Hematopoietic stem and progenitor cells
Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells
... of hematopoietic stem and progenitor cells (HSPCs) to mobilize from the bone marrow (BM) is essential for the treatment of patients with hematological malignancies or disorders who undergo ...
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Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells
... Molecular and functional characterization of HuAECs Flow cytometric analysis was used to characterize cell surface markers on the subcultured HuAECs (Fig. 1a), showing that the HuAECs were positive for endothelial cell ...
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Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells
... cell (CFC) (Figure 5E) and SLAM LSK cell (Figure 5F) mobiliza- tion response to G-CSF to the level seen in WT mice. Similarly, coadministration of NPY 3-36 and G-CSF reversed the attenuation of CFC mobilization ...
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Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
... CD34+ cells, which peaked at 60 minutes-post administration and subsided at 120 minutes ...marrow cells was assessed, in which a 60% enhancement of growth was reported ...marrow cells from mice ...
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The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
... epithelial cells in the ...leukemic cells of 90% of patients with acute myeloid leukemia (AML) but not in hematopoietic stem and progenitor cells derived from normal ...murine ...
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Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms
... stromal cells (BMSC) from patients with pre-fibrotic myeloproliferative neoplasms ...normal hematopoietic stem and progenitor cells and displayed increased matrix remodelling (in ...
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Regulation of human hematopoietic stem cell lineage commitment
... My thesis projects focus on identifying and characterizing regulatory factors involved in myeloid commitment steps for human hematopoietic stem and progenitor cells (HSPCs), so as [r] ...
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Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4
... on hematopoietic cell growth and progenitor ...BM cells were iso- lated and infected with Sall4- expressing ...4 cells were mixed with MethoCult ® medium and seeded in dishes for colony ...
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Vol 70, No 3 (2018)
... – hematopoietic stem cells; HSPC − hematopoietic stem/progenitor cells; HOXB4 – homeobox protein Hox-B4; TNC –total nucleated cells; CFU – colony forming unit; MSC ...
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Circulating hematopoietic stem cell count is a valuable predictor of prematurity complications in preterm newborns
... circulating progenitor cells in respiratory system disorder found in neonates born ...+ progenitor cells compared to ...+ cells were correlated with a prolonged duration of mechanical ...
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Functional similarities of microRNAs across different types of tissue stem cells in aging
... tissue stem cells (TSCs) contribute to loss of tissue homeostasis, including re- ductions in lymphopoiesis and the long-term repopu- lating abilities of hematopoietic stem/progenitor ...
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Hematopoietic stem cells from peripheral blood the perspective of non mobilized peripheral blood
... vitro expansion. Results from pilot clinical trials of transplants using expanded UCB-HSC have shown no adverse effects in the patients. However, more clinical trials must be conducted using expanded HSC for guar- ...
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Lentivirus Gene Transfer in Murine Hematopoietic Progenitor Cells Is Compromised by a Delay in Proviral Integration and Results in Transduction Mosaicism and Heterogeneous Gene Expression in Progeny Cells
... Hematopoietic stem cells are an attractive target for gene therapy, as they can both self-renew and differentiate into all blood lineages, thus supporting hematopoiesis throughout the ...into ...
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Cusan, Monica (2012): Studie über das leukämogene Potential der Hoxb4-DeltaProlin Mutante in einem murinen Knochenmarkstransplantationsmodell und den Effekt der Hemmung von Histondeacetylasen in vitro und in vivo. Dissertation, LMU München: Medizinische Fakultät
... of cells with LTC-IC (long-term culture-initiating cells) activity, to promote the development of B cells in vivo, and to increase the number of cells able to repopulate NOD/SCID mice (Buske ...
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Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
... PBCD34+38- cells were enriched for HSCs, these CD34+ cells do not represent a pure population of LTR ...CD34+ cells also occurred in murine LTR HSCs, believing that genes with age-associated ...
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Small RNAs Play Big Roles in Hematopoietic Development
... in hematopoietic cells of myeloid origin have been largely ...in cells of the innate immune system, such as monocytes and macrophages, following exposure to inflammatory stimuli (O'Connell et ...
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Characterization of Hemangioma-initiating Stem Cells
... All cells were plated at 20,000 cells/cm 2 density on 4- or 8-chambered slides for 48 hours prior to staining to allow for ...adherence. Cells were fixed with methanol and then stained for ...
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The role and potential of umbilical cord blood in an era of new therapies: a review
... of cells and to have regenerative potential for many clinical ...UCB-derived cells have become a popular ...UCB-derived cells and the great potential and current clinical applications of UCB in an ...
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Original Article Absence of myocyte regeneration by mobilization of bone marrow stem cells after myocardial infarction
... including hematopoietic and progenitor cells and endothelial progenitor cells (EPC) in bone marrow and peripheral blood ...+ stem cell in bone marrow and ...
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6187.pdf
... 32D/p185 cells treated with Compound A for 12 hours showed decreased levels of both Sod2 and Fth1 mRNAs ...32D/p185 cells. Similar to the results obtained using Compound A treatment, cells expressing ...
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