High-throughput sequencing
Indices and Applications in High-Throughput Sequencing
... 8 Conclusion and Future Work In this thesis, we presented data structures and algorithms with applications in the anal- ysis of high-throughput sequencing data. We developed a uniform framework for ...
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Standards for Sequencing Viral Genomes in the Era of High Throughput Sequencing
... to high-throughput sequencing technologies, genome sequencing has become a common component in nearly all aspects of viral research; thus, we are experiencing an explosion in both the number ...
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Universal Count Correction for High-Throughput Sequencing
... Discussion We have shown that per-base count overdispersion is a widespread and consistent phenomenon in high-throughput sequencing experiments. While correcting for exon-level over- dispersion has ...
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High-throughput sequencing of the chicken gut microbiome
... limited high- throughput sequencing of the microbial communities colonising the organs that form the proximal chicken gut— almost all previous studies have focussed on the small intestine and ...
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Performance comparison of benchtop high-throughput sequencing platforms
... bench-top high-throughput sequencing instruments are now ...by sequencing isolates of Escherichia coli O104:H4 from the German outbreak of ...analysing throughput, read length, read ...
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High throughput sequencing to decipher the genetic heterogeneity of deafness
... laboratories on a routine basis? What are the ethical considerations involved? Much of the eff ort invested in the fi eld of genomics aims to improve medical strategies in diagnostics, treatment, cure and prevention of ...
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Validation of high throughput sequencing and microbial forensics applications
... High throughput sequencing (HTS) generates large amounts of high quality sequence data for microbial ...2) sequencing, and 3) data ...
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High-throughput sequencing of cytosine methylation in plant DNA
... Despite the progress being made in analysis of high- throughput sequencing data and specifically that pertain- ing to the methylome, there exist some clear areas for improvement. The question of ...
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Read Annotation Pipeline for High-Throughput Sequencing Data
... Furthermore, we can incorporate additional filters into the pipeline to better determine the origin of mappings. In our experiment, we only used the Unique and Quality filters as informative filters. This resulted in ...
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High-throughput sequencing and small non-coding RNAs
... Sanger sequencing (see Figure ...of high-throughput sequencing (HTS) provides a new technique allowing the measurement of millions of these RNA snippets in short time and low- ...used ...
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The Role of High Performance, Grid and Cloud Computing in High-Throughput Sequencing
... perform high-throughput sequencing experiments, which can generate enormous ...HTS sequencing data it is considered to be characterized as Big Data, and as with such examples there lies a ...
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Analysis options for high throughput sequencing in miRNA expression profiling
... miRNA expression profiling guidelines In a summary of the results we propose a guidance for miRNA expression profiling techniques. For experiments with aim of differential expression measurements we propose the ...
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Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis
... A high-throughput sequencing strategy of 12 genes linked to HLH was validated in 13 patients with previously identified HLH-associated mutations and prospectively evaluated in 58 HLH ...
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Characterization of a new apple luteovirus identified by high throughput sequencing
... viruses. High-throughput sequencing and analyses Total RNAs of three pooled samples, CPAR (all 6 root- stock samples), CPAS1 (scion samples of PA2, PA4 and PA5) and CPAS2 (scion samples of PA7–9), ...
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Assessing Illumina technology for the high throughput sequencing of bacteriophage genomes
... 5 Warwick Medical School, University of Warwick, United Kingdom ABSTRACT Bacteriophages are the most abundant biological entities on the planet, playing crucial roles in the shaping of bacterial populations. Phages have ...
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Identification of microRNAs and their targets in Finger millet by high throughput sequencing
... allowing sequencing of RNA population on massive ...RNA sequencing was per- formed to identify the complete set of conserved and novel ...2006b). Sequencing frequency in high throughput ...
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Characterizing the human vaginal microbiome using high-throughput sequencing
... using high-throughput sequencing methodologies to describe the vaginal ...V6 sequencing in order to describe the vaginal profiles of HIV+ African women with and without BV (48, ...using ...
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Genotype-Frequency Estimation from High-Throughput Sequencing Data
... improving high-throughput sequencing technologies provide unprecedented opportunities for carrying out population-genomic studies with various ...from sequencing errors and biparental ...
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Applications of High-Throughput Sequencing Data Analysis in Transcriptional Studies
... a high-throughput sequencing (HTS) method for transcriptome anal- ysis, has been successfully used on many of these mouse models, enabling global analyses of specific genomic alterations at a ...
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Probabilistic methods for quality improvement in high-throughput sequencing data
... next-generation sequencing (NGS) technologies, that are capable of generating millions of sequences at only a tiny fraction of cost than a decade ago [van Dijk et ...Affordable high-throughput ...
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