II class II major histocompatibility complex
Efficient Class II Major Histocompatibility Complex Presentation of Endogenously Synthesized Hepatitis C Virus Core Protein by Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Lines to CD4+ T Cells
... Hepatitis C virus (HCV) has been known as a major etio- logic agent of posttransfusion and sporadic community-ac- quired non-A, non-B hepatitis. Like the other members in the family Flaviviridae, HCV contains a ...
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Genomic organisation and transcript identification in the class II region of the human major histocompatibility complex
... and class II expression, were transfected with varying length constructs of li and labelled with rabbit anti-Ii antibody (Bakke and Dobberstein, ...directs class Il/Ii complexes to ...
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Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice.
... Second, this study examined the role of the class II-restricted immune response in demyelinating disease. Although the pre- cise mechanism of TMEV-induced demyelination has not been determined, several ...
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Cytotoxic T-Lymphocyte Precursor Frequencies in BALB/c Mice after Acute Respiratory Syncytial Virus (RSV) Infection or Immunization with a Formalin-Inactivated RSV Vaccine
... study, major histocompatibility complex (MHC) class I- and II-restricted, RSV-specific cytotoxic T-lymphocyte precursor (CTLp) frequencies were determined in bronchoalveolar lavage ...
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Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... HLA class II downregulation in context. The gene products mentioned may represent just the tip of the iceberg that con- stitutes the array of herpesvirus gene products with significant effects on the immune ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), MHC molecules also ...
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CD200 fusion protein decreases microglial activation in the hippocampus of aged rats
... including major histocompatibility complex Class II (MHCII) and CD40 mRNA, as well as MHCII immunoreactivity, were increased in hippocampus of aged, compared with young, rats and that ...
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Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability
... The major histocompatibility complex (MHC) represents a multigene family that is known to display allelic and gene copy number variations. Primate species such as humans, chimpanzees (Pan ...
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Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins.
... Ig class switching and alter cytokine- related susceptibility patterns in parasitic and viral infections (14, 30, ...no major switch to the production of Th2 ...
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Roles of Major Histocompatibility Complex Class II in Inducing Protective Immune Responses to Influenza Vaccination
... The roles of MHC-II molecule have been investigated in the context of infection models, relating to the study of CD4 ⫹ T cells for controlling pathogens. MHC-II molecules were required for the development, ...
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T-cell recognition in experimental autoimmune thyroiditis
... four major hormonogenic sites in Tg, we demonstrated that both CH9 and ADA2 recognize an epitope containing the T4 at position 2553 in human ...by major histocompatibility complex class ...
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T-Cell Vaccination Alters the Course of Murine Herpesvirus 68 Infection and the Establishment of Viral Latency in Mice
... a major health concern, and there is significant interest in developing vaccines against this class of viral ...for class I- and class II-restricted epitopes on the acute phase of the ...
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A defect in the regulation of major histocompatibility complex class II gene expression in human HLA DR negative lymphocytes from patients with combined immunodeficiency syndrome
... Patients with an autosomal recessive combined immunodeficiency are characterized by an HLA negative phenotype of activated T and B lymphocytes. To determine the molecular basis of this syndrome we have studied the ...
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Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... of major histocompatibility complex (MHC) class II (HLA-DR) on atypical and malignant primary mammary epithelial cells, as well as the magnitude of the stromal T lymphocytes (T4 subset) ...
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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes
... encode major histocompatibility complex (MHC)-related proteins, 2 to encode MHC class I homologues, and 3 to encode MHC class II homologues; 4 encode the homologues of C-type ...
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Phenotypic changes in Langerhans' cells after infection with arboviruses: a role in the immune response to epidermally acquired viral infection?
... of major histocompatibility complex class I and II antigens (4, 22, 25) and the accessory and costimulatory molecules intra- cellular adhesion molecule-1–CD54, CD11a, CD18 (6, 21), and ...
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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... MHC class I is inhibited by KSHV proteins vIRF-1 (23) and K3/K5 (19) by either down- regulation or degradation of MHC I molecules, ...MHC II presentation by viruses was observed or at least reported far ...
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Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency
... RFX complex [12] which allow, together with CIITA [7,13,14], CMH class II gene ...CMH class II molecules surface expression on antigen-presenting cells is behind impaired immune ...
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<p>Major histocompatibility complex class II molecule in non-small cell lung cancer diagnosis, prognosis and treatment</p>
... MHC class II also has been studied in ...MHC class II had been ...MHC class II could be induced by IFN- γ in TKB-3 and TKB-4 cell lines and the induced MHC class II ...
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Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment
... MHC II + cells in the CC contralateral to the ischemic hemisphere (Figure ...MHC II + cells in rats treated with levodopa/ benserazide (399 ± 66 cells, saline treatment 216 ± 45 cells, Figure ...MHC ...
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