laser mass-spectrometry technique
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... Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was recently evaluated as a useful tool for the rapid identification of a variety of ...identification ...
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Novel laser spectroscopic technique for continuous analysis of N2O isotopomers - application and intercomparison with isotope ratio mass spectrometry
... The laser spectrometer consisted of a single-mode, pulsed QCL (Alpes Lasers SA, Neuchâtel, Switzerland) emitting at 2188 cm –1 , a multipass absorption cell (AMAC-56; optical path length 56 m, volume 500 mL; ...
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Fundamental Studies of Femtosecond Laser Interactions with Solids and Their Applications to Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Environmental Analysis
... Solution-based (SO) Inductively coupled plasma mass spectrometry (ICP- MS) has gained wide acceptance in elemental and isotopic analysis of a wide range of matrices [1-8] . Capability of multi-element ...
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Advances in Identification of Clinical Yeast Isolates by Use of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) is a soft ionization technique that generates a protein-based spectral profile or “fingerprint” that ...
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Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS)
... the laser-based tissue microdissection ...detection technique. Gel-based techni- ques do not meet this requirement but mass spectrome- try by MALDI (matrix assisted laser desorption and ...
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Identification of Highly Pathogenic Microorganisms by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: Results of an Interlaboratory Ring Trial
... MALDI-TOF mass spectrometry is a rapid, accurate, and relatively inexpensive technique that is becoming increasingly impor- tant in microbiological diagnostics to complement classical microbiology, ...
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Creation of an In House Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Corynebacterineae Database Overcomes Difficulties in Identification of Nocardia farcinica Clinical Isolates
... Matrix-assisted laser desorption ioniza- tion–time of flight (MALDI-TOF) mass spectrometry is a relatively novel technique used for identification of ...
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Identification of Rare Pathogenic Bacteria in a Clinical Microbiology Laboratory: Impact of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
... matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry (MS) has become a powerful tool for routine identification in many clinical ...molecular technique for ...
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Implementation of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry in Routine Clinical Laboratories Improves Identification of Coagulase Negative Staphylococci and Reveals the Pathogenic Role of Staphylococcus lugdunensis
... the technique was labor-intensive and uncommon CoNS were usually not identified (5, ...trix-assisted laser desorption ionization–time of flight mass spec- trometry (MALDI-TOF MS) has emerged as a ...
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Mass determination of major plasma proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
... Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI- TOF/MS), invented in the late 1980s (1,2), serves as a technique for analyzing peptides and proteins in ...
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Matrix assisted ultraviolet laser desorption/ionisation mass spectrometry of macromolecules
... Oligonucleotides (both single-stranded and double-stranded ) and ribonucleic acid have been analysed. O ligonucleotides up to 34-mers (pd(T) 34 ), i.e. relative m olecular mass >10 000, have been detected121. ...
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Evaluation of the Andromas Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry System for Identification of Aerobically Growing Gram Positive Bacilli
... Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) is a rapid bacterial identification technique that is increasingly used in microbiology laboratories ...
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Exploring femtosecond laser ablation in single-particle aerosol mass spectrometry
... excimer laser is 20 cm from the lens, and ionization happens 3–4 cm after the focus position for F2 and ...detection laser, whereas for the experiments with the fs laser we had to apply a differ- ent ...
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Extraction and Direct Quantification of Salicylic Acid in Arabidopsis Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
... non-ablative laser desorption ...matrix-assisted laser desorption/ionization (MALDI)-MS thermal excitation is fundamentally constrained by the matrix properties, such as matrix crystal size, matrix energy ...
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Recent advances in biomedical applications of accelerator mass spectrometry
... This technique is, however, very much in its infancy and it is not known, for the majority of drugs, whether the phar- macokinetics will be sufficiently linear so that the phar- macokinetics observed at the ...
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Assessment Of Fourteen Elemental Impurities In Doxapram Hydrochloride Drug Using Inductively Coupled Plasma Mass Spectrometry
... Abstract: The existence of elemental impurities in samples of pharmaceutical substances is a concern, not just due to significant toxic ity, and also due to the possible impact on drug stability, shelf - life, or ...
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Comparison of Two Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry Methods with Conventional Phenotypic Identification for Routine Identification of Bacteria to the Species Level
... temperature. Mass spectra were acquired using the MALDI-TOF spectrometer in a linear positive mode (Mi- croflex; Bruker ...Measured mass spectra ranged from 2,000 to 20,000 ...generated mass spectra ...
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Comparison of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and Molecular Biology Techniques for Identification of Culicoides (Diptera: Ceratopogonidae) Biting Midges in Senegal
... In conclusion, we report for the first time the successful iden- tification of epidemiologically important arthropods (Culicoides spp.) using mass spectrometry that was performed entirely in Af- rica. The ...
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Prospective Evaluation of a Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry System in a Hospital Clinical Microbiology Laboratory for Identification of Bacteria and Yeasts: a Bench by Bench Study for Assessing the Impact on Time to Identification and Cost Effectiveness
... atrix-assisted laser desorption ionization–time of flight mass spectroscopy (MALDI-TOF MS) is increasingly uti- lized by clinical microbiology laboratories for the identification of bacteria and yeasts (7, ...
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Utility of Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry following Introduction for Routine Laboratory Bacterial Identification
... Matrix-assisted laser desorption–ionization time of flight mass spectrometry (MALDI-TOF MS) has been shown to be both accurate in the identification of bacteria (1, 8, 9) and rapid (5, 10, 11, 13, ...
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