Itopride Hydrochloride
FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLETS OF ITOPRIDE HYDROCHLORIDE
... short biological half-life (6 h), 60 % bioavailability and dosage frequency more than once a day (50 mg t.i.d.) make the Itopride Hydrochloride an ideal candidate for the controlled drug delivery systems. ...
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FORMULATION DEVELOPMENT AND CHARACTERIZATION OF SUPERPOROUS HYDROGEL OF ITOPRIDE HYDROCHLORIDE FOR GASTRORETENTIVE DRUG DELIVERY SYSTEM
... Superporous hydrogel composites were synthesized by preparing 50% acrylamide solution (AM) and 50% acrylic acid solution (AA) as a monomer, 2.5% N,N’-methylene bisacrylamide (BIS) as a cross linker, 20% Ammonium ...
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A Pharmaceutical Study on Different Approaches for Itopride Hydrochloride Sustainment: In vitro and in vivo evaluation
... Recent trends indicate that dosage form drug delivery systems are especially suitable for achieving sustained or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain ...
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CONTROLLED RELEASE LAYERED MATRIX TABLETS OF ITOPRIDE HYDROCHLORIDE: IN VITRO AND IN VIVO EVALUATION
... Itopride hydrochloride and nimesulide were gift samples from Sun Pharmaceuticals and Alembic limited, Vadodara India. Polyethylene oxide WSR 303 (Polyox) was purchased from HiMedia, Mumbai. Polyvinyl ...
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DEVELOPMENT AND OPTIMIZATION OF ITOPRIDE HYDROCHLORIDE FAST DISINTEGRATING TABLETS USING FACTORIAL DESIGN AND RESPONSE SURFACE METHODOLOGY
... ABSTRACT: The objective of this work was to use a full factorial design and response surface methodology to optimize and prepare fast disintegrating tablets of Itopride hydrochloride (ITOHCl). Tablets were ...
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Method develpopment and validation of Itopride Hydrochloride and Rabeprazple Sodium in pharmaceutical dosage form by Reversed Phase High Performance Liquid Chromatography
... Itopride hydrochloride is a benzamide derivative in the class of prokinetic drugs ...for itopride hydrochloride and rabeprazole sodium was developed and validated the ...
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SIMULTANEOUS ESTIMATION OF ESOMEPRAZOLE MAGNESIUM TRIHYDRATE, ITOPRIDE HYDROCHLORIDE AND MOSAPRIDE CITRATE BY RP HPLC METHOD: OPTIMIZATION, DEVELOPMENT, VALIDATION AND APPLICATION TO LABORATORY SAMPLE
... Itopride hydrochloride (ITO) is chemically known as N-[[4-(2-dimethyaminoethoxy)phenyl]methyl]- 3,4-dimethoxybenzamide hydrochloride) [Figure 1(b)], it inhibits dopamine and has a gastrokinetic ...
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A NOVEL VALIDATED RP-HPLC METHOD FOR THE DETERMINATION OF ITOPRIDE HYDROCHLORIDE IN BULK AND PHARMACEUTICAL TABLET DOSAGE FORMS
... for Itopride HCl. The retention time for Itopride HCl was ...of Itopride HCl showed that the drug absorbed maximum at 235 nm, so this wavelength was selected as the detection ...for Itopride ...
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Design and in vitro/in vivo evaluation of sustained-release floating tablets of itopride hydrochloride
... ITO hydrochloride (HCl) were prepared by direct compression using different hydrocolloid polymers such as hydroxypropyl methylcellulose and ethylcellulose and/or methacrylic acid polymers Eudragit RSPM and ...
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Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro
... Because itopride enhanced only contractions induced by ACh and failed to increase spontaneous or stimulation-induced ACh release, they concluded that itopride stimulates ileal activity by prevention of ACh ...
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FORMULATION & EVALUATION OF ITOPRIDE HCL SUSTAINED RELEASE PELLETS P
... . Itopride hydrochloride is an oral prokinetic agent used in the treatment of gastric motility disorders like dyspepsia of a non- ulcer/dysmotility type 8-9 ...that Itopride may have prokinetic ...
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FORMULATION AND DEVELOPMENT OF FLOATING DRUG DELIVERY OF ITOPRIDE HCL
... beyond this. The bioavailability can be improved by making the drug completely absorbed in the stomach and upper part of the small intestine. It has a half life of 6hrs. The short half life of Itopride ...
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Volume 4 | Issue 2 - 2014
... trihydrate, itopride hydrochloride and mosapride citrate by RP- HPLC method: optimization, development, validation and application to laboratory sample, International Journal of Pharmaceutical Sciences and ...
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A NOVEL APPROACH FOR FORMULATION OF ITOPRIDE HCL MUPS SUSTAINED RELEASE TABLET
... Pellets containing Itopride Hydrochloride were prepared using the multifunction fluid bed coater, which is able to process pellets as well as micro granules. Spheres consisting Celesphere 203, with mean ...
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Efficacy of Itopride in the Prevention of Lubiprostone Induced Nausea
... of itopride hydrochloride (50 mg tablet twice a day before meals) together with lubiprostone to prevent ...and itopride (itopride group; n = ...
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Design and Development of Hydrodynamically Balanced Tablet of Itopride
... polymers. Different batches of matrix tablets of itopride were prepared using various drugs to polymer ratio by direct compression method. The compressed tablets were evaluated for physical characteristics, drug ...
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Colorimetric determination of Ziprasidone hydrochloride in pharmaceutical formulations
... ziprasidone hydrochloride in its pharmaceutical formulations are added to a fixed amount of ziprasidone hydrochloride (10 µg/ml) solution and the absorbance measurements are carried out under optimal ...
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SIMULTANEOUS QUANTITATION AND VALIDATION OF PHENYLEPHRINE HYDRO CHLORIDE, AMBROXOL HYDROCHLORIDE AND LEVOCITRIZINE HYDROCHLORIDE IN SYRUP FORMULATION BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
... INTRODUCTION: The chemical name of Phenylephrine hydrochloride is (R)-(α)-m- Hydroxy-α-[(methyl amino) methyl] benzyl alcohol hydrochloride. The structure of Phenylephrine hydrochloride is given in ...
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SPECTROPHOTOMETRIC DETERMINATION OF CINACALCET HYDROCHLORIDE IN BULK
... REVIEW OF CINACALCET HYDROCHLORIDE Al-Hilali N et al, (2011), cinacalcet has markedly improved the management of hyperparathyroidism in patients on hemodialysis. However, to the best of our knowledge, there are no ...
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Itopride: a prokinetic agent with dual mode of action and positive safety profile for the management of upper gastrointestinal dysmotility disorders
... agents. Itopride is indicated in adult patients with functional dyspepsia, in patients with dyspeptic ...of itopride is connected with its dual effect, consisting in influencing the levels of the enzyme ...
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