Human leukemia cell lines
Cytotoxicity Assessment of Organotin(IV) (2-Metoxyethyl) Methyldithiocarbamate Compounds in Human Leukemia Cell Lines
... the human leukemic promyelocites tested ...HL-60 cell line treated with the same compound demonstrated CD 50 values of lower than ...lymphoblastic leukemia cells, WEHI 7.2, human Chang liver ...
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Molecular Cytotoxic Mechanisms of 1-(3,4,5-Trihydroxyphenyl)-dodecylbenzoate in Human Leukemia Cell Lines
... was added to K562 and Jurkat cells at different concentrations (1-100 µM) and incubated for 24, 48 or 72 h. The same volume of DMSO was added to control wells. MTT solution was added to each well (10% v/v) and the plates ...
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THERAPEUTIC AND BIOLOGICAL ACTIVITIES OF DAPHNE MUCRONATA- A REVIEW Ali Esmail Al-SnafiDOWNLOAD/VIEW
... activated human platelets to the cultured monocytes or HL-60 cells was investigated under the effect of Daphne mucronata extract ...activated human platelets to the plant treated HL-60 cells was also ...
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A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells
... There is evidence for the synergistic effect of combined DNA damaging agents and HDAC inhibitors on cancer cells. However, traditional combination therapy of two individual drugs may possess disadvantages, including ...
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Nanoparticles Induce Oxidative Stress in HT-29 Colon Adenocarcinoma Cell Line After 24 and 48 Hour Exposure
... HepG2 human liver cells and that the toxicity of silver nanomolecules does not change regardless of their size ...in human monocytic leukemia cell lines by ROS mechanism, but not ...
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Upregulation of Human T-Cell Leukemia Virus Type 1 Antisense Transcription by the Viral Tax Protein
... virion-producing cell lines MT-2 and C91/PL, while MJ cells, which produce less viral particles (unpublished data), showed lower luciferase ...evaluated. Cell extract preparation and Western blot ...
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Human T-Cell Leukemia Virus Type 1 Envelope-Mediated Syncytium Formation Can Be Activated in Resistant Mammalian Cell Lines by a Carboxy-Terminal Truncation of the Envelope Cytoplasmic Domain
... vector, and 4 g of either an HTLV Env-derived expression vector (H, HdC8, HdC16, or H⌬C) or a control vector (Mock). The different HTLV Env TM mutants are diagrammed in Fig. 2. Cell extracts were immunoblotted ...
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In vitro infection of primary and retrovirus-infected human leukocytes by human foamy virus.
... of human foamy virus (HFV) was examined in primary and cultured human ...leukocytes. Cell-free infectious viral stocks of HFV were prepared from the human kidney cell line 293 ...
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Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines
... the leukemia cell lineage (lymphoid ...the cell lines from the same lineage. We have shown that myeloid cell lines (K562 and KG-1a) were particularly resistant even to the most ...
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Characterization of Pichinde virus infection of cells of the monocytic lineage.
... To establish a model of monocytic infection by Pichinde virus, we screened human peripheral blood monocytes PBM and two human cell lines, the promonocytic leukemia cell line THP-1 37 and[r] ...
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Expression of c-myc is not critical for cell proliferation in established human leukemia lines
... in cell cycle control, while overexpression can con- tribute to malignant transformation or result in induction of programmed cell death [for detailed reviews see ...the cell cycle ...the ...
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Development and Characterization of Tool Compounds Targeting the Runt Domain’s interaction With Cbfβ
... myeloid leukemia (AML) cell lines, and reduced the progenitor activity of mouse and human leukemia cells harboring the t(8;21), but not normal bone marrow ...and human T ...
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Terpenes from soft corals of the genus Lobophytum (Alcyoniidae): Chemistry and biological activities
... agains human lung adenocarcinoma A-549 and human promyelocytic leukemia HL-60 tumor cell lines, but did not show activity at a concentration of 20 ...
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In Vivo Genomic Footprinting of the Human T-Cell Leukemia Virus Type 1 (HTLV-1) Long Terminal Repeat Enhancer Sequences in HTLV-1-Infected Human T-Cell Lines with Different Levels of Tax I Activity
... HTLV-1-infected cell lines MT-2 and ...appropriate cell line, treated with DMS in vitro, cleaved with piperidine, and processed in parallel with the in vivo ...
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Inhibition of constitutively active Jak Stat pathway suppresses cell growth of human T cell leukemia virus type 1 infected T cell lines and primary adult T cell leukemia cells
... We also examined the effects of AG490 on the expression of IAP and Bcl-2 family members, which determine the response to apoptotic stimuli. AG490 significantly altered the expression of XIAP and survivin, which are ...
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Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis
... 81 leukemia cell lines were downloaded from the Cancer Genomics Hub (cghub, ...for human leu- kemia cell lines (JURKAT, ALL-SIL, DND41, and K562), total mRNA was isolated with ...
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Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype
... Neither cell growth nor Erk/Akt activity was affected in uninfected H9 cells upon transfection of Nox5␣ siRNAs (data not ...T-cell lines and ATL ...
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Role of HTLV 1 orf I encoded proteins in viral transmission and persistence
... HTLV: human T‑cell leukemia virus; ICAM: intercellular adhesion molecule; IL‑2: interleukin‑2; IL‑2R: interleukin‑2 receptor; JAK‑STAT : Janus‑associated kinase and signal transducer and activator of ...
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Selective infection of human T-lymphotropic virus type 1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses containing HTLV-1 tax response elements in the long terminal repeat.
... the human immunodeficiency virus long terminal repeat (HIV LTR) enhancer/promoter sequences contribute to the replication ability of HIV in different T-cell lines; mutation of these sequences can ...
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Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells.
... Cell tropism of SRV-1a Cell group tested HUT78 human T helper cell line from sezary leukemia H9 human T-cell line K-562 human chronic myelogenous leukemia cell line Raji human Burkitt's [r] ...
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