Hydrophobic Region
Role of N-Terminal Hydrophobic Region in Modulating the Subcellular Localization and Enzyme Activity of the Bisphosphate Nucleotidase from Debaryomyces hansenii
... N-terminal hydrophobic region is essential for the mem- brane localization of ...minal region (Fig. 2A). However, the functional importance of this region has not been ...this region is ...
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The first hydrophobic region of the HPV16 E5 protein determines protein cellular location and facilitates anchorage independent growth
... first hydrophobic region results in loss of colocalisation with the ER, early endosomes and ...first hydrophobic region results in loss of growth in soft ...first hydrophobic ...
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Effects of deletions in the carboxy-terminal hydrophobic region of herpes simplex virus glycoprotein gB on intracellular transport and membrane anchoring.
... Thus, although these mutants are defective in intracellular transport to the Golgi complex or the cell surface, they form dimers and are transported to the nuclear envelope in a manner s[r] ...
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Consensus analysis of Signal Peptide Peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared to Presenilins
... first hydrophobic region, plus the downstream 100 residues ...first hydrophobic region of SPPL2a, -2b, and -2c, and consensus sites for N-glycosylation within the downstream 100 ...
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Functional Analysis of Subunit e of the F1Fo-ATP Synthase of the Yeast Saccharomyces cerevisiae: Importance of the N-Terminal Membrane Anchor Region
... a hydrophobic region located at its N-terminal ...C-terminal region of Su e resides in the intermembrane space and contains a conserved coiled-coil ...N-terminal hydrophobic region ...
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Hemagglutinin-neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor.
... The deduced amino acid sequence indicated that the only major hydrophobic region in the protein sufficiently long to anchor the protein in the membrane is located near the N terminus ami[r] ...
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A glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase.
... Coprecipitation of E5-16K protein complex and E5 dimer formation in cells expressing E5 epitope proteins containing amino acid substitutions within the middle hydrophobic region.. A Extr[r] ...
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Insight into the mechanism of polyphenols on the activity of HMGR by molecular docking
... The findings of the present docking study demonstrate that all the polyphenols tested in this study can bind in the hydrophobic region of the L-domain and cis-loop, leading to [r] ...
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Trafficking of bdelloid rotifer late embryogenesis abundant proteins
... N-terminal hydrophobic region and a C-terminal sequence ATEL that resembles endoplasmic reticulum (ER) retention signals like KDEL and HDEL (Munro and Pelham, 1987; Pelham, 1990), suggesting that ArLEA1A ...
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Regulated processing of hepatitis C virus core protein is linked to subcellular localization.
... bic region has been demonstrated to be associated with the endoplasmic reticulum membrane ...the hydrophobic region between residues 174 and 191 may function as an an- chor to facilitate cytoplasmic ...
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Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations.
... Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53.. The replication functions of SV40 T antig[r] ...
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The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins.
... central region of ...central region but also a certain region(s) of the NS3 serine proteinase (in the form of the NS3-NS4A ...central region and uses its N- and/or C-terminal segments to ...
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Common and unique features of T antigens encoded by the polyomavirus group.
... Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53.. Mutations near the carboxyl terminus of t[r] ...
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The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C
... the hydrophobic region does not traverse membranes, demonstrating that both the N-terminal and C-terminal halves of the LITAF domain reside on the cytosolic sur- face of membranes, in agreement with an ...
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The intrinsically disordered Tarp protein from chlamydia binds actin with a partially preformed helix
... sequential region, homologous to other WH2 domains, is alone sufficient to interact with ...actin hydrophobic cleft (‘+’ barbed-end) whilst a number of extended residues, contiguous to the helix, facilitate ...
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Nucleotide Sequence of the Akv env Gene
... This cleavage generates a region of 42 uncharged, relatively hydrophobic amino acids at the amino terminus of p1SE, which is located in a position analogous to the hydrophobic membrane f[r] ...
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Critical Role of Conserved Hydrophobic Residues within the Major Homology Region in Mature Retroviral Capsid Assembly
... conserved hydrophobic residues, have a critical role in the assembly of the mature capsid shell that is independent of any additional Gag function(s) they may ...
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Preparation of Hydrophobic Nylon Fabric
... Hydrophobic nylon fabric was chemically treated using BTCA, TBT and OA. Experimental results showed that the BTCA treatment increased reactive sites in nylon, the TBT treatment increased the surface roughness of ...
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Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
... a hydrophobic PCL chain and a hydrophilic PEG chain, ...The hydrophobic drug could then be encap- sulated into a hydrophobic core by means of the hydrophobic interaction of PCL and CUR and, ...
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Low pH-Induced Conformational Change in Herpes Simplex Virus Glycoprotein B
... lost in virions exposed to pH 5.9. Similar results were obtained with an additional MAb to domain I, SS55 (Fig. 1; Table 1). This suggests a specific change in the antigenic structure of the fusion domain. As a control, ...
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