Inclusion Complex (IC)
Exploring Existence of Host-Guest Inclusion Complex of β-Cyclodextrin of a Biologically Active Compound with the Manifestation of Diverse Interactions
... p-nitro benzaldehyde (PNB) is a very useful compound in organic synthesis. It also has applications in medicinal chemistry. (Scheme2). In this present work we attempt to ascertain the formation and nature of ...
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Tissue Engineering Scaffolds with Enhanced Oxygen Delivery Using a Cyclodextrin Inclusion Complex
... the inclusion of the guest molecules in the CD cavity hinders their molecular vibrations, and therefore the intensity of their absorption bands is ...an inclusion complex with this specific guest due ...
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Preparation and Characterization of Thalidomide Hyroxy Propyl -Cyclodextrin Inclusion Complex
... and SEM studies confirmed the formation of inclusion complex. The apparent solubility constant value obtained from phase solubility study is an evidance for the increased solubility rate. These techniques ...
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Binding of the Inclusion Complex of Atorvastatin-β-cyclodextrin to Bovine Serum Albumin
... The objective of the paper is to determine the effect of β-cyclodextrin complexation on the interaction of the popular drug, Atorvastatin to bovine serum albumin. Fluorescence and 2D Rotating-frame Overhauser effect ...
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FORMULATION AND EVALUATION OF TOPICAL HERBAL GEL CONTAINING INCLUSION COMPLEX OF CURCUMIN:
... The inclusion complex with high aqueous solubility was loaded in the topical gel containing (2% CUR) which was prepared using carbopol, sodium CMC, and guar gum and evaluated for viscosity, spreadability, ...
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EVALUATION OF DIURETIC ACTIVITY OF HYDROCHLOROTHIAZIDE ? CYCLODEXTRIN INCLUSION COMPLEX IN WISTAR RATS
... HCT-γCD complex has statistically significant high Na + excretion (p< ...the inclusion complex and the control but were not statistically significant (p > ...
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Characterization, activity, and computer modeling of a molecular inclusion complex containing rifaldazine
... a complex manufacturing process, and uncertain ...molecular inclusion complex refers to a complex com- pound or an unbonded association in which a guest molecule (usually a low molecular ...
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Spectroscopic Study of Inclusion Complex of the Ethidium Bromide with -Cyclodextrin in Solution NMR
... host inclusion complex was formed between β-cyclodextrin and Ethidium ...the inclusion complex was in the ratio of 1:1 as obtained from Scott’s ...host-guest inclusion was further clear ...
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Solid state characterization of domperidone: Hydroxypropyl-?-cyclodextrin inclusion complex
... The percent drug content of each inclusion complex was determined using powder equivalent to 10 mg DPD and was dissolved in 20 ml 0.1M HCl using the mechanical shaker for 20 min. and to the solution ...
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Enhancing the Solubility and Dissolution Rate of Meclizine Hydrochloride by Inclusion Complex
... the inclusion complexation technique and inclusion complex based fast dissolving tablets of Meclizine HCl would provide quick-onset of ...using Inclusion complex in 1:2 ratio by ...
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CYCLODEXTRIN INCLUSION COMPLEX TO ENHANCE SOLUBILITY OF POORLY WATER SOLUBLE DRUGS: A REVIEW
... Low solubility compounds show dissolution rate limited absorption and hence poor absorption, distribution and target organ delivery. Improvement of aqueous solubility in such a case is valuable goal to improve ...
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“ENHANCEMENT OF REPAGLINIDE AQUEOUS SOLUBILITY BY INCLUSION COMPLEX FORMATION WITH CYCLODEXTRINS AND SYNERGISTIC EFFECT OF BASIC pH AND CO-SOLVENT” by Deshmukh Mohammad Rehan, Shaikh Mohammad Sameer, India.
... by inclusion complex. Repaglinide forms stable inclusion complex with HP β-CD in solid form by kneading ...So inclusion complexation with HP β- CD combined with basic pH and co-solvent, ...
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Matrix Tablet Containing Quaternary Inclusion Complex of Domperidone for Treatment of Diabetic Gastroparesis
... Objective: The present investigation is aimed at development and optimization of a pH independent controlled release matrix tablet containing mannitol based quaternary inclusion complex (QIC) of domperidone ...
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Comparative Evaluation of Inclusion Complex of Aceclofenac Prepared by different Techniques.
... choose. Inclusion complex with β-cyclodextrins is the most attractive technique to enhance aqueous solubility of poorly soluble ...cyclodextrins inclusion c ...
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Per(3 deoxy) α cyclomannin: an n butanol hexahydrate inclusion complex
... With the per(3-deoxy)--cyclomannin-n-butanol hexa- hydrate inclusion complex, (I), we describe the ®rst inclusion compound of a non-glucose cyclooligosaccharide. Similar to -cyclomannin ...
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Fast Dissolving Oral Film of Piroxicam: Solubility Enhancement by forming an Inclusion Complex with β-cyclodextrin, Formulation and Evaluation
... IC2, i.e., the inclusion complex of piroxicam with β-CD (1:1 ratio) prepared by the kneading method showed a faster dissolution rate (Figure 2). Therefore for the formulation of fast dissolving films ...
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Preparation of a Menthol/beta-Cyclodextrin Inclusion Complex Using Supercritical CO2
... In the work, there was a maximum inclusion yield of 93.75 %. SEM, DSC and XRD data all confirmed the formation of an inclusion complex between menthol and β-CD. These results provided evidence that ...
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HYDROXYPROPYL β -CYCLODEXTRIN INCLUSION COMPLEX OF CURCUMIN USING FLUORESCENCE LIFETIME MEASUREMENT.
... Although safe in most cases, ancient treatments are ignored neither their active components nor their molecular targets are well defined. This is not the case, however, with curcumin, a yellow pigment substance and ...
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Study of VD3 β Clodextrin Inclusion Complex
... biologically active form of vitamin D. Calcitriol circulates as a hormone in the blood, regulating the concentra- tion of calcium and phosphate in the bloodstream and promoting the healthy growth and remodeling of bone. ...
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Controlled Release Profile of Imidacloprid-β-Cyclodextrin Inclusion Complex Embedded Polypropylene Filament Yarns
... (IMI-β-CD) inclusion complex was synthesized and effectively incorporated into filament yarns of ...IMI-β-CD inclusion complex were determined by Fourier transform infrared spectroscopy, ...
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