Human and Mouse Specific Housekeeping Genes
Tissue-Specific Evolution of Protein Coding Genes in Human and Mouse.
... of genes expressed in testis is also well documented [24,41,74], and could be due to lower purifying selection, an excess of young genes and leaky expression, or to positive selection due to sexual ...in ...
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Translational selection in human: more pronounced in housekeeping genes
... mammalian genes and claims that translational selection in house-keeping genes is stronger that it is in tissue-specific ...of genes do not look convincing at ...for mouse as ...
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Update of the human and mouse Fanconi anemia genes
... the specific role of individual FA protein members and their interaction with non-FA pathways in response to DNA damage are not fully ...in specific organ or cell types. The observation that a ...
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Amplification of a specific set of intracisternal A-particle genes in a mouse plasmacytoma.
... quence probes from the MOPC 104E clones hybridized to restriction fragments in BALB/c and tumor DNAs that were equivalent in size to those found in the cloned genes. These results are co[r] ...
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Mining housekeeping genes with a Naive Bayes classifier
... of human genes: only housekeeping genes present in all three list were accepted in the training set, and only tissue specific genes present in at least two of the tissue ...
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Selection of reference genes in mouse embryos and in differentiating human and mouse ES cells
... reference genes identifying the most stable ones for relative quantification of gene expression during differentiation of human ES cells, as well as in differentiated mouse ES cells and in the ...
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Organization of the Mouse and Human Carbonic Anhydrase II Genes a
... The mouse CA I1 clone, pMCAII, (kindly provided by Dr. Curtis) was isolated from a cDNA library derived from splenic mRNA of an anemic Balb/c mouse.28j46 The nearly full-length 1[r] ...
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Defining housekeeping genes suitable for RNA-seq analysis of the human allograft kidney biopsy tissue
... removing genes with an expression value of zero in all ...most genes are not differentially ...that genes with larger RNA-seq counts have lower variance, and data from both the upper and lower ends ...
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Reduced Susceptibility to Antiseptics Is Conferred by Heterologous Housekeeping Genes
... Human oral metagenomic DNA was extracted from the saliva samples collected from 11 healthy individuals, both males and females, from the Department of Microbial Diseases, UCL Eastman Dental Institute. None of the ...
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A Method of Estimating the Numbers of Human and Mouse Immunoglobulin V-Genes
... A standard triangular table listing the number of nucleotide differences was generated by pairwise comparison of all dis- tinct mouse lambda light chain variable region s[r] ...
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Assessment of orthologous splicing isoforms in human and mouse orthologous genes
... the human caspase 9 gene encodes two alternative products with antagonistic functions: the longer isoform is pro-apoptotic whereas the shorter one, which lacks a functional protease domain due to skipping of four ...
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Housekeeping genes tend to show reduced upstream sequence conservation
... most human genes ...of genes. In particular, it has been observed that the promoters of genes encoding regulatory proteins, such as transcription factors and/or developmental proteins, tend to ...
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Transcriptional regulation of the mouse and human interleukin-5 genes in T-lymphocytes
... is specific for m ethylated and hemimethylated DNA and is used to digest the parental DNA template and to select for the m utation-containing synthesized ...
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Organization, evolution and functions of the human and mouse Ly6/uPAR family genes
... family genes are conserved across species sug- gesting that they are evolutionarily ...the genes in this family in clusters on multiple chromo- somes suggests that both gene duplications and transloca- ...
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Conserved modularity and potential for alternate splicing in mouse and human Slit genes
... Slit genes in human and mouse using long distance PCR and in silico mapping, search for additional members of the vertebrate Slit gene family and search for evidence of alternate splicing of Slit ...
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Exploring the potential relevance of human-specific genes to complex disease
... (human- specific) genes among human disease ...young genes perform functions of sufficient importance to ensure that they have immediately come to clinical attention when ...younger ...
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Sall genes regulate region specific morphogenesis in the mouse limb by modulating Hox activities
... developing mouse limb, we confirm the importance of transcription factors encoded by the Sall gene family in proper limb morphogenesis, and further show that they have overlapping activities in regulating regional ...
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New genes drive the evolution of gene interaction networks in the human and mouse genomes
... new genes originating throughout various stages in the lineages toward human and ...new genes into GGI networks reconstructed with four different data sources in both human and ...new ...
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Validation of housekeeping genes for normalizing RNA expression in real-time PCR
... In order to create maximum vari- ability, we used subjects of different ages, sex, and ethnic backgrounds. We also used different tissues or cell types sampled at different time points, which included cells challenged ...
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Factors affecting synonymous codon usage of housekeeping genes in Drosophila melanogaster
... HTS genes We used ENC and CBI to examine the extent of CUB in ...HTS genes. Differences in CUB between HK and HTS genes were analyzed using the nonparametric Mann-Whitney ...HTS genes. The ...
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