HOX genes
The puzzle of Hox genes
... Int I De> Bini 38 557 56 1( 199~) 557 Relliew The puzzle of Hox genes ANDRES E CARRASCO' and SILVIA L LOPEZ Laboratorio de Embriologia Molecular, Insrituto de 8;010gla Celular, Facultad de Medicina, U[.] ...
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Contribution of Hox genes to the diversity of the hindbrain sensory system
... where Hox genes positively influence the specification of Mash1-dependent noradrenergic interneurons, Ubx suppresses the differentiation of progenitors or proneural clusters into sensory ...Drosophila ...
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Role of HOX Genes in Stem Cell Differentiation and Cancer.
... 2.1.2. HOX Genes in ...that HOX genes promote AML development by form- ing chimeric fusions with other ...fusion genes induced long-term proliferation and blocked differenti- ation of ...
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Human malformations caused by mutations in the 5' Hox genes
... vertebrate Hox genes in the control of cell ...non-paralogous Hox genes in combination has also shown that there are likely to be complex interactions between different Hox proteins, as ...
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How Hox genes can shed light on the place of echinoderms among the deuterostomes
... the genes is available only for echinoids, see Table 1), it is likely that the cluster exhibits the same pattern of disorder at the base of the ...of Hox genes in crinoids, which are the most basal ...
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Interplay between activin and Hox genes determines the formation of the kidney morphogenetic field
... that Hox genes regulate the specification of regional identity along the embryonic A-P axis and therefore also the positioning of structures along this ...that Hox genes play during kidney ...
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HOX genes in ovarian cancer
... these genes is an early step in epithelial ovarian neoplasia as they induce aberrant epithelial ...the HOX genes which normally regu- late Müllerian duct differentiation were not expressed in normal ...
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Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth
... clustered genes identified an indirect effect of Hox genes on the maintenance of AER-FGFs but the respective function of Shh and Hox genes in this process remains ...uncoupling ...
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Hox genes regulate the onset of Tbx5 expression in the forelimb
... for Hox genes in limb development It is well known that Hox genes are required for normal limb ...these genes play in anteroposterior and proximodistal patterning of the developing ...
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DNA methylation and differentiation: HOX genes in muscle cells
... of genes in this region [51]? Although regions of DNA methylation and H3K27me3 sometimes overlap, the relationships between these two epigenetic markers are varied and region-specific ...HOXD genes in Mb ...
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Role of Hox genes in stem cell differentiation
... of Hox genes in their developmental ...autopodal Hox genes HOXA13 and HOXD13 inducing Six2 expression, which is a transcription factor present in developing tendon precursors, even in areas ...
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Common functions of central and posterior Hox genes for the repression of head in the trunk of Drosophila
... Hox genes are localised in complexes, encode conserved homeodomain transcription factors and have mostly been studied for their specialised functions: the formation of distinct structures along the ...
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Duplicated Hox genes in the spider Cupiennius salei
... duplicated Hox genes in ...tional Hox genes are present as two copies that have not be found so far, or that one copy has been lost for the other Hox genes, as has happened to ...
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Limited functions of Hox genes in the larval development of the ascidian Ciona intestinalis
... developmental genes, including Hox genes encoding homeodomain transcription ...Although Hox genes have been regarded to play a key role in the evolution of morphological diversity, as ...
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Hox genes, homeosis and the evolution of segment identity: no need for hopeless monsters
... for Hox gene function, it is not difficult to propose an alternative ...of Hox genes differentially expressed along the A/P axis of the body, and that these control substantial differences between ...
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Expression of Krox-20 and hox genes in hindbrain segments and neural crest
... class Hox genes are both candidates for developmental genes important in hindbrain segmentation ...vertebrate Hox genes are thought to define A-P specification (Akam, 1989; Duboule ...
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Colinearity and non colinearity in the expression of Hox genes in developing chick skin
... 39 Hox genes, organized in four related ...homeotic genes of Drosophila and other animals. Hox genes encode DNA binding transcription factors that regulate their own transcription, the ...
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Dual role for Hox genes and Hox co factors in conferring leg motoneuron survival and identity in Drosophila
... whether Hox genes play a role in diversifying MN identities or circuitries between thoracic ...MNs Hox genes execute both AP patterning and segment- independent ...same Hox gene, ...
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A scientific journey in the garden of the Hox genes: an interview with Jacqueline Deschamps
... the Hox genes? The years 1984-1985 were extremely flourishing for the na- scent field of HOX ...homeotic genes (Lewis, 1978), the homeobox was discovered, almost at the same time by Gehring ...
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Implications of the spatial and temporal regulation of Hox genes on development and evolution
... The Hox code theory initially developed in Drosophila is now used as a paradigm to explain how Hox genes work in other ...the Hox code hypothesis cannot explain but are never discussed in ...
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