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Human B Lymphocytes

Activation of Ca2+ dependent K+ channels in human B lymphocytes by anti immunoglobulin

Activation of Ca2+ dependent K+ channels in human B lymphocytes by anti immunoglobulin

... external Ca2+ abolished the prolonged hyperpolarization. In fact, a sizable Na+-dependent depolarization was unmasked. This study demonstrates that in human B lymphocytes, Ca2+-dependent K+ channels ...

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Effect of Hepatitis C Virus Core Protein on the Molecular Profiling of Human B Lymphocytes

Effect of Hepatitis C Virus Core Protein on the Molecular Profiling of Human B Lymphocytes

... of B cells, the primary players in the hu- moral immune response, during HCV infection is largely ...on human B cells, we conducted gene expression profiling of serial RNA samples from B cells ...

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First Days in the Life of Naive Human B Lymphocytes Infected with Epstein Barr Virus

First Days in the Life of Naive Human B Lymphocytes Infected with Epstein Barr Virus

... resting human B lympho- cytes, reprograms them, induces their proliferation, and establishes a latent infection in ...EBV-infected B cells in vitro are known, but their functions in the early, ...

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Infection of Human B Lymphocytes with Lymphocryptoviruses Related to Epstein-Barr Virus

Infection of Human B Lymphocytes with Lymphocryptoviruses Related to Epstein-Barr Virus

... between human and nonhuman LCV has been found among the coding sequences for the latent genes, ...for B-cell ...determines B-cell tropism might be closer to latent than lytic gene ...

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Do human B-lymphocytes avoid aging until 60 years?

Do human B-lymphocytes avoid aging until 60 years?

... in human innate and adaptive immunity are associated with advanced ...whole B cell populations from young and early aged healthy donors under 60 ...that B cells avoid the aging program on molecular ...

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Virus Replication and Cytokine Production in Dengue Virus-Infected Human B Lymphocytes

Virus Replication and Cytokine Production in Dengue Virus-Infected Human B Lymphocytes

... RNA isolation and RT-PCR analyses. Total RNA was isolated from cells 1 day after infection with TRI reagent (Sigma, St. Louis, Mo.) according to the man- ufacturer’s protocol. To analyze positive- and negative-stand RNA ...

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Activation of Human B Lymphocytes after Immunization with Pneumococcal Polysaccharides

Activation of Human B Lymphocytes after Immunization with Pneumococcal Polysaccharides

... By 2 wk after immunization, spontaneous anti-PPS antibody production in vitro was no longer detected. Subsequent stimulation of lymphocytes in culture with a wide range of concentrations of specific antigen did ...

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Studies on the Distribution of Surface Immunoglobulins on Human B Lymphocytes

Studies on the Distribution of Surface Immunoglobulins on Human B Lymphocytes

... immunoglobulin antibodies and shown to have a patchy distribution of immunoglobulin on their surfaces that does not form a cap after complexing with antibody. Use of freeze-etch electron microscopy confirmed the ...

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Role of thiamine in Huntington’s disease pathogenesis: In vitro studies

Role of thiamine in Huntington’s disease pathogenesis: In vitro studies

... of human B lymphocytes with CAG ex- panded huntingtin gene and normal cells through the studies on the following items: (1) determination of the supplemented thiamine concentrations that are ef- ...

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Persistent Infection of Epstein-Barr Virus-Positive B Lymphocytes by Human Herpesvirus 8

Persistent Infection of Epstein-Barr Virus-Positive B Lymphocytes by Human Herpesvirus 8

... and B-cell lymphomas (5, 39, 45), as well as in other malignancies and in healthy indi- ...and B lymphocytes (25); however, this did not result in stable virus ...blood B lymphocytes ...

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Human B lymphoma cell line producing B cell growth factor

Human B lymphoma cell line producing B cell growth factor

... a human B cell lymphoma line, produced a factor with a molecular weight of approximately 60,000 which enhanced the proliferation of normal activated human B ...certain B cell ...enhance ...

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Characterization Of Human T-Bet-Expressing B Lymphocytes And Their Role In The Hiv Immune Response

Characterization Of Human T-Bet-Expressing B Lymphocytes And Their Role In The Hiv Immune Response

... and B cell follicles that resembles lymph node structure, and red pulp, a macrophage-rich site that filters the blood ...specific B cell subset termed marginal zone (MZ) B cells, and a perifollicular ...

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Studies of tolerance induction in B lymphocytes

Studies of tolerance induction in B lymphocytes

... for B cell activation. Mature B cells can be polyclonally activated in a non-MHC restricted fashion by preactivated CD4-positive T cells, or membranes prepared from them (Brian et a l , 1988, Noelle et ...

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Glycan Glycan Interaction Determines Shigella Tropism toward Human T Lymphocytes

Glycan Glycan Interaction Determines Shigella Tropism toward Human T Lymphocytes

... Conclusion. Our study brings new insights into how pathogens use glycans to target host cells, especially when they are devoid of particular weapons such as adhesins to trigger strong cell adhesion or bind to a ...

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Interleukin 1 stimulates its own receptor expression on human fibroblasts through the endogenous production of prostaglandin(s)

Interleukin 1 stimulates its own receptor expression on human fibroblasts through the endogenous production of prostaglandin(s)

... The regulation of interleukin 1 receptor (IL 1R) expression on human dermal fibroblasts was investigated. On exposure to IL 1 for 3 h at 37 degrees C, the capacity of fibroblasts to bind 125I-labeled human ...

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CD40-Mediated Induction of CD4 and CXCR4 on B Lymphocytes Correlates with Restricted Susceptibility to Human Immunodeficiency Virus Type 1 Infection: Potential Role of B Lymphocytes as a Viral Reservoir

CD40-Mediated Induction of CD4 and CXCR4 on B Lymphocytes Correlates with Restricted Susceptibility to Human Immunodeficiency Virus Type 1 Infection: Potential Role of B Lymphocytes as a Viral Reservoir

... of B lymphocytes isolated from peripheral blood mono- nuclear ...of B lymphocytes generated in the presence of interleukin-4 and oligomeric soluble CD40L upregulated costimulatory and ...

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Cell-type-specific control elements of the lymphotropic papovavirus enhancer.

Cell-type-specific control elements of the lymphotropic papovavirus enhancer.

... To identify factors that interact with the LPV enhancer, we prepared nuclear extracts from the human cell lines BJA-B, a Burkitt's lymphoma cell line representing mature B lymphocytes 20[r] ...

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Analysis of normal and malignant human B cell growth using gene transfer

Analysis of normal and malignant human B cell growth using gene transfer

... Separated cells were cultured at a concentration of 1 - 2 x 10^ cells/ml RPMI 1640 and incubated at 37®C/5%C02 in a humidified atmosphere. Medium was supplemented with 10% heat-inactivated FCS (Whittaker Bioproducts, ...

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Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

... of B cells was evident in vivo in relation to ...infected B cells based on expression of ORF59 PF-8 directly in archived MACS samples, we found that B cells of KS positives had a higher percentage of ...

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Multicomponent analysis of amino acid transport in human lymphocytes  Diminished L system transport in chronic leukemic B lymphocytes

Multicomponent analysis of amino acid transport in human lymphocytes Diminished L system transport in chronic leukemic B lymphocytes

... in B cell chronic lymphocytic leukemia and compared it with the amino acid transport in isolated B lymphocytes from human blood and ...blood B lymphocytes, which was 1,029 ...

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