Histocompatibility Antigens
Expanding the immunotherapeutic potential of minor histocompatibility antigens
... Minor histocompatibility antigens (mHAgs) selectively expressed by cells or cell subsets of the hematopoietic system are targets of the T cell–mediated graft-versus-leukemia response that develops following ...
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Lifting a tip of the veil of human minor Histocompatibility antigens.
... Van Eis C, Bakker A, Zwinderman AH, Zwaan FE, van Rood JJ, Goulmy Ε (1990a) Effector mechamsms in GvHD in response to minor Histocompatibility antigens I Absence of correlation with CTLs[r] ...
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New strategies in identification and quantification of minor histocompatibility antigens
... recognize antigens that are selectively expressed on tumor cells ...minor histocompatibility antigens (MiHA) and peptides arising from ARFs, the commonly used protein databases like UniProt [17], IPI ...
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HLA class II restricted minor histocompatibility antigens - identification, processing and biology
... minor histocompatibility antigens (MiHA) 29 ...recognizing antigens with restricted tissue distribution and therefore allows specific targeting of malignant hematopoietic cells without inducing ...
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Histocompatibility Antigens and Spondylitis
... Professor of Surgery and Microbiology, Medical College of Virginia, Health Sciences Division of Virginia Commonwealth University, l/{ichmond.. RODERICK MACDONALD, M.D.[r] ...
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Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens.
... For greater numbers of antigens associated with the +-haplotype than the t-haplotype (a > b), increased expression of incompatibility in +/t mothers promotes the pr[r] ...
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Conservation of minor Histocompatibility antigens between human and non-human primates.
... served in evolution [8] Howevei until now no lnioima- tion existed on the evolutionary conseivation of human non-sex hnked mHag In the present study we investig ated whether the human no[r] ...
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Human minor Histocompatibility antigens.
... For over five decades minor histocompatibility (mH) antigens have contmued to fascmate immimologists, mainly because of their minor but distinct role in transplantation but no less becau[r] ...
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Paleoserologic Studies: ABO and Histocompatibility Antigens in Mummified American Indians
... Since retrospective paleoserologic studies of human populations using their remains are possible only when A BO groups are present on tissue cells of the organs, th[r] ...
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Acquired tolerance for minor Histocompatibility antigens after HLA identical bone marrow transplantation.
... PBL of patients after HLA-identical BMT are known to contam CTLs reactive to host mH antigens present on patients' pre-transplant PBL (6,8) The observation that skin cells of a healthy f[r] ...
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Characterization and recognition of minor histocompatibility antigens
... To molecularly characterize the MiHA that were targeted by the isolated T-cell clones, we applied whole genome association scanning (WGAs) to detect MiHA-encoding single nucleotide polymorphisms (SNPs). T-cell clones ...
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Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma
... MHC antigens and among them, three poorly differentiated human HCC cell lines also express class II MHC ...MHC antigens expressed by the human HCC cell lines and by a human B lymphoblastoid cell line ...II ...
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Minor Histocompatibility antigens in man and their role in transplantation.
... associdtion between the HA 1,2,4 and 5 incompatibilities and the occurrence of GvHD Now that we have investigated almost twice the number of donor/recipient pairs, the latter correlation[r] ...
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Recognition of Hapten Modified Cells In Vitro by Human T Lymphocytes
... To examine whether a component of secondary proliferative responses was not dependent upon autologous histocompatibility antigens on lymphoid cells, primed responder cells were restimula[r] ...
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Transcriptional and posttranscriptional regulation of class I major histocompatibility complex genes following transformation with human adenoviruses.
... Tumorigenicity of hamster and mouse cells transformed by adenovirus type 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.. The [r] ...
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A General Theory of Autoimmune Disease Causation: Integrating Innate and Adaptive Immunity, Altered Antigen Processing, Sex and Genetic Predispositions, and Microbiome Effects.
... initiating antigens, this synergistic activation of innate immunity becomes ...which antigens stimulate an immune response explaining how genetics also modifies ...the antigens of the microbiome and ...
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Impairment of monocytic function during Trypanosoma cruzi infection.
... Finally, infected clone 53 showed a decreased ability to present antigen to major histocompatibility complex-matched T cells, which may relate to the absence of Class II antigens or to a[r] ...
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Lack of effect of mouse adenovirus type 1 infection on cell surface expression of major histocompatibility complex class I antigens.
... I antigens present on the surface prior to infection remained at high levels and thus obscured detection of the effects of infec- tion on the synthesis, transport, and surface expression of newly synthesized class ...
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v-rel induces expression of three avian immunoregulatory surface receptors more efficiently than c-rel.
... In this study, we demonstrated that three avian immunoregulatory receptors, major histocompatibility MHC antigens class I and class II as well as the interleukin-2 receptor IL-2R, were i[r] ...
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Sequence and genetic organization of adenovirus type 35 early region 3.
... We had previously identified an Ad35 29-kilodalton kDa early glycoprotein which, analogous to group C Ad2 E3-19K, associated with major histocompatibility complex class I antigens in the[r] ...
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