SNPs for these regions, which will be useful ...
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Nucleotide Diversity in Gorillas
... of nucleotide diversity in humans and apes may provide valuable information for inferring the demographic history of these species, the effect of social structure on genetic diversity, patterns of ...
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Low nucleotide diversity in man.
... YOUNG, 1987 Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentia- tion factor (interleukin 5).. FOTHERGILL, 1988 Genomic [r] ...
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Low Nucleotide Diversity in Chimpanzees and Bonobos
... ment of mitochondrial genetic diversity in East African chimpan- Takahata, N., Y. Satta and J. Klein, 1995 Divergence time and zees, Pan troglodytes schweinfurthii. Mol. Biol. Evol. 14: 976–984. population size in ...
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Association of the Single Nucleotide Polymorphism and Haplotype of the Complement Receptor 1 Gene with Malaria
... licenses/by-nc/3.0) which permits unrestricted non- commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose: Although the polymorphisms of erythrocyte ...
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Patterns of Nucleotide Diversity in Wild and Cultivated Sunflower
... of nucleotide diversity in domesticated plant lineages has recently been motivated by the potential for using association-based mapping techniques as a means for iden- tifying the genes underlying complex ...
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Assessing Microbial Diversity Through Nucleotide Variation
... High throughput pyrosequencing analyses of bacterial populations in environmental samples using PCR-‐amplified 16S rRNA gene sequences reveal an enormous diversity of microbes (Sogin et al., 2006). The maximum ...
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Accurate Haplotype Inference for Multiple Linked Single-Nucleotide Polymorphisms Using Sibship Data
... eases. Haplotype-based association studies have been advocated as powerful tools for fine mapping and positional cloning of complex disease ...for haplotype inference using data from relatives were ...
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Recovering Frequencies of Known Haplotype Blocks From Single-Nucleotide Polymorphism Allele Frequencies
... We first discuss an idealized situation, in which SNP haplotypes correspond to nodes in that tree. Each SNP sepa- rates the nodes along exactly one tree branch. Such a tree is allele frequencies are measured with ...
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Single nucleotide polymorphisms and haplotype of CYP2E1gene associated with systemic lupus erythematosus in Chinese population
... We were able to identify four tag SNPs (rs2031920, rs2070672, rs8192772 and rs2480256) by pairwise LD analysis for haplotype inferring. Such detailed informa- tion is a good complementary to the released Phase III ...
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