Herpesvirus saimiri
trans activation of the thymidylate synthase promoter of herpesvirus saimiri.
... Here we describe the regulation of the herpesvirus saimiri TS gene that is increasingly expressed from delayed-early to late times of virus infection and identify a genomic upstream regi[r] ...
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Herpesvirus ateles DNA and Its Homology with Herpesvirus saimiri Nucleic Acid
... 361-373 Copyright 0 1978 American Society for Microbiology Herpesvirus ateles DNA and Its Homology with Herpesvirus saimiri Nucleic Acid Received for publication 1 July 1977 Analysis of [r] ...
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Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488.
... Rat-STP-C488 cells, COS-1 cells transfected with plasmid pSVL-STP-C488, and common marmoset T lymphocytes immortalized by herpesvirus saimiri strain 488 all showed the presence of this p[r] ...
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A Role for Herpesvirus Saimiri orf14 in Transformation and Persistent Infection
... The product of open reading frame 14 (orf14) of herpesvirus saimiri (HVS) exhibits significant homology with mouse mammary tumor virus superantigen. orf14 encodes a 50-kDa secreted glycoprotein, as shown ...
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Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity
... The herpesvirus sai- miri ORF71 encoding the vFLIP was deleted by a cosmid- based approach that allows the construction of recombinant viruses without contaminating wild-type ...of herpesvirus ...
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STP and Tip Are Essential for Herpesvirus Saimiri Oncogenicity
... Herpesvirus saimiri (HVS), a gamma-2 herpesvirus or rhadi- novirus, infects most squirrel monkeys without apparent dis- ease (9, 13). In other nonhuman primates, however, HVS in- duces rapidly fatal ...
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Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation.
... Previous studies have identified a region of the herpesvirus saimiri genome required for immortalization of marmoset lymphocytes in vitro and for oncogenicity in vivo; this region is not[r] ...
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Primary structure of the herpesvirus saimiri genome.
... Sequence homology of herpesvirus saimiri-encoded proteins and cellular proteins ORF Designation 01 02 04 a/b STP-A DHFR CCPHb 14 TS ECLF2 ECRF3 References Amino acid sequence identity Fu[r] ...
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The Interleukin-17 Gene of Herpesvirus Saimiri
... formed to demonstrate vil-17 transcripts of wild-type herpesvirus saimiri C488. Protected fragments were observed in RNA samples from lytic cultures only. The signal was observed in virus-producing ...
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Growth Transformation of Human T Cells by Herpesvirus Saimiri Requires Multiple Tip-Lck Interaction Motifs
... double-mutant herpesvirus saimiri C488 ⌬ CSKH mSH3B induced smaller aggregates, and these cultures contained large amounts of cell debris ...by herpesvirus saimiri C488 depended on Tip-Lck ...
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Solubilization and characterization of Herpesvirus saimiri-induced membrane antigens.
... The 852 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Treatment of Herpesvirus saimiri HVS-infected owl monkey cells by limited papain digestion removed the HVS-induc[r] ...
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Mapping of Functional Domains in Herpesvirus Saimiri Complement Control Protein Homolog: Complement Control Protein Domain 2 Is the Smallest Structural Unit Displaying Cofactor and Decay-Accelerating Activities
... 10299 Downloaded from http://jvi.asm.org/ on November 8, 2019 by guest Herpesvirus saimiri encodes a functional homolog of human regulator-of-complement-activation proteins named CCPH th[r] ...
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Analysis of herpesvirus saimiri structural proteins with monoclonal antibodies.
... 140 and 120 kilodaltons are defined by the rabbit sera arrowheads, lane 2, and that neither is present in nontreated infected cells, since the antigens of corresponding size that are pre[r] ...
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Terminal repetitive sequences in herpesvirus saimiri virion DNA.
... The structural features of repeat DNA sequences at the termini of intact virion M-DNA 160 kilobases and orientation of reiterated DNA were analyzed by radioactive end labeling of M-DNA, [r] ...
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The Insulator Protein CTCF Binding Sites in the orf73/LANA Promoter Region of Herpesvirus Saimiri Are Involved in Conferring Episomal Stability in Latently Infected Human T Cells
... Herpesviruses establish latency in suitable cells of the host organism after a primary lytic infection. Subgroup C strains of her- pesvirus saimiri (HVS), a primate gamma-2 herpesvirus, are able to ...
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Organization of the thymidylate synthase gene of herpesvirus saimiri.
... pseudorabies virus 69% 19, and human cytomegalovirus 56% 13, did not induce TS activity in permissive cells during virus replication 22, and no nucleotide or amino acid sequence homology[r] ...
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Structural proteins of Herpesvirus saimiri.
... For the polypeptides, the following criteria were applied: i presence of the protein in the purified virion preparation, ii absence of a polypeptide that could be labeled with radioactiv[r] ...
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Immediate-early transcription of Herpesvirus saimiri.
... D 32P-labeled cDNA was synthesized from early RNA 20 h postinfection with calf thymus DNA as a random primer and hybridized with OMK cell DNA cleaved by Hindlll lane 1, the cloned EcoRI [r] ...
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Repetitive sequences in complete and defective genomes of Herpesvirus saimiri.
... DNA infectivity studies by using the calcium phosphate and the DEAE-dextran method gave further evidence that H genomes are defective: no infectious virus was recovered from permissive c[r] ...
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Expression of collagenlike sequences by a tumor virus, herpesvirus saimiri.
... A bicistronic viral mRNA from this region is transcribed in tumor cells transformed by a highly oncogenic group C virus.. The first open reading frame is homologous to collagen; no such [r] ...
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