HLA class I genes
HLA and proteasome expression body map
... non-classical HLA class I gene and was first described to bind the activating and inhibitory NK cell receptors (namely CD94/NKG2C and CD94/NKG2A), suggesting a regulatory function to NK cells ...
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Diversity and Frequencies of HLA Class I and Class II Genes of an East African Population
... of HLA class I and class II genes of more than 2000 women from Kenya, eastern Tanzania and southern Uganda around Lake Victoria and analyzed their allele, phenotype and haplotype ...
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Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese
... Europeans, HLA-DRB1*03:01 has been reported to be significantly associated with NMOSD from a whole- genome sequencing study ...tion, HLA-DRB1*16:02 and HLA-DPB1*05:01 have been reported to be ...
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Influence of HLA Class I and HLA-KIR Compound Genotypes on HIV-2 Infection and Markers of Disease Progression in a Manjako Community in West Africa
... A total of 513 samples from HIV-2-infected and uninfected adults, predomi- nantly of the Manjako tribe, were typed for HLA class I (HLA-A, -B, and -C) and KIR genes. Table 1 shows the ...
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No Evidence of Autoimmunity in 6-Year-Old Children Immunized at Birth With Recombinant Hepatitis B Vaccine
... (HLA) class I and II genes, augments the probability of developing an autoimmune disorder after a triggering vaccination, as largely debated, we investigated the fre- quency of autoantibody ...
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HLA class I alleles frequencies in the Syrian population
... The HLA system consists of two classes: class I region contains HLA-A, HLA-B and HLA-C genes and class II region contains HLA-DR, HLA-DQ and ...
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Association of HLA class I and II genes with cutaneous leishmaniasis: a case control study from Sri Lanka and a systematic review
... the HLA poly- morphism in cases and controls ...assessed HLA poly- morphism in visceral leishmaniasis including a large scale multicentre study in Brazil and India [45], but not for cutaneous ...no ...
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The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
... HLA genes encode numerous molecules including the HLA class I and II molecules, which have immunologi- cal ...with HLA-DRB1*1501 and nega- tively associated with ...
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HLA and migraine genes
... and I reported for the first time the molecular analysis of DRB1 and DQB1 alleles in Italian subjects affected by migraine ...that HLA class II DR2 antigen shows a decreased frequency in MWA compared ...
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Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression
... and HLA class I molecules in our Swiss cohort (n ⫽ 84), we studied three immunogenic genes (HIV gag, pol, and nef) encoding 54 epitopes, defined from the Los Alamos Da- ...within ...
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Prognostic value of HLA class I expression in patients with colorectal cancer
... (<12), HLA class I expression level, and adjuvant chemotherapy) and clinical outcome (disease-free survival: ...the HLA class I expression level and clinicopathological ...
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The source of HLA molecules on platelets: Does platelets adsorb soluble HLA molecules from their environment?
... the HLA class I molecules are related to platelets ...of HLA molecules is well described in white blood cells, while in other types of cells, such as platelets, it is not clear yet ...to ...
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Elevated serum HLA class I levels coincide acute and chronic graft-versus-host disease
... Changes in sHLA-I levels during different complications were analyzed in the MANOVA analysis as described in the Material and methods section. The results from the MANOVA analysis are summarized in Table 4. ...
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Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants
... particular HLA class I allele and the presence of an escape variant was first estab- ...the HLA class I molecule required for a response against the epitope, it was concluded, on ...
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HLA class I deficiencies due to mutations in subunit 1 of the peptide transporter TAP1
... (Promix; Amersham, Little Chalfont, United Kingdom), and washed and chased in com- plete RPMI 1640 for different times (1b). All subsequent steps were performed on ice or at 4°C. After centrifugation, cell membranes were ...
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Human leukocyte antigen class 1 genotype distribution and analysis in persons with active tuberculosis and household contacts from Central Uganda
... agents. HLA diversity plays a crucial role in the host-pathogen interaction and can affect the rates of disease acquisition and outcome ...individual’s HLA profile can determine resistance or susceptibility ...
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Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells
... proteome following MVA.HIVconsv infection and the resulting altered self-peptidome associated with the HLA class I molecules, proteomes and immunopeptidomes of uninfected and MVA. HIVconsv-infected ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... 100 class I genes to be characterized due to their nonclassical function and thus their decreased likelihood of being critical determinants of transplant ...L genes as nonclassical is the fact ...
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Induction of HLA class I and class II expression in human T-lymphotropic virus type I-infected neuroblastoma cells.
... To determine whether cell-cell contact was required for HTLV-I infection and induction of HLA expression, neuroblastoma cells cocultured with unirradiated HUT-102 cells were placed in a [r] ...
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Mapping the Landscape of Host-Pathogen Coevolution: HLA Class I Binding and Its Relationship with Evolutionary Conservation in Human and Viral Proteins
... of HLA binding preferences has been driven by the sequence diversity of short segments of relevant pathogenic proteins presented by HLA molecules to the immune ...in HLA binding preferences, we ...
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