Herpes virus-2 proteins
Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene
... these proteins is conserved but that the points of contact of the proteins with the compounds are probably ...the proteins with DNA; (iv) interaction of the encap- sidation proteins with the ...
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Diversity of the CD8+ T-Cell Response to Herpes Simplex Virus Type 2 Proteins among Persons with Genital Herpes
... Cytolytic T cells play a major role in controlling herpes simplex virus type 2 (HSV-2) infections in humans. In an effort to more thoroughly evaluate the response to HSV-2 directly, ex ...
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DNA-binding proteins induced by herpes simplex virus type 2 in HEp-2 cells.
... First, mock-infected cell DNA-binding proteins were concentrated from 0.1, 0.3, 0.5, and 1.0 M NaCl eluates from a denatured DNA-cellulose column and subjected to electrophoresis in adja[r] ...
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Comparison of the virion proteins specified by herpes simplex virus types 1 and 2.
... A recent study of the structural polypeptides specified by 53 different HSV-1 strains revealed that certain polypeptide bands with characteristic electrophoretic mobilities in SDS gels w[r] ...
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Neurons differentially control expression of a herpes simplex virus type 1 immediate-early promoter in transgenic mice.
... Some variability in the level of expression between different lines of transgenic mice as was seen in these mice is common (2, 5, 12, 15, 19, 27, 29). The fact that all three of the lines share the key expression ...
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Functional Analysis of the Triplex Proteins (VP19C and VP23) of Herpes Simplex Virus Type 1
... only 2 out of the 23 mutants analyzed had wild-type activity, whereas for VP19C 7 out of the 20 mutants had wild-type activity ...viable virus con- taining an epitope tag after residue 10 of the protein ...
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ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled
... To further explore the requirements of ICP0 in preventing the phosphorylation of Chk1 in response to HU during infec- tion, we used the ICP0-null mutant  , which harbors lacZ insertions in both copies of the ICP0 gene ...
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Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function.
... When we analyzed each of the mutants in a complementation assay for virus function 38, only two mutant proteins, Cys-2 and Cys-4, Glycoprotein D gD of herpes simplex virus HSV is a struc[r] ...
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Recognition of Herpes Simplex Virus Type 2 Tegument Proteins by CD4 T Cells Infiltrating Human Genital Herpes Lesions
... Definition of additional T-cell epitopes in tegument protein VP16. We previously found three epitopes within VP16 (Table 3), all HSV-2 type specific (14), and detected proliferative responses to full-length VP16 ...
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Dynasore Disrupts Trafficking of Herpes Simplex Virus Proteins
... Dynasore blocks HSV-1 and HSV-2 entry and nuclear trans- port in human neuronal cells. To determine whether the inhibi- FIG 3 Dynasore blocks HSV-1 and HSV-2 entry into human neuronal cells. (A) SK-N-SH ...
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The Interaction between the Major Capsid Protein and the Smallest Capsid Protein of Human Cytomegalovirus Is Dependent on Two Linear Sequences in the Smallest Capsid Protein
... of herpes simplex virus type 1 (HSV-1) have indicated that the mature virion capsid of this virus is composed primarily of four viral proteins (5, 10, 12, 13, 16, 19, ...these proteins, ...
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Herpes Simplex Virus Type 2 Glycoprotein G-Negative Clinical Isolates Are Generated by Single Frameshift Mutations
... simplex virus (HSV) codes for several envelope glycoproteins, including glycoprotein G-2 (gG-2) of HSV type 2 (HSV-2), which are dispensable for replication in cell ...such ...
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Mutation of Neuraminidase Cysteine Residues Yields Temperature-Sensitive Influenza Viruses
... mutant proteins were ts in their transport and/or ...minus virus at ...gD-minus virus at 37°C ...cell proteins and for binding to the ␣TIF response ...wild-type virus at nonpermissive ...
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Inhibition of Curcumin Treated Herpes Simplex Virus 1 and 2 in Vero Cells
... A recombinant strain of HSV-1, GHSV-UL46, which contains the sequence for green fluorescent protein (GFP) fused to the tegument protein pUL46 (ATCC, Manassas, VA, USA) and HSV-2VP26-GFP which expresses a fusion protein ...
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Popa, Mirela (2010): Genetic analysis of the mouse cytomegalovirus nuclear egress complex. Dissertation, LMU München: Fakultät für Biologie
... the virus genome and subsequent steps of maturation, such as nuclear egress of the DNA-filled ...HCMV proteins UL51, UL52, UL77 and UL93, which are homologous to the herpes simplex virus type ...
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Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.
... Characterization of an aphidicolin-resistant mutant of herpes simplex virus type 2 which induces an altered viral DNA polymerase.. Drug-resistant mutants of herpes simplex virus type 2 w[r] ...
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Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice
... With the recent findings of HSV DNA in the CNS of pa- tients dying without encephalitis (2, 43, 68), it became impor- tant to determine whether i.c. injection of G207 might lead to reactivation of or recombination ...
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Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report
... We then hypothesized an astrovirus-related CNS in- fection and tested the initially obtained CSF sample for the virus. Sanger sequencing revealed a classic genotype HAstV-1 with the same nucleotide sequence in ...
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Glycoprotein Bb, the N-terminal subunit of bovine herpesvirus 1 gB, can bind to heparan sulfate on the surfaces of Madin-Darby bovine kidney cells.
... tural proteins, among which there are at least nine membrane- associated glycoproteins (1, 6, 15, 16, 18, 25, 29–31, ...the virus entry process ...for herpes simplex virus 1 (HSV-1) and a ...
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Identification and typing of herpes simplex virus by enzyme immunoassay with monoclonal antibodies
... Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: comparison with type-specific rabbit antisera and restriction end[r] ...
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