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Integration site

Mouse Mammary Tumor Virus Integration Site Selection in Human and Mouse Genomes

Mouse Mammary Tumor Virus Integration Site Selection in Human and Mouse Genomes

... on integration site preferences, retroviruses can be placed into three ...MMTV integration profile to those of other ...MMTV integration site selection in human and mouse ...no ...

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Viral Determinants of Integration Site Preferences of Simian Immunodeficiency Virus-Based Vectors

Viral Determinants of Integration Site Preferences of Simian Immunodeficiency Virus-Based Vectors

... (SIV) integration sites in a chronically SIV-infected human T-cell line and in periph- eral blood mononuclear cells derived from rhesus monkey bone marrow stem cells transduced with an SIV-based vector were also ...

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Overexpression of ecotropic viral integration site-1 is a prognostic factor of lung squamous cell cancer

Overexpression of ecotropic viral integration site-1 is a prognostic factor of lung squamous cell cancer

... Keywords: ecotropic viral integration site-1, lung squamous cell cancer, biomarker, prognosis, immunohistochemistry, overall survival rate.. Introduction.[r] ...

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Lentiviral Integration Site Targeting: Host Determinants and Consequences

Lentiviral Integration Site Targeting: Host Determinants and Consequences

... the integration of donor into target DNA [1-3], and the reaction shows weak specificity for target sequence ...Furthermore, integration occurs in a non- random distribution in the host genome, which is not ...

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HIV latency and integration site placement in five cell based models

HIV latency and integration site placement in five cell based models

... of integration site associated with latency, we generated a set of inducible and expressed integration sites using a primary central memory CD4 + T cell model of latency [28,29], collected four ...

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Frequent site-specific deletion of coliphage lambda murine sarcoma virus recombinants and its use in the identification of a retrovirus integration site.

Frequent site-specific deletion of coliphage lambda murine sarcoma virus recombinants and its use in the identification of a retrovirus integration site.

... 488-497 0022-538X/80/08-0488/10$02.00/0 Frequent Site-Specific Deletion of Coliphage X Murine Sarcoma Virus Recombinants and Its Use in the Identification of a Retrovirus Integration Sit[r] ...

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Variations in integration site of avian oncornaviruses in different hosts.

Variations in integration site of avian oncornaviruses in different hosts.

... The reassociation pattern of denatured fragments that contain proviral DNA from duck cells infected with either an avian sarcoma virus or an avian leukosis virus indicates that the viral[r] ...

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Transcriptional Analysis of the Adeno-Associated Virus Integration Site

Transcriptional Analysis of the Adeno-Associated Virus Integration Site

... integrate site specifically into a ubiquitously transcribed region raises several questions with regard to the nonpathogenic character of ...for site-specific integration, Henckaerts et ...that ...

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Analysis of Wild-Type and Mutant SL3-3 Murine Leukemia Virus Insertions in the c-myc Promoter during Lymphomagenesis Reveals Target Site Hot Spots, Virus-Dependent Patterns, and Frequent Error-Prone Gap Repair

Analysis of Wild-Type and Mutant SL3-3 Murine Leukemia Virus Insertions in the c-myc Promoter during Lymphomagenesis Reveals Target Site Hot Spots, Virus-Dependent Patterns, and Frequent Error-Prone Gap Repair

... indicated integration sites specify the upstream positions relative to transcription start site ( ⫹ 1) at exon 1 (c-myc promoter ...eral integration site hot spots where up to nine proviruses ...

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A High-Throughput Method for Cloning and Sequencing Human Immunodeficiency Virus Type 1 Integration Sites

A High-Throughput Method for Cloning and Sequencing Human Immunodeficiency Virus Type 1 Integration Sites

... for integration exist. The mechanism that determines target site specificity is not well ...of integration, studies analyzing the mechanism and factors that control target site selection ...

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Relationship between Retroviral DNA Integration and Gene Expression

Relationship between Retroviral DNA Integration and Gene Expression

... as integration targets (5, ...target site selection for certain regions of the chromosome, such as those that are transcriptionally active (31) or those associated with other fea- tures, such as DNase I ...

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Adeno-Associated Virus Site-Specific Integration Is Regulated by TRP-185

Adeno-Associated Virus Site-Specific Integration Is Regulated by TRP-185

... AAV integration site determination? From an evolutionary perspective, there is no evidence for AAV site-specific integra- tion in ...AAV site-specific integration specifically in ...

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Integration of hepatitis B virus: analysis of unoccupied sites.

Integration of hepatitis B virus: analysis of unoccupied sites.

... In NHAL14, the unoccupied site of AL-14, sequences about 240 bases downstream from the left-end integration site were found to be highly homologous to the polymorphic region of the human[r] ...

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Combining Comprehensive Analysis of Off Site Lambda Phage Integration with a CRISPR Based Means of Characterizing Downstream Physiology

Combining Comprehensive Analysis of Off Site Lambda Phage Integration with a CRISPR Based Means of Characterizing Downstream Physiology

... detected integration sites. On the outer ring, the positions of integration sites are ...the site was found in 1 (black), 2 to 4 (green), or ⬎ 4 (red) replicate ...each integration site ...

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Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors

Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors

... insertion site loci identified in the mutant by integration site PCR; IS, integration sites shared by these clones were verified by site-specific PCR; ?, vector copy number was not ...

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A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome

A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome

... single-copy integration system that enables the cloning vector to integrate at a specific engineered site, within an untranscribed intergenic region, in the chromosome of Staphylococcus ...L54a ...

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The site-specific integration reaction of Listeria phage A118 integrase, a serine recombinase

The site-specific integration reaction of Listeria phage A118 integrase, a serine recombinase

... the site se- lectivity for ...ite site-selectivity for recombination [24,26,27,33] and have been found to require recombination directionality factors or Xis-like proteins for attL×attR recombination ...

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CozE is a member of the MreCD complex that directs cell elongation in Streptococcus pneumoniae

CozE is a member of the MreCD complex that directs cell elongation in Streptococcus pneumoniae

... insertion site used by the original Mariner transposon in the ...TA site was identified was scored and used to generate a read count profile across all TA sites in the ...

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The genomic instability associated with integrated simian virus 40 DNA is dependent on the origin of replication and early control region.

The genomic instability associated with integrated simian virus 40 DNA is dependent on the origin of replication and early control region.

... The presence of the SV40 control region, including the origin, enhancer, and promoter sequences, was sufficient to cause genomic instability at the site of integration of pSV2neo in five[r] ...

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Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus

Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus

... is site-specific recombination, normally at the chromo- somal attB site via Mx8 att, developed from myxophage Mx8 DNA [15, ...or site-directed insertion ...and integration elements, ...

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