Histone H3 and H4
Acetylated Histone H3 and H4 Mark the Upregulated LMP2A Promoter of Epstein-Barr Virus in Lymphoid Cells
... acetylated histone H3 (AcH3), acetylated histone H4 (AcH4), and H3K4me2 at LMP2Ap in well-characterized type I (Mutu- BL-I-Cl-216 and Rael) and type III (Mutu-BL-III-Cl-99 and CB-M1-Ral-STO) ...
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JMJD1B, a novel player in histone H3 and H4 processing to ensure genome stability
... synthesized histone matura- tion by exploiting the knockdown of JMJD1B by treat- ing HeLa cells with siRNA against JMJD1B (siJMJD1B) and observed the reduction of both JMJD1B protein on cytosolic extracts ...
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Induction of Apoptosis and Acetylation of Histone H3 and H4 by Arctigenin in the Human Melanoma Cell Line SK MEL 28
... arctigenin, histone acetylation status in- creased after 48 hours of treatment to SK-MEL-28 ...of histone H3 at lysine 9 and H4 at lysine 8 was also involved in the regulation of transcription ...
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Tousled kinase TLK1B counteracts the effect of Asf1 in inhibition of histone H3–H4 tetramer formation
... a histone H3–H4 chaperone [16] that is essential in mammalian cells [17] and other organisms [18] but not in yeast, although yeast cells deleted for Asf1 are sen- sitive to genotoxins ...
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Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae
... of histone mutants and a wild type HTA2-HTB2 on a centromeric plasmid, we defined a mutant as “lethal” if it failed to grow on medium containing 5-FOA at 30° for 3 days after ...the H3/4 library (22/592 of ...
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Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity
... acetylated histone H3 and H4 levels in SCC VII cells after 24 hour treatment, suggesting that RRx-001 regulates global acetylation in cancer ...
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Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth
... histones H3 and H4 protein levels after 24 h of treatment, which could result in cell cycle ...of histone mRNA synthesis, was related to cell cycle arrest in MCF-7 cells after treatment with SAHA ...
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HAT1 signaling confers to assembly and epigenetic regulation of HBV cccDNA minichromosome
... B histone acetyltransferase, displaying a crucial role in the deposition of histone H3/H4 onto newly replicated DNA to form nucleosome [21, ...
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Maintenance of Heterochromatin by the Large Subunit of the CAF-1 Replication-Coupled Histone Chaperone Requires Its Interaction with HP1a Through a Conserved Motif
... a histone chaperone that assembles histone H3-H4 dimers onto newly synthesized DNA (Smith and Stillman ...in H3-H4 dimer deposition dur- ing DNA replication (Tyler et ...
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Global Replication-Independent Histone H4 Exchange in Budding Yeast
... the histone chaperones Asf1, CAF-1, and Hir1 do not individually make extensive contribu- tions to chromatin assembly in ...dividual histone chaperones (17, 19, ...to histone exchange within the ORFs ...
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Extracellular Histones Inhibit Efferocytosis
... histones H3 or H4, but not histone H1. Histone H3 demonstrated direct binding to macrophages, an effect that was diminished by preincubation of macrophages with the opsonins growth ...
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Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
... in histone H3/H4 acetylation and histone H3 lysine 4 (Lys4) methylation within the Hoxa7 and Hoxa9 promoters provides an epigenetic mechanism by which this overexpression occurs in vivo ...
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Establishment of Murine Cytomegalovirus Latency In Vivo Is Associated with Changes in Histone Modifications and Recruitment of Transcriptional Repressors to the Major Immediate-Early Promoter
... against histone H3, histone H4, acetylated histone H3 (Ac-H3), or acetylated histone H4 (Ac-H4), followed by quantitative real-time PCR with ...
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Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica
... H2B, H3 and ...of histone acetyltransferases (HATs) or lysine or arginine methyl transferases (HKMTs or PRMTs), respect- ively ...I histone deacetylase (HDAC) ...of histone H3 are the ...
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Expression analysis of histone acetyltransferases in rice under drought stress
... histones H3 and H4 were detected using commercial antibodies and secondary antibodies from Cell Signaling and Millipore (Table ...2.2). Histone H3 was used as an equal loading ...
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The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability
... importantly histone octamers were not even formed with the H4 G94P ...of H4 forms a parallel β sheet with H2A in the nucleosome, which is involved in the docking of H2A/H2B dimers to the ...
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A Simple Method to Produce Sub Nucleosome Complexes of High Purity In Vitro
... modifiers, histone variants, histone post-transl- ational modifications and their cross-talk, it is essential to validate these findings and interactions in vitro for which pure histone complexes are ...
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Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients
... (P=0.0414). Further subgroup analysis based on the TNM stage indicated that patients with TNM stage (II+III+IV), have significantly high expression of both these proteins than patients from TNM stage (I) subgroup ...
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Original Article The toxic effects of a plasticizer, dibutyl phthalate, on rat testis
... of H3 histone was measured with immunohistochemistry and ...of H3 histone ex- pression were significantly different between control group and each DBP group ...of H3 histone, ...
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Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing
... tive H3 reads per peak compared with H3K27me3 peak regions, making the allele-specific analysis ...three histone marks examined (Additional file 1: Figure ...
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