Linkage analyses
Contrasting identity by descent estimators, association studies, and linkage analyses using the Framingham Heart Study data
... Genetic linkage can be detected with pedigree data using inheritance vector ...two linkage analysis methods: 1) standard variance-components (VC) analy- sis using SOLAR, and 2) a novel conditional ...
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Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors
... We used the Rutgers map [7] for linkage analysis. We con- verted Kosambi map positions to Haldane map positions for analysis, although for ease of comparison with other GAW contributions we present all results on ...
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Effects on linkage analyses of different Affymetrix expression measures as quantitative trait phenotypes
... for linkage analyses was derived from the P1 physical map using the single-nucleotide polymor- phism (SNP) Mapping web application at the University College of Dublin (UCD) Conway Institute of Biomolecu- ...
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Genome-wide linkage analyses of two repetitive behavior phenotypes in Utah pedigrees with autism spectrum disorders
... for linkage analysis or as the dependent variable in association tests for specific ...ASD linkage signals in pedigrees with more abnormal levels of phrased speech delay [7,8], repetitive behavior [9-11] ...
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Has EU Accession Caused Structural Change in New Entrants? Intersectoral Linkage Analyses on Bulgaria and Romania
... intersectoral linkage analyses covering all economic activities aggregated to 34 sectors for the years of 1995, 2002, 2007 and ...forward linkage coefficients calculated from inverse matrices based ...
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Genome wide single nucleotide polymorphism linkage analyses of quantitative rheumatoid arthritis phenotypes in Caucasian NARAC families
... all linkage analyses (MINX, Merlin in X, for X chromo- some ...affect linkage signals [5]. Prior to analyses, unlikely genotypes were filtered by MERLIN, as described in online MERLIN ...
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Two dimensional linkage analyses of rheumatoid arthritis
... for linkage to three different RA-related traits one at a time: RA affection status and the quantitative phenotypes rheumatoid factor IgM and anti-cyclic citrullinated peptide ...These linkage ...
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Comparison of genome wide single nucleotide polymorphism linkage analyses in Caucasian and Hispanic NARAC families
... lower percentage of people carrying shared epitopes in Hispanics are interesting because the associations in that group with the shared epitopes are quite weak and tend to yield lower associations in general [8]. There ...
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Biased Estimation of the Recombination Fraction Using Half-Sib Families and Informative Offspring
... two-point linkage analyses and six families of Norwegian cattle was carried out to evaluate the implications of discarding noninformative offspring in practical ...
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Genome wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome wide linkage results
... genome-wide linkage scan results into the analysis of genome-wide association data by assigning single-nucleotide polymorphism (SNP) specific ...and linkage analysis results. For the NARAC study, we used ...
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Rat gene mapping using PCR-analyzed microsatellites.
... Table 1 lists 134 PCR-formatted markers corresponding to 1 18 loci, which were used for chromosomal assignment using somatic cell hybrid clones and/or linkage analyses..[r] ...
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Linkage and association analyses of principal components in expression data
... separate linkage analyses for each expression phenotype and found evidence of pleiotropy; multiple phenotypes showed link- age to the same region on chromosome ...perform analyses of composite ...
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Software for quantitative trait analysis
... Similar analyses could be carried out with any regression program, of course, but the packages listed above have the advantage of dealing with non-independence among family ...genotype analyses in unrelated ...
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Joint linkage and imprinting analyses of GAW15 rheumatoid arthritis and gene expression data
... detect linkage if the locus of interest is in fact ...in linkage analyses of quantitative traits. In our analyses of North American Rheumatoid Arthritis Consortium (NARAC) data, we used ...
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Functional variants of POC5 identified in patients with idiopathic scoliosis
... Idiopathic scoliosis (IS) is a spine deformity that affects approximately 3% of the population. The underlying causes of IS are not well understood, although there is clear evidence that there is a genetic component to ...
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A large sample of finnish diabetic sib pairs reveals no evidence for a non insulin dependent diabetes mellitus susceptibility locus at 2qter
... multipoint linkage analyses provide no consistent evidence for a major locus for NIDDM in our Finn- ish families near 2qter based on the best telomeric marker or- der above ...exclude linkage (multi- ...
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Genome-wide linkage using the Social Responsiveness Scale in Utah autism pedigrees
... multilocus linkage analysis on large extended pedigrees ...multipoint analyses, genetic information increases with the density of the gen- otypes [41-43] but is not decreased, with exclusion of markers in ...
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Integrating the markers Pan I and haemoglobin with the genetic linkage map of Atlantic cod (Gadus morhua)
... genetic linkage map data (this paper and Hubert et ...genetic linkage map data produced by a different group ...different linkage groups (Additional file ...the linkage map produced in the ...
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A genetic linkage map of sole (Solea solea): a tool for evolutionary and comparative analyses of exploited (flat) fishes
... a linkage map to better understand how evolution has shaped its genome ...a linkage map of sole based on 423 single nucleotide polymorphisms derived from expressed sequence tags and 8 neutral microsatellite ...
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NEW LOCI IN DICTYOSTELIUM DISCOIDEUM DETERMINING PIGMENT FORMATION AND GROWTH ON BACILLUS SUBTILIS
... Linkage analysis in Dictyostelium discoideum using multiply marked tester strains: establishment of linkage group VI1 and the reassessment of earlier linkage data.. whi[r] ...
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