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Higher Order Chromatin Structure

Linker histone epitopes are hidden by in situ higher-order chromatin structure

Linker histone epitopes are hidden by in situ higher-order chromatin structure

... situ chromatin higher- order structure, which is destroyed by the sonication step in ...of higher-order chromatin structure at that particu- lar site, but does not ...

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Remodeling of higher order chromatin structure by the JIL 1 histone H3 kinase in Drosophila

Remodeling of higher order chromatin structure by the JIL 1 histone H3 kinase in Drosophila

... euchromatic structure, we ectopically targeted JIL-1 using a LacI/lacO tethering ...in higher order chromatin structure from a condensed heterochromatin-like state to a more open ...

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EZH2-dependent chromatin looping controls INK4a and INK4b , but not ARF , during human progenitor cell differentiation and cellular senescence

EZH2-dependent chromatin looping controls INK4a and INK4b , but not ARF , during human progenitor cell differentiation and cellular senescence

... In order to investigate the three-dimensional con- formation of the INK4b-ARF-INK4a locus, we used chro- matin conformation capture (3C) technology in combination with qPCR ...locus higher-order ...

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p63 and Brg1 control developmentally regulated higher order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells

p63 and Brg1 control developmentally regulated higher order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells

... including higher- order chromatin folding and three-dimensional (3D) genome organisation, play an important role in the control of gene ...the higher-order chromatin ...

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Maintenance of Heterochromatin by the Large Subunit of the CAF-1 Replication-Coupled Histone Chaperone Requires Its Interaction with HP1a Through a Conserved Motif

Maintenance of Heterochromatin by the Large Subunit of the CAF-1 Replication-Coupled Histone Chaperone Requires Its Interaction with HP1a Through a Conserved Motif

... into chromatin regulates many biological processes, from the control of gene expression to the regulation of chromosome ...this structure upon cell division is therefore of prime importance during ...

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Chromatin state analysis of the barley epigenome reveals a higher order structure defined by H3K27me1 and H3K27me3 abundance

Chromatin state analysis of the barley epigenome reveals a higher order structure defined by H3K27me1 and H3K27me3 abundance

... in Figure S1. Different distribution profiles are apparent, and we grouped these into four classes. Class I modifica- tions (H3K4me3, H3K56ac, H3K27me3) show high peak densities towards the telomeres and low densities in ...

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Estrogen induced chromatin decondensation and nuclear re organization linked to regional epigenetic regulation in breast cancer

Estrogen induced chromatin decondensation and nuclear re organization linked to regional epigenetic regulation in breast cancer

... local chromatin struc- ture [51], the ER has also been shown to visibly de- compact large-scale chromatin architecture by recruiting coactivators ...on chromatin structure is further than ...

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Comprehensive analysis of promoter proximal RNA polymerase II pausing across mammalian cell types

Comprehensive analysis of promoter proximal RNA polymerase II pausing across mammalian cell types

... In order to better refine the roles of RNAP2 pausing on regulating gene expression and chromatin structure, we performed a comprehensive analysis of promoter- proximal RNAP2 accumulation across ...

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Sparse conserved under methylated CpGs are associated with high order chromatin structure

Sparse conserved under methylated CpGs are associated with high order chromatin structure

... loops to associate scUMCs with scUMC-target genes. If the mate of an anchor region containing a scUMC overlapped with the promoter region (±3 kb from TSS) of a gene, it was considered the scUMC-target gene. We used ChIA- ...

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The expanding repertoire of hereditary information carriers

The expanding repertoire of hereditary information carriers

... that chromatin contains genomic regions that are organized into topologically associating domains (TADs), within which DNA preferentially interacts with itself, as well as DNA loops that bridge functional DNA ...

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Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization

... compact chromatin conformation of ...of chromatin structure to influence RNA processing steps (Mathieu and Bouche 2014), and furthermore, links between nuclear bod- ies and a variety of RNA processing ...

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A nonstandard higher-order variational model to speckle noise removal and thin-structure detection

A nonstandard higher-order variational model to speckle noise removal and thin-structure detection

... In this paper, we have presented a new approach to restore images corrupted by speckle multiplica- tive noise. The proposed approach combines the advantages of the topological gradient method for important feature ...

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piRNA clusters and open chromatin structure

piRNA clusters and open chromatin structure

... 142 regions have been identified as piRNA clusters [22]. Although these sites account for less than 5% of the as- sembled genome, over 90% of all sequenced piRNAs can be derived from these regions [25]. The piRNA ...

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Chromatin structure and DNA damage repair

Chromatin structure and DNA damage repair

... UV irradiation not only causes an increase of H2A ubiqui- tination, but also induces a temporary H3 and H4 ubiqui- tination [89]. A complex containing UV-DDB and CUL4A was required for this ubiquitination. H3 and H4 ...

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Constructing higher-order hydrodynamics: The third order.

Constructing higher-order hydrodynamics: The third order.

... first order in ...third order for neutral fluids in four dimensions, thus finding the most general next-to-leading- order corrections to the relativistic Navier-Stokes ...

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Higher Education—Educating for Higher Order Skills

Higher Education—Educating for Higher Order Skills

... The rationale for the development of the course “Design of computer-based games and interactive stories” was to provide a motivating and engaging context for exercising various higher- order cognitive ...

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First Order Reasoning for Higher Order Concurrency

First Order Reasoning for Higher Order Concurrency

... In the meta-theory and applications we will confine our attention to relations over configurations which have the same acon components. These are relations that have been generated by source-level processes with no ...

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Trypanosoma brucei RRM1 Is a Nuclear RNA Binding Protein and Modulator of Chromatin Structure

Trypanosoma brucei RRM1 Is a Nuclear RNA Binding Protein and Modulator of Chromatin Structure

... It has been shown that depletion of PTB2 causes major changes to the transcriptome, particularly mRNAs with C-rich splice sites (5). Since TbRRM1 and PTB2 interact, we attempted to compare the data sets. This was ...

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Higher order Maass forms

Higher order Maass forms

... For the modular group Γ mod = PSL 2 (Z) the space hom( Γ mod , C) is zero. Hence it does not accept higher order invariants. For the commutator subgroup Γ com = [ Γ mod , Γ mod ] we will employ three di ff ...

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Higher-order Nielsen numbers

Higher-order Nielsen numbers

... In these papers, higher-order Nielsen numbers are not explicitly defined (except for [8], see the comment in the end of the paper). However, they all contribute to the problem of finding the lower estimate ...

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